The Study of Physical Parameters of Pb Modified Germanate Chalcogenide Glass

In the present paper we have studied the physical properties of Se-Sn-Pb chalcogenide material. The necessary physical parameters which have important role in determining the structure and strength of the material viz. constraints, coordination number, glass transition temperature etc. has been calculated. The decreasing trend has been found in cohesive energy, heat of atomization and mean bond energy. The glass transition has been studied using the Tichy-Ticha approach which also decreases. The decrease in these physical parameters is due to the increase of ionic character in the material. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/3559

Prediction and management of natural disasters through indigenous Technical Knowledge, with special reference to fisheries

Traditional Indigenous knowledge has over the years played a significant role in solving several major social-ecological problems including those related to climate change and variability. People living close to nature often observe the circumstances around them and are the often the first to identify and adapt to any changes. The appearance of certain birds, mating of certain animals and flowering of certain plants are all seen as important signals of change with respect to timing and seasonality of natural phenomena that are well understood in traditional knowledge systems. Indigenous and local peoples have relied on biodiversity as a buffer against environmental variation, change and catastrophe

Role of fiber morphology in thermal bonding

The aim of this research was to investigate the thermal point bonding process. Primary objectives were to carefully understand the changes taking place in the fiber structure due to applied heat and pressure, and the role of fiber morphology in determining optimum process conditions and the properties of the webs. To study fibers with varying morphology, i.e., from partially drawn as in spunbonding to fully drawn as in staple fiber nonwovens, fibers with a wide range of crystallinity and orientation were spun and characterized from a polypropylene resin. Thermally bonded carded webs were produced using these fibers and characterized in order to understand thermal bonding behavior of fibers with different morphology. The fibers with different morphologies differed in their bonding behavior. The fibers with higher molecular orientation and crystallinity tended to form a weak and brittle bond due to lack of polymer flow and fibrillation of the fibers in the bonded regions. In general, fibers with lower molecular orientation and lower crystallinity yielded stronger and tougher webs. Fibers with relatively less developed morphology also exhibited lower optimum bonding temperature. Significant morphological changes in fibers were observed during the thermal bonding process, in bonded as well as unbonded regions of the web. As a final step to see how the observations from staple fiber study translate to one of the relevant process during scale-up, spunbond studies were also conducted

Organic farming: Present status, scope and prospects in northern India

Organic agriculture has emerged as an important priority area globally in view of the growing consciousness for safe and healthy food, long term sustainability and environmental concerns despite being contentious in history. Green revolution although paved way for developing countries in self-sufficiency of food but sustaining production against the limited natural resource base demands has shifted steadily from “resource degrading” chemical agriculture to “resource protective” organic agriculture. The essential concept remains the same, i.e., to go back to the arms of nature and take up organic farming to restore the loss. Organic farming emphasizes on rotating crops, managing pests, diversifying crops and livestock and improving the soil. The rainfed areas particularly north-eastern regions where least or no utilization of chemical inputs due to poor resources provides considerable opportunity for promotion of organic farming thereby reflecting its vast but unexplored scope. However, significant barriers like yield reduction, soil fertility enhancement, integration of livestock, marketing and policy etc., arise at both macroscopic and microscopic levels; making practically impossible the complete adoption of ‘pure organic farming’; rather some specific area can be diverted to organic farming and thus a blend of organic and other innovative farming systems is needed. Adoption of Integrated Green Revolution Farming can be possible to a large extent, where the basic trends of green revolution are retained with greater efficiency and closer compatibility to the environment. This review paper attempts to present the recent global and regional scenario of organic farming particularly highlighting the scope, prospects and constraints in the northern areas

A RETROSPECTIVE EVALUATION OF TREATMENT STRATEGIES FOR UNSTABLE INTERTROCHANTERIC FEMORAL FRACTURES IN THE ELDERLY: COMPARING PROXIMAL FEMORAL NAIL ANTI-ROTATION VERSUS PRIMARY HIP HEMIARTHROPLASTY.

Objectives The present investigation aims to contrast the outcomes of proximal femoral nail anti-rotation (PFNA) and primary hemiarthroplasty for treating unstable intertrochanteric femoral fractures in geriatric patients, focusing on functional outcomes, complication rates, and postoperative rehabilitation protocols. Methods The retrospective study, conducted at Pt. JLN Govt. Medical College, Chamba, Himachal Pradesh, contrasted the outcomes of proximal femoral nail anti-rotation (PFNA) and cemented hemiarthroplasty for unstable intertrochanteric femoral fractures (IFFs). Patients with American Society of Anesthesiologists (ASA) Grades II and III, aged over 65 years, in addition to having AO types A2 and A3 fractures were included in this study. Surgical procedures involved PFNA device insertion or hemiarthroplasty, followed by standardized post-operative protocols. Results The comparative analysis between the PFNA group (n = 50) and the Primary Hemiarthroplasty of the Hip (PHH) group (n = 43) revealed significant differences in treatment outcomes. Notably, the PFNA group exhibited a higher Harris Hip score at the 12-month follow-up (90.26 vs. 82.4, p = 0.016), with a larger proportion achieving excellent outcomes (36 vs. 23). Moreover, secondary outcomes, including surgical time, intra-operative blood loss, post-operative hemoglobin levels, and duration of hospital stay, favored the PFNA group, showing statistically significant differences (p < 0.00001, except for perioperative blood transfusions, p = 0.00536). Conclusion The findings of the investigation implied that PFNA fixation gives rise to superior clinical outcomes when compared to PHH for unstable intertrochanteric femoral fractures. This has been proven by the identification of better functional scores and reduced post-operative complications in the case of patients treated with PFNA. Recommendation The study recommends prioritizing PFNA fixation over primary hemiarthroplasty for unstable intertrochanteric femoral fractures based on superior functional outcomes and fewer post-operative complications

EFFECTS OF MINIMALLY INVASIVE PLATE OSTEOSYNTHESIS (MIPO) ON PATIENTS WITH DISTAL TIBIA FRACTURES: A CROSS-SECTIONAL STUDY.

Background Distal tibia fracture accounts for around 6-11% of tibia fractures. A distal tibia fracture is also known as a Pilon fracture. A distal tibia fracture is not easy to handle. The prime motive of this research is to examine the result of minimally invasive plate osteosynthesis for distal tibia fractures. Materials and Methods A cross-sectional study was conducted, and 107 patients were included in this research. All the detailed history of the patients was recorded. Complete lesion detersion was first done. Advance soft tissue covering is performed if needed. Plates are arranged on the lateral side of the tibia. If it is required, extra cortical screw utilizing minimally invasive plate osteosynthesis. Results The study examined the effects of Minimally Invasive Plate Osteosynthesis (MIPO) on distal tibia fracture patients found 70 males, 37 females, with most aged 30-40 years (45), then 40-50 years (40), 20-30 years (13), and 50-60 years (9). Professions varied: farmers (50), businessmen (35), daily wage workers (11), office workers (11). Road accidents caused 65 injuries, falls 42. Injuries were split between right (52) and left sides (55). These insights deepen understanding of MIPO's impact on distal tibia fracture patients. Conclusion The study indicates that minimally invasive plate osteosynthesis (MIPO) has minimal impact on blood circulation, promoting faster recovery with less hematoma and trauma. MIPO also accelerates bone union, requiring minimal time and no specialized instruments. Non-union reasons include pressure, fragment issues, and fracture design. Recommendation Minimally invasive plate osteosynthesis is a safe, effective treatment for distal tibia fractures, yielding quick bone union, improved leg mobility, and ample blood supply to the periosteum. It's a favorable option for treating such fractures

CFD Simulation Studies on Integrated Approach of Solar Chimney and Borehole Heat Exchanger for Building Space Conditioning

In this communication, integrated approach of solar chimney and borehole heat exchanger has been studied by using computational fluid dynamics software. It is observed that, the room temperature can be maintained at 25-30 °C, at 4.9 ACH with this integrated approach in both peak summer and winter conditions. The cooling and heating effects are evaluated as 4.73-5.55 kW at 40 °C in summer and 8.27-10.56 kW at 5 °C in winter. The SC-BHE integrated system approach produced 21-37 % higher heating effect than the BHE alone system. In cooling mode SC fitted after the room in fluid circuit and it produces the induce effect for air suction from BHE along the air blower. So, integrated approach is a feasible solution for building space conditioning

Genetically Modified Myoglobin As A Mimic For Heme Enzymes

This study addresses the mechanistic relationships between formation of reactive oxygen species (ROS) and their catalytic oxidation functions in oxygenation and peroxygenation reactions in heme enzymes. Even though both cytochrome P450s (CYP P450s) and peroxidases have different catalytic activities, the involvement of common ROS (Compound 0 and Compound I) have been proposed. Therefore, to understand the generation and activation of peroxide to form ROS, genetically-engineered myoglobin (Mb) mutants were created by incorporating redox-sensitive 3-amino-L-tyrosine (NH2Tyr) or L-3, 4-dihydroxyphenylalanine (DOPA) into its active site. Distal His 64 replaced with redox amino acids mutant Mb showed excellent turnover rates for thioanisole and benzaldehyde oxidation, compared to the wild-type protein. A 9-fold and 81-fold increase in activity, respectively, was observed in the presence of hydrogen peroxide (H2O2). The presence of a redox unnatural amino acid in the active site enhances the rate of compound I (Cpd I) formation and stabilizes it to form one extra H-bond as compared to the wild type (WT) Mb. This increased oxidation activity in mutants offer insights into the role of the distal active site residues which are involved in acid-base catalysis and distal charge relay pull effect in peroxide activation and formation of ROS in heme proteins.Furthermore, cyclic voltammetry (CV) and atomic force microscopy (AFM) were used to investigate the importance of active site orientation of an immobilized protein for direct electron transfer (DET) and electrocatalysis. While the bioconjugated wild-type myoglobin (WT Mb) was immobilized on the modified gold electrode surface in a random multilayered fashion, the Ser 3 replaced with NH2Tyr in Mb mutant, was immobilized via a Diels-Alder reaction specific to the NH2Tyr residue to form a homogeneous monolayer. Electrochemical calculations for the number of surface exposed redox-sensitive molecules on the electrode surface (Γ) and heterogeneous rate constant for DET were 1.29 × 10-10 mol cm-2; 2.3 sec-1 for the WT Mb and 1.54 × 10-10 mol cm-2; 1.3 sec-1 for the S3NH2Tyr Mb mutant, respectively. Electro-catalytic conversion of thioanisole to sulfoxide products showed similar turnover frequencies (TOF) around 1.9 × 103 sec-1 (with 87% conversion) for the WT Mb, and 1.5 × 103 sec-1 for the mutant Ser 3-amino-L-tyrosine (S3NH2Tyr) Mb (with 81% conversion). These results indicate that site-directed single monolayer immobilization affords almost the same number of surface exposed Mb active sites as the random multilayer immobilization strategy, though the latter contains a greater number of protein molecules on the electrode surface. The microarray concept development provides novelty to study protein-protein interactions, drug discovery, and biomedical and proteomic research

The Role of Quantum Computing in Cloud Security

Quantum computing represents a paradigm shift in computational capabilities, promising to solve complex problems beyond the reach of classical computers. This advancement has significant implications for cloud security, a cornerstone of modern digital infrastructure. Quantum computing poses both opportunities and threats to cloud security mechanisms, particularly in the realms of cryptography, data encryption, and threat detection. This research explores the dual impact of quantum computing on cloud security, examining how quantum algorithms can enhance security protocols and simultaneously undermine existing cryptographic standards. Through a comprehensive literature review, case studies, and empirical data analysis, the study identifies key areas where quantum computing intersects with cloud security, including quantum-resistant cryptographic methods, quantum key distribution (QKD), and the potential for quantum-enhanced security analytics. The findings indicate that while quantum computing can bolster cloud security through advanced encryption techniques and enhanced data integrity, it also necessitates the urgent development and adoption of post-quantum cryptography to safeguard against quantum-enabled cyber threats. The research concludes with strategic recommendations for integrating quantum technologies into cloud security frameworks, emphasizing the need for proactive measures to mitigate risks and leverage quantum advantages effectively. This study contributes to the understanding of quantum computing’s role in shaping the future landscape of cloud security, offering valuable insights for practitioners, policymakers, and researcher