Well-being at Work and Employee Performance: Towards Managerial Practice Reframing in the Digitalization Process - Moroccan Context

Abstract With an increasingly competitive and dynamic economic environment, employees' well-being at work is increasingly regarded as a strategic catalyst for Human Resources Managers (HRMs) to enhance employees' commitment and company performance. The current research discusses the interplay between employee well-being and performance with the goal of establishing a managerial model tailored to the specific needs of companies in Morocco. Despite a multitude of theoretical frameworks of motivation and job satisfaction as described in contemporary literature, few studies adopt a contextual and qualitative approach to analyze this connection in emerging economies where organizational processes and cultural traditions affect the association. Based on qualitative research using semi-structured interviews of HRMs in Moroccan SMEs, the study elicits some common themes. They are the concept of well-being as a source of performance, motivational drivers like autonomy and appreciation, and monitoring devices of well-being (e.g., social barometers, informal feedback). The study suggests that where well-being is embedded in company culture, there is a more engaged, productive, and resilient workforce. The proposed managerial model incites concrete and context-related actions: creating a healthy work climate, promoting autonomy and appreciation, ensuring flexibility, and implementing repeated well-being reviews. This is an attempt to reconcile the workers' expectations with the organizational necessities of performance and competitiveness. The integration of well-being into strategic management enables SMEs not only to improve worker satisfaction but also to ensure long-term organizational resilience.   Keywords: Workplace well-being, Organizational Performance, Moroccan SMEs, Human Resource Management, Employee Motivation, DigitalizationAbstract With an increasingly competitive and dynamic economic environment, employees' well-being at work is increasingly regarded as a strategic catalyst for Human Resources Managers (HRMs) to enhance employees' commitment and company performance. The current research discusses the interplay between employee well-being and performance with the goal of establishing a managerial model tailored to the specific needs of companies in Morocco. Despite a multitude of theoretical frameworks of motivation and job satisfaction as described in contemporary literature, few studies adopt a contextual and qualitative approach to analyze this connection in emerging economies where organizational processes and cultural traditions affect the association. Based on qualitative research using semi-structured interviews of HRMs in Moroccan SMEs, the study elicits some common themes. They are the concept of well-being as a source of performance, motivational drivers like autonomy and appreciation, and monitoring devices of well-being (e.g., social barometers, informal feedback). The study suggests that where well-being is embedded in company culture, there is a more engaged, productive, and resilient workforce. The proposed managerial model incites concrete and context-related actions: creating a healthy work climate, promoting autonomy and appreciation, ensuring flexibility, and implementing repeated well-being reviews. This is an attempt to reconcile the workers' expectations with the organizational necessities of performance and competitiveness. The integration of well-being into strategic management enables SMEs not only to improve worker satisfaction but also to ensure long-term organizational resilience.   Keywords: Workplace well-being, Organizational Performance, Moroccan SMEs, Human Resource Management, Employee Motivation, Digitalizatio

WELL-BEING AT WORK: PERCEPTION OF HUMAN RESOURCES MANAGERS- AN EXPLORATORY CONTEXTUALIZATION STUDY

In a context where labor market competitiveness is intense and the quest for productivity is relentless, well-being at work emerges as a crucial pillar and strategic challenge for Human Resources Managers concerning employee performance and retention. HR professionals are increasingly viewed as strategic partners in driving organizational success. This study contributes to the field by deepening the research on HRMs' perceptions of workplace well-being from an employer's perspective. By focusing specifically on how HR professionals perceive and address well-being at work, this research offers valuable insights into their strategic role and the challenges they face. This perspective is crucial for understanding the employer's viewpoint on well-being and for developing targeted strategies that align with organizational goals in Morocco. This study explores the concept of well-being at work from the perspective of HRMs in Morocco through a qualitative study based on semi-structured interviews with HR professionals across various sectors. The theoretical foundation is rooted in Karasek and Theorell's Demand-Control-Support model, Ryff's Psychological Well-Being model, and Seligman's PERMA model. We have chosen an integrative research model that combines these theoretical perspectives to offer a more comprehensive understanding of complex phenomena. The study contributes theoretically by applying these models to the Moroccan context, revealing unique challenges and perceptions that enrich the global discourse on workplace well-being. The study emphasizes that focusing on well-being is crucial for enhancing organizational performance, strengthening employer branding, and reducing turnover. Adopting a strategic approach to well-being can significantly improve organizational outcomes and foster a more engaged workforce. By integrating theoretical models with empirical data, this study provides a robust framework for understanding and enhancing well-being at work, thereby contributing to both academic literature and practical management strategies within the Moroccan context

WELL-BEING AT WORK: PERCEPTION OF HUMAN RESOURCES MANAGERS- AN EXPLORATORY CONTEXTUALIZATION STUDY

In a context where labor market competitiveness is intense and the quest for productivity is relentless, well-being at work emerges as a crucial pillar and strategic challenge for Human Resources Managers concerning employee performance and retention. HR professionals are increasingly viewed as strategic partners in driving organizational success. This study contributes to the field by deepening the research on HRMs' perceptions of workplace well-being from an employer's perspective. By focusing specifically on how HR professionals perceive and address well-being at work, this research offers valuable insights into their strategic role and the challenges they face. This perspective is crucial for understanding the employer's viewpoint on well-being and for developing targeted strategies that align with organizational goals in Morocco. This study explores the concept of well-being at work from the perspective of HRMs in Morocco through a qualitative study based on semi-structured interviews with HR professionals across various sectors. The theoretical foundation is rooted in Karasek and Theorell's Demand-Control-Support model, Ryff's Psychological Well-Being model, and Seligman's PERMA model. We have chosen an integrative research model that combines these theoretical perspectives to offer a more comprehensive understanding of complex phenomena. The study contributes theoretically by applying these models to the Moroccan context, revealing unique challenges and perceptions that enrich the global discourse on workplace well-being. The study emphasizes that focusing on well-being is crucial for enhancing organizational performance, strengthening employer branding, and reducing turnover. Adopting a strategic approach to well-being can significantly improve organizational outcomes and foster a more engaged workforce. By integrating theoretical models with empirical data, this study provides a robust framework for understanding and enhancing well-being at work, thereby contributing to both academic literature and practical management strategies within the Moroccan context

A prospective clinical trial to evaluate the role of very low dose mifepristone 10 mg in medical management of uterine leiomyoma in tertiary care hospital from North West India

Background: Uterine leiomyomas are the most common benign tumours of the uterus and also the most common benign solid tumor in female. It arises from the uterine smooth muscles (myometrium) but contain varying amount of fibrous connective tissue. Aim of study was to evaluate the efficacy of very low dose Mifepristone (10 mg) on leiomyoma volume and its related symptoms.Methods: This was a prospective clinical study. 30 women met with the inclusion criteria and giving informed consent for the study.Results: Mean myoma volume was 60.32±51.89 at initial visit and 36.13±48.54 at 3 months follow up visit with 40.1% reduction which was statistically significant difference (p < 0.001). Mean PBAC score in Group I was 155.53±21.70 at initial visit and 0.97±2.97 at 3 months follow up visit with 99.3% reduction which was statistically significant (p < 0.001).Conclusions: Mifepristone 10 mg is efficacious in term of control of bleeding, alleviation of pain related symptoms with few side effects. So low dose mifepristone can be used as a suitable option for women with symptomatic fibroids in perimenopausal periods or patients not willing or fit for surgery

Enhancing of a wind power system control using intelligent artificial control and multilayer inverter

The improvement of overall power quality and optimal control of reactive and active power are issues that have attracted many researchers. The harmonic is considered a main stressful source for energy quality. This paper proposed the ability of artificial intelligence at controlling the active and reactive power and to reduce torque ripple and current harmonics thus improve energy quality and the stability of system, that by using the artificial intelligence controller and a neural network based space vector modulation with two levels inverter (NSVM-2L). These inverter hold the offer improved efficiency and have on account of their capability of high voltage operation compared with traditional inverters as reducing the harmonic. These results showed that the fuzzy logic controller's dynamic performance is very superior to that of the PID controller of DFIG. The fuzzy controller works well for helping us to minimize the rate of harmonic distortion of absorbed currents and for correctly adjusting active and reactive power and its stability of wind turbine compared to PID controller

Gene array of PDL cells exposed to Osteogain in combination with a bone grafting material.

OBJECTIVES The aim of the present study was to investigate the effects of Osteogain, a new formulation of enamel matrix derivative (EMD) in combination with a grafting material on a wide variety of genes for cytokines, transcription factors and extracellular matrix proteins involved in osteoblast differentiation. MATERIALS AND METHODS Primary human periodontal ligament (PDL) cells were seeded on natural bone mineral (NBM) particles coated with Osteogain for 24 h and analyzed for regulated gene expression using a human osteogenesis gene super-array kit. Osteoblast-related genes include those transcribed during bone mineralization, ossification, bone metabolism, cell growth and differentiation as well as gene products representing extracellular matrix molecules, transcription factors and cell adhesion molecules. RESULTS Osteogain significantly upregulated the expression of over 20 of the 100 genes examined including bone morphogenetic protein 2 (BMP2), TGFβ1, fibroblast growth factor (FGF), epidermal growth factor (EGF) and platelet-derived growth factor (PDGF) as well as some of their associated receptors. Osteogain also promoted gene expression of a number of osteoblast differentiation markers including collagen1α2 and alkaline phosphatase as well as cell adhesion molecules including fibronectin and a variety of integrin binding proteins. Interestingly, Osteogain promoted calcitonin receptor 55-fold and also promoted annexin A5 gene expression over 12-fold. CONCLUSION The present study demonstrates that Osteogain is capable of either upregulating or downregulating the expression of a wide variety of genes including those for growth factors and cytokines when combined with a bone grafting material. CLINICAL RELEVANCE The results from the present study demonstrate the large and potent effect of addition of Osteogain in combination to a bone grafting material over a wide variety of genes supporting osteogenesis

Bone grafting material in combination with Osteogain for bone repair: a rat histomorphometric study.

OBJECTIVES Enamel matrix derivative (EMD) has been successfully used for the regeneration of periodontal tissues including new cementum, periodontal ligament, and alveolar bone. Combination of EMD with bone grafting materials has however generated variable clinical results. Recently, we have demonstrated that a new formulation of EMD in a liquid carrier system (Osteogain®) has improved physicochemical properties for the adsorption of EMD to a bone grafting material. The aim of the present study was to investigate the regenerative potential of Osteogain®, in combination with a bone graft, on new bone formation in a rat femur defect model. MATERIALS AND METHODS Fifty-four critically sized femur defects (3 mm in diameter) were created bilaterally in 27 rats and treated following the group allocation: (1) drilled unfilled control, (2) a natural bone mineral (NBM), and (3) NBM + Osteogain®. All defects were histologically analyzed at 2, 4, and 8 weeks after surgical intervention. Micro-CT analysis, hematoxylin and eosin (H&E) staining, and Safranin O staining were performed to quantify new bone formation. RESULTS Significantly more new bone formation was observed in defects treated with NBM + Osteogain® at both 4 and 8 weeks when compared to NBM alone and the control unfilled defects (P < 0.05). Histologically, the formation of more mature mineralized bone with the presence of osteocytes were found more commonly in defects treated with Osteogain® + NBM at 8 weeks post-healing when compared to NBM alone. CONCLUSIONS The present study demonstrate that Osteogain® in combination with a bone grafting material improves the speed and quality of new bone formation in rat osseous defects. CLINICAL RELEVANCE Future clinical research are now warranted to fully characterize the benefits of Osteogain®, a new formulation of enamel matrix proteins delivered in liquid formation when used in combination with a bone grafting material

Antigenic, structural, and functional relationships between fimbriae and the hemagglutinating adhesin HA-Ag2 of Porphyromonas gingivalis

While the adhesive properties of Porphyromonas gingivalis are known to allow colonization of the subgingival tissues, the roles of fimbriae and adhesin molecules in hemagglutination remain unclear. The purpose of this study was to analyze the antigenic, structural, and functional relationships of these two components. Five populations of monoclonal antibodies were produced against (i) the hemagglutinating adhesin HA-Ag2 resolved by crossed immunoelectrophoresis (CIE), (ii) native fimbriae, and (iii) each of the three immunoprecipitates, Ag8a, Ag8b, and Ag8c, that define fimbriae by CIE. The tests used for characterization of the monoclonal antibodies included immunoblot reactivity, inhibition of hemagglutination, capacity to dissociate immunoprecipitates by CIE, localization of recognized epitopes by immunoelectron microscopy, and epitope mapping by competition enzyme-linked immunosorbent assay. The results from the different immunochemical tests clearly showed a close antigenic relationship between fimbriae and the hemagglutinating adhesin HA-Ag2. We were able to establish that the epitopic domain H1 of HA-Ag2 is hemagglutinin specific and that domain F2 is fimbria specific. Our data indicate that the polymeric structural unit of fimbriae must be complexed to HA-Ag2, the adhesin, to confer hemagglutination activity to the bacterial cells.</jats:p

Molecular size variation of the hemagglutinating adhesin HA-Ag2, a common antigen of <i>Bacteroides gingivalis</i>

The array of Bacteroides gingivalis W83 antigens revealed by crossed Immunoelectrophoresis includes one antigen that is associated with an erythrocyte-binding capacity, termed the hemagglutinating adhesin HA-Ag2. This antigen was excised from crossed-immunoelectrophoresis plates to produce two polyclonal antisera, VL 011 and WL 303, whose restricted specificity for HA-Ag2 was assessed using crossed Immunoelectrophoresis, crossed Immunoelectrophoresis with an intermediate gel, and crossed imunoaffinoelectrophoresis. Both antisera, when used to probe blots of an EDTA cell surface extract of B. gingivalis W83, reacted with two bands, at 33 and 38 kDa, which were also detected by a monoclonal antibody (Naito et al. 1985. Infect. Immun. 50:231–235), specific for a hemagglutinin of B. gingivalis. Antiserum WL 303 was used to examine by immunoblotting the distribution of HA-Ag2 among a variety of human and animal strains of B. gingivalis. All human strains tested showed two major bands at 33 and 38 kDa in the EDTA cell surface extract, and at 43 and 49 kDa in outer membrane preparations. Only one band, at 29 kDa, was detected in EDTA cell surface extracts from the animal strains, while the outer membrane preparation of a single strain showed a positive reaction. We concluded that HA-Ag2 is an antigen common to human and animal strains of B. gingivalis and that its subunits may show heterogeneity in apparent molecular mass. Key words: Bacteroides, EDTA extract, outer membranes, crossed immunoelectrophoresis, immunoblot. </jats:p

human whole blood model

Periodontitis is characterized by an accumulation of inflammatory cells in periodontal tissue and subgingival sites. Leukocytes play a major role in the host response to Porphyromonas gingivalis, a major aetiological agent of chronic periodontitis. Secretion of high levels of inflammatory mediators, including cytokines and prostaglandins, by leucocytes is believed to contribute to periodontal tissue destruction. The aim of this study was to investigate the inflammatory response of an ex vivo whole blood model to P. gingivalis stimulation. The production of interleukin-1 beta (IL-1β), IL-4, IL-5, IL-6, IL-8, IL-10, IL-12p70, IL-13, tumour necrosis factor alpha (TNF-α), interferon gamma (IFN-γ), IFN-γ-inducible protein 10 (IP-10), monocyte chemoattractant protein-1 (MCP-1), Regulated on Activation Normal T cell Expressed and Secreted (RANTES) and prostaglandin E(2) (PGE(2)) were quantified by enzyme-linked immunosorbent assays. P. gingivalis induced the secretion of the pro-inflammatory cytokines IL-1β, TNF-α, IL-6 and IFN-γ, the chemokines IL-8, RANTES and MCP-1 and the inflammatory mediator PGE(2) in an ex vivo human whole blood model. The secretion levels were dependent on the strain and the infectious dose used. While the mediator profiles were comparable between six healthy subjects, a high interindividual variability in the levels of secreted mediators was observed. This study supports the view that P. gingivalis, by inducing high levels of inflammatory mediators from a mixed leucocyte population, can contribute to the progression of periodontitis