Rekrutmen Bakal Calon Walikota dan Wakil Walikota Koalisi Partai Demokrat, Gerindra, dan Pks pada Pilkada Kota Pekanbaru Tahun 2017

The research is based on regional election in Pekanbaru City 2017 to choosed Mayor and Vice Mayor. Regional election was held on 15 February 2017. Candidates for Mayor and Vice Mayor is Syahril-Said Zohrin, Herman Nazar-Defiwwarman, Firdaus-Ayat Cahyadi and Dastrayani Bibra-Said Usman. The Mayor and Vice Mayor is elected incumbent candidates Firdaus and Ayat Cahyadi from coalition Demokrat party, Gerindra and PKS.The purpose of this result is to know recruitment mechanism from Demokrat Party, Gerindra and PKS to choose the candidates and to know factor the coalition. Method used in this research is descriptive methods with qualitative type. Types of data on this researchis primary and secondary data. The data collected in this research is documentation and interview. The technical data analysis used is descriptive qualitative data analysisThe result is Demokrat Party, Gerindra and PKS have their own recruitment mechanism. Democrat Party and Gerindra would selected and test the candidates and PKS would voted the candidates in publicly internal. Those who are selected candidates of Demokrat Party, Gerindra and PKS are chosen by the board of the leadership center party in Jakarta. Factor of the coalition is the same vision and mission, the figur of the candidates, sustainability of the progamme and other

Performance of CareStart™ Malaria Pf/Pv Combo test for the diagnosis of Plasmodium falciparum and Plasmodium vivax infections in the Afar Region, North East Ethiopia

Background: CareStart™ Malaria Pf/Pv Combo test has shown encouraging results for the diagnosis of P. falciparum and P. vivax infections in Ethiopia. Nevertheless, the performance of the test could be affected by different factors like gene polymorphisms, excess heat and humidity. Hence, evaluation of the performance of the test in different settings in Ethiopia is vital for the routine diagnosis of malaria.Objective: To evaluate the diagnostic performance of CareStartTM Malaria Pf/Pv Combo test for the diagnosis of P. falciparum and P. vivax infections in the Afar Region, Northeast Ethiopia.Methods: Finger prick blood samples were collected from a total of 1092 patients who had malaria symptoms and visited three different health facilities in the Afar Region. Giemsa-stained thin and thick blood smears were prepared and microscopically examined under 100 × magnifications for Plasmodium species identification and determination of parasitaemia. CareStart Malaria Pf/Pv Combo test was also performed as per the manufacturer's instructions. The sensitivity and the specificity of the test was determined using microscopy as gold standard.Results: The sensitivity and specificity of the test were 98.5% and 98.0% respectively, with a positive predictive value (PPV) of 91.7% and a negative predictive value (NPV) of 99.7% for the diagnosis of P. falciparum infection. The corresponding sensitivity and specificity for the diagnosis of P. vivax infection were 100% and 99.6% respectively, with PPV and NPV of 86.2% and 100%, respectively.Conclusion: The results of this study revealed high sensitivity and specificity of CareStartTM Malaria Pf/Pv Combo test for the diagnosis of both P. falciparum and P. vivax infections in the study area, though additional study may be needed in the most peripheral hottest areas of the region. [Ethiop. J. Health Dev. 2011;25(3):206-211

Burden of carpal tunnel syndrome and its associated factors among construction industry workers in Gondar town, Ethiopia

Background Carpal tunnel syndrome is characterized by symptoms such as pain, numbness, or tingling on the anterior surface of the index, middle, or radial half of the ring finger, which is frequently associated with weakness of hand grip, and nocturnal pain and/or numbness resulting from compression of the median nerve at the carpal tunnel between the carpal bones and the transverse ligament. The construction industry involves many activities aside from the building process, such as landscaping, painting, electrical supply, plastering, paving, and telecommunications. Performing such tasks involves repetition of wrist flexion and extension, forceful grip with the hand, and/or vibrations of the hand and arm. This study aimed to assess the prevalence of carpal tunnel syndrome and its associated risk factors among construction workers. Method An institutional-based cross-sectional study design was conducted among six construction sectors in Gondar from April to July 2021. An interviewer-administered questionnaire was prepared from the literature with a Katz hand diagram, and a physical examination and a special test (carpal compression test, Phalen s, and Tinel s test) were carried out for those participants who reported pain during the interview. Binary logistic regression was conducted with SPSS 25 to identify the associated risk factors for carpal tunnel syndrome. The strength of the association was detected by the adjusted odds ratio. Result A total of 333 study participants aged 18-70 years were included in this study. Among the participants, 11.7 (AOR 95 CI 8.1-15.3) had carpal tunnel syndrome. Age, cigarette smoking, work experience, and working with finger-pressing tools were risk factors significantly associated with carpal tunnel syndrome among construction workers with a i p /i -value of andlt 0.05. Conclusion The magnitude of carpal tunnel syndrome was 11.7 among construction workers. Being of older age, having more experience, cigarette smoking, and workin

Assessment of animal African trypanosomiasis (AAT) vulnerability in cattle-owning communities of sub-Saharan Africa

Background: Animal African trypanosomiasis (AAT) is one of the biggest constraints to livestock production and a threat to food security in sub-Saharan Africa. In order to optimise the allocation of resources for AAT control, decision makers need to target geographic areas where control programmes are most likely to be successful and sustainable and select control methods that will maximise the benefits obtained from resources invested. Methods: The overall approach to classifying cattle-owning communities in terms of AAT vulnerability was based on the selection of key variables collected through field surveys in five sub-Saharan Africa countries followed by a formal Multiple Correspondence Analysis (MCA) to identify factors explaining the variations between areas. To categorise the communities in terms of AAT vulnerability profiles, Hierarchical Cluster Analysis (HCA) was performed. Results: Three clusters of community vulnerability profiles were identified based on farmers’ beliefs with respect to trypanosomiasis control within the five countries studied. Cluster 1 communities, mainly identified in Cameroon, reported constant AAT burden, had large trypanosensitive (average herd size = 57) communal grazing cattle herds. Livestock (cattle and small ruminants) were reportedly the primary source of income in the majority of these cattle-owning households (87.0 %). Cluster 2 communities identified mainly in Burkina Faso and Zambia, with some Ethiopian communities had moderate herd sizes (average = 16) and some trypanotolerant breeds (31.7 %) practicing communal grazing. In these communities there were some concerns regarding the development of trypanocide resistance. Crops were the primary income source while communities in this cluster incurred some financial losses due to diminished draft power. The third cluster contained mainly Ugandan and Ethiopian communities which were mixed farmers with smaller herd sizes (average = 8). The costs spent diagnosing and treating AAT were moderate here. Conclusions: Understanding how cattle-owners are affected by AAT and their efforts to manage the disease is critical to the design of suitable locally-adapted control programmes. It is expected that the results could inform priority setting and the development of tailored recommendations for AAT control strategies

Mapping 123 million neonatal, infant and child deaths between 2000 and 2017

Since 2000, many countries have achieved considerable success in improving child survival, but localized progress remains unclear. To inform efforts towards United Nations Sustainable Development Goal 3.2—to end preventable child deaths by 2030—we need consistently estimated data at the subnational level regarding child mortality rates and trends. Here we quantified, for the period 2000–2017, the subnational variation in mortality rates and number of deaths of neonates, infants and children under 5 years of age within 99 low- and middle-income countries using a geostatistical survival model. We estimated that 32% of children under 5 in these countries lived in districts that had attained rates of 25 or fewer child deaths per 1,000 live births by 2017, and that 58% of child deaths between 2000 and 2017 in these countries could have been averted in the absence of geographical inequality. This study enables the identification of high-mortality clusters, patterns of progress and geographical inequalities to inform appropriate investments and implementations that will help to improve the health of all populations

Neonatal outcomes of preterm neonates and its predictors in Ethiopian public hospitals: Multicenter prospective follow-up study

Introduction Preterm birth remains the most significant clinical and public health encounter Preterm infant outcomes pose key evidence for clinicians and policymakers and are extensively used to set clinical and policy verdicts to improve services It is necessary to conduct the outcomes of neonates frequently as it varies from place to place and even from time to time in a similar place There is limited literature in Ethiopia about preterm neonates outcomes and their predictors Objective This study aimed to assess the neonatal outcomes of preterm neonates and their predictors in South Gondar zone public hospitals Northwest Ethiopia 2021 Methods A prospective observational study was employed on 462 preterm neonates in South Gondar Zone Public Hospitals The data were entered into Epidata 4 6 and analyzed using STATA version 16 MP software A parametric log normal survival model was used to identify possible predictors for preterm neonate death Statistical significance was declared at a i P i value less than 0 05 Result The overall preterm survival rate was 71 1 95 CI 66 7 75 1 Thirty six percent of preterm neonates were diagnosed with sepsis One fourth of the neonates had respiratory distress syndrome Gestational age greater than 34 weeks 1 04 95 CI 0 53 1 56 respiratory distress syndrome 0 85 95 CI 0 49 1 22 body mass index 1 34 95 CI 1 87 0 80 non union marital status 0 71 95 CI 1 34 0 09 multiple pregnancies 0 66 95 CI 0 99 0 32 multiparous 0 35 95 CI 0 01 0 69 hypothermia 1 19 95 CI 1 76 0 62 Kangaroo Mother Care 1 9 95 CI 2 34 1 41 and non cephalic presentation 1 23 95 CI 1 99 0 46 were significant predictors Conclusion In this study the preterm survival rate was low Gestational age greater than 34 weeks no respiratory distress syndrome and multiparous mothers were positively associated with the survival of preterm neonates Though high pre pregnancy maternal body mass index non union marital status of mothers multiple pregnancies hypothermia Kangaroo mother care

Asthma-associated genetic variants induce IL33 differential expression through an enhancer-blocking regulatory region

Genome-wide association studies (GWAS) have implicated the IL33 locus in asthma, but the underlying mechanisms remain unclear. Here, we identify a 5 kb region within the GWAS-defined segment that acts as an enhancer-blocking element in vivo and in vitro. Chromatin conformation capture showed that this 5 kb region loops to the IL33 promoter, potentially regulating its expression. We show that the asthma-associated single nucleotide polymorphism (SNP) rs1888909, located within the 5 kb region, is associated with IL33 gene expression in human airway epithelial cells and IL-33 protein expression in human plasma, potentially through differential binding of OCT-1 (POU2F1) to the asthma-risk allele. Our data demonstrate that asthma-associated variants at the IL33 locus mediate allele-specific regulatory activity and IL33 expression, providing a mechanism through which a regulatory SNP contributes to genetic risk of asthma.This work was supported by NIH grants R01 HL118758, R01 HL128075, R01 HL119577, R01 HL085197, U19 AI095230, UG3 OD023282 and UM1 AI114271

Personal and driving related characteristics as predictors of risky driving behavior among drivers in Debre Tabor Town, Northwest Ethiopia: A mixed method study

Objective: This study aimed to assess the risky driving behavior and associated factors among drivers in Debre Tabor town, Ethiopia, 2020. Methods: This study was a mixed type community-based cross-sectional survey of 564 and 11 participants for quantitative and qualitative study by using a self-administered questionnaire and an interview method, respectively, and the analysis was carried out in 2021. Results: Eighty-two-point one percent (82.1%) of drivers were engaged in risky driving behavior. Driving at night, never attending religious events/ceremonies, driving >8 h/day, believing income is insufficient, weak law enforcement, training institutions problem, being Bajaj driver, and being a non-governmental-driver were significantly associated with risky driving behavior. Conclusion: Risky driving behavior was high among drivers. Being non-governmental driver was the protective factor of risky driving behavior however the rest variables were the risk factors for risky driving behavior. To overcome the problem, appropriate law enforcement measures should be taken