Turbo-like Iterative Multi-user Receiver Design for 5G Non-orthogonal Multiple Access

Non-orthogonal multiple access (NoMA) as an efficient way of radio resource sharing has been identified as a promising technology in 5G to help improving system capacity, user connectivity, and service latency in 5G communications. This paper provides a brief overview of the progress of NoMA transceiver study in 3GPP, with special focus on the design of turbo-like iterative multi-user (MU) receivers. There are various types of MU receivers depending on the combinations of MU detectors and interference cancellation (IC) schemes. Link-level simulations show that expectation propagation algorithm (EPA) with hybrid parallel interference cancellation (PIC) is a promising MU receiver, which can achieve fast convergence and similar performance as message passing algorithm (MPA) with much lower complexity.Comment: Accepted by IEEE 88th Vehicular Technology Conference (IEEE VTC-2018 Fall), 5 pages, 6 figure

A Universal Receiver for Uplink NOMA Systems

Given its capability in efficient radio resource sharing, non-orthogonal multiple access (NOMA) has been identified as a promising technology in 5G to improve the system capacity, user connectivity, and scheduling latency. A dozen of uplink NOMA schemes have been proposed recently and this paper considers the design of a universal receiver suitable for all potential designs of NOMA schemes. Firstly, a general turbo-like iterative receiver structure is introduced, under which, a universal expectation propagation algorithm (EPA) detector with hybrid parallel interference cancellation (PIC) is proposed (EPA in short). Link-level simulations show that the proposed EPA receiver can achieve superior block error rate (BLER) performance with implementation friendly complexity and fast convergence, and is always better than the traditional codeword level MMSE-PIC receiver for various kinds of NOMA schemes.Comment: This paper has been accepted by IEEE/CIC International Conference on Communications in China (ICCC 2018). 5 pages, 4 figure

Increased gene copy number of DEFA1/DEFA3 worsens sepsis by inducing endothelial pyroptosis.

Sepsis claims an estimated 30 million episodes and 6 million deaths per year, and treatment options are rather limited. Human neutrophil peptides 1-3 (HNP1-3) are the most abundant neutrophil granule proteins but their neutrophil content varies because of unusually extensive gene copy number polymorphism. A genetic association study found that increased copy number of the HNP-encoding gene DEFA1/DEFA3 is a risk factor for organ dysfunction during sepsis development. However, direct experimental evidence demonstrating that these risk alleles are pathogenic for sepsis is lacking because the genes are present only in some primates and humans. Here, we generate DEFA1/DEFA3 transgenic mice with neutrophil-specific expression of the peptides. We show that mice with high copy number of DEFA1/DEFA3 genes have more severe sepsis-related vital organ damage and mortality than mice with low copy number of DEFA1/DEFA3 or wild-type mice, resulting from more severe endothelial barrier dysfunction and endothelial cell pyroptosis after sepsis challenge. Mechanistically, HNP-1 induces endothelial cell pyroptosis via P2X7 receptor-mediating canonical caspase-1 activation in a NLRP3 inflammasome-dependent manner. Based on these findings, we engineered a monoclonal antibody against HNP-1 to block the interaction with P2X7 and found that the blocking antibody protected mice carrying high copy number of DEFA1/DEFA3 from lethal sepsis. We thus demonstrate that DEFA1/DEFA3 copy number variation strongly modulates sepsis development in vivo and explore a paradigm for the precision treatment of sepsis tailored by individual genetic information

Connectivity, Connectivity, Connectivity: Has the China-Europe Freight Train Become a Winning Run?

In “China and Europe: Reconnecting across a New Silk Road” (Xiangming Chen and Julie Mardeusz ’16, The European Financial Review, February/March 2015), we included a short section about the China-Europe Freight Train (CEFT). The CEFT was then in its fourth year of running, while the Belt and Road Initiative (BRI) was officially only two years old. A total of 815 freight trains ran between China and Europe in 2015. The pandemic year of 2020 saw 12,406 trains between China and Europe, with another surge during the first six months of 2021. What has changed over a few short years? This article addresses this question by examining the scope of the CEFT’s connectivity and its impact on both ends of a transcontinental rail freight system across Eurasia

Globalization Redux: Can China’s Inside-Out Strategy Catalyze Economic Development Across Its Asian Borderlands and Beyond [post-print]

As the narrative of globalization in crisis heats up, China has stepped up as a new champion of globalization with its Belt and Road Initiative (BRI). This article repositions ‘China in the Global South’ to the front and center of the globalization discourse. Through a triangular framework, I differentiate and reconnect the three ‘master’ processes of urbanization, development and globalization to understand the inside-outside connections between China’s domestic transformation and strong impact in the Global South. Using China vs. Southeast Asia and Central Asia, I evaluate if and how China’s inside-out strategy can catalyze mutually beneficial development across some Asian borderlands and beyond

CORRIDOR-ISING IMPACT ALONG THE BELT AND ROAD: Is the Newly Operational China-Laos Railway a Game-Changer?

On 3 December 2021, amid the global surge of the Omicron variant, the China-Laos Railway (CLR), under construction since 2016, launched its maiden run from and toward its two termini at Kunming, capital city of Yunnan province in south-western China, and Vientiane, capital city of Laos. In more ways than one, the CLR is an unprecedented cross-border rail project in terms of scale, length, connected places, construction type, and potentially massive regional impact. These features exemplify the growing influence of the Belt and Road Initiative (BRI) along its six large-scale economic corridors and their key sub-corridors. In this essay, I explore the connective effects of the CLR using combined evidence on its late construction and early operation to illustrate the BRI’s broader “corridor-ising” impact

Globalisation redux: can China’s inside-out strategy catalyse economic development and integration across its Asian borderlands and beyond? [post-print]

As the narrative of globalisation in crisis heats up, China has stepped up as a new champion of globalisation with its ‘Belt and Road Initiative’. This article repositions ‘China in the Global South’ to the front and centre of the globalisation discourse. Through a triangular framework, I differentiate and reconnect the three ‘master’ processes of urbanisation, development and globalisation to understand the inside-outside connections between China’s domestic transformation and strong impact in the Global South. Using China vs Southeast Asia and Central Asia, I document how China’s westward development has created new development opportunities for its overland neighbours and beyond

China and the Middle East: More Than Oil

China has spread its ties to the Middle East in ways that go beyond oil. Below, Abbās Varij Kāzemi and Xiangming Chen argue that the Middle East is an important region to watch to gain a sense of China’s next moves globally

China\u27s Key Cities: From Local Places to Global Players

China’s geographically uneven growth plays a key role in regional integration by creating more varied and largely beneficial global connections. In this article, Xiangming Chen takes a new look at China’s key cities and how they not only drive China’s local and regional economic growth but also serve as bridges to link China’s varied local economies to regional and global markets