12,144 research outputs found
Determinants and Impacts of the Relative Use of Depository Receipts and Euro Convertible Bonds by High-tech Corporations: An Empirical Study
This paper adopts Taiwan's high-tech companies as the sample to address and examine four new determinants of various foreign financing instruments and test their impacts on the issuing firms. Our empirical findings are consistent with the following notions. First, the firms with higher foreign holding and foreign investment will be likely to adopt foreign financing policy. Moreover, the firms with higher stock dividend payment in Taiwan will adopt both of ECB (Euro convertible bond) and DR (depository receipt). Firm managers with better education background will prefer DR. Second, the use of DR can effectively decrease the volatility of stock returns but also pronounce a negative influence on the mean of stock returns. In contrast, the use of ECB can effectively increase the mean but can not significantly decrease the volatility.
Mixture Selection, Mechanism Design, and Signaling
We pose and study a fundamental algorithmic problem which we term mixture
selection, arising as a building block in a number of game-theoretic
applications: Given a function from the -dimensional hypercube to the
bounded interval , and an matrix with bounded entries,
maximize over in the -dimensional simplex. This problem arises
naturally when one seeks to design a lottery over items for sale in an auction,
or craft the posterior beliefs for agents in a Bayesian game through the
provision of information (a.k.a. signaling).
We present an approximation algorithm for this problem when
simultaneously satisfies two smoothness properties: Lipschitz continuity with
respect to the norm, and noise stability. The latter notion, which
we define and cater to our setting, controls the degree to which
low-probability errors in the inputs of can impact its output. When is
both -Lipschitz continuous and -stable, we obtain an (additive)
PTAS for mixture selection. We also show that neither assumption suffices by
itself for an additive PTAS, and both assumptions together do not suffice for
an additive FPTAS.
We apply our algorithm to different game-theoretic applications from
mechanism design and optimal signaling. We make progress on a number of open
problems suggested in prior work by easily reducing them to mixture selection:
we resolve an important special case of the small-menu lottery design problem
posed by Dughmi, Han, and Nisan; we resolve the problem of revenue-maximizing
signaling in Bayesian second-price auctions posed by Emek et al. and Miltersen
and Sheffet; we design a quasipolynomial-time approximation scheme for the
optimal signaling problem in normal form games suggested by Dughmi; and we
design an approximation algorithm for the optimal signaling problem in the
voting model of Alonso and C\^{a}mara
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Regulation of axon repulsion by MAX-1 SUMOylation and AP-3.
During neural development, growing axons express specific surface receptors in response to various environmental guidance cues. These axon guidance receptors are regulated through intracellular trafficking and degradation to enable navigating axons to reach their targets. In Caenorhabditis elegans, the UNC-5 receptor is necessary for dorsal migration of developing motor axons. We previously found that MAX-1 is required for UNC-5-mediated axon repulsion, but its mechanism of action remained unclear. Here, we demonstrate that UNC-5-mediated axon repulsion in C. elegans motor axons requires both max-1 SUMOylation and the AP-3 complex β subunit gene, apb-3 Genetic interaction studies show that max-1 is SUMOylated by gei-17/PIAS1 and acts upstream of apb-3 Biochemical analysis suggests that constitutive interaction of MAX-1 and UNC-5 receptor is weakened by MAX-1 SUMOylation and by the presence of APB-3, a competitive interactor with UNC-5. Overexpression of APB-3 reroutes the trafficking of UNC-5 receptor into the lysosome for protein degradation. In vivo fluorescence recovery after photobleaching experiments shows that MAX-1 SUMOylation and APB-3 are required for proper trafficking of UNC-5 receptor in the axon. Our results demonstrate that SUMOylation of MAX-1 plays an important role in regulating AP-3-mediated trafficking and degradation of UNC-5 receptors during axon guidance
Optimization Study of Small-Scale Solar Membrane Distillation Desalination Systems (s-SMDDS)
[[abstract]]Membrane distillation (MD), which can utilize low-grade thermal energy, has been extensively studied for desalination. By incorporating solar thermal energy, the solar membrane distillation desalination system (SMDDS) is a potential technology for resolving energy and water resource problems. Small-scale SMDDS (s-SMDDS) is an attractive and viable option for the production of fresh water for small communities in remote arid areas. The minimum cost design and operation of s-SMDDS are determined by a systematic method, which involves a pseudo-steady-state approach for equipment sizing and dynamic optimization using overall system mathematical models. Two s-SMDDS employing an air gap membrane distillation module with membrane areas of 11.5 m2 and 23 m2 are analyzed. The lowest water production costs are 5.16/m3 for water production rates of 500 kg/day and 1000 kg/day, respectively. For these two optimal cases, the performance ratios are 0.85 and 0.91; the recovery ratios are 4.07% and 4.57%. The effect of membrane characteristics on the production cost is investigated. For the commercial membrane employed in this study, the increase of the membrane mass transfer coefficient up to two times is beneficial for cost reduction.[[notice]]補正完畢[[incitationindex]]SCI[[incitationindex]]EI[[booktype]]電子
Intestinal tuberculosis previously mistreated as Crohn’s disease and complicated with perforation: a case report and literature review
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