High Performance Liquid Chromatographic Analysis of Almotriptan Malate in Bulk and Tablets

Purpose: A simple RP-HPLC method has been developed and validated for the determination of almotriptan malate (ATM) in bulk and tablets. Methods: Chromatographic separation of ATM was achieved by using a Thermo Scientific C18 column. A Mobile phase containing a mixture of methanol, water and acetic acid (4:8:0.1 v/v) was pumped at the flow rate of 1 mL/min. Detection was performed at 227 nm. According to ICH guidelines, the method was validated. Results: The calibration curve was linear in the concentration range 5–60 μg/mL for the ATM with regression coefficient 0.9999. The method was precise with RSD <1.2%. Excellent recoveries of 99.60 - 100.80% proved the accuracy of the method. The limits of detection and quantification were found to be 0.025 and 0.075 μg/mL, respectively. Conclusion: The method was successfully applied for the quantification of ATM in tablets with acceptable accuracy and precision

FPGA based Data Hiding through Steganography

Nowadays, the information security has been the key factor in communications, computer systems, electronic commerce and data sharing. One of the well-known methods for procuring the security of shared information using carrier files is steganography. The carrier file can be discrete such as image, text, audio and video etc. Digital images are the most commonly used format among those due to the high capacity and availability frequency. The hidden data is stored in an indistinct carrier in image steganography, i.e the digital image is used as a cover image to mask the secret message known as stego image. Cryptography can be then adapted for increasing the security of the stego image. A zig-zag MSB-LSB slicing based steganographic algorithm is proposed in this paper for concealing a secret image in a cover image. Power report and device utilization summary of the algorithm is calculated and the output is demonstrated on the VGA screen using BASYS3 Field Programmable Gate Array (FPGA).</jats:p