2,441 research outputs found

    Public Opinion Supervision - A Case Study of Media Freedom in China

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    This paper, through the study of news coverage of a housing development and relocation scandal in Hunan province, explores the scope of freedom that media enjoy in the Mainland, focusing particularly on the phenomenon of “public opinion supervision.” The case chosen involved 1100 households and 7,000 people living in the small county of Jiahe. Though relocation projects are common in China, this project involved active and direct local government intervention, with officials bending the law and harassing the residents. Despite attempts by residents to solve the problems through administrative channels and legal means throughout the year of 2003, this was of no avail. As a last resort, the residents sought help from the media. In the short period between early May and early June of 2004, a media relay commenced. Through tacit co-ordination among local newspapers, Beijing news groups and the China Central Television (CCTV), the story was eventually covered. Public condemnation against local officials came pouring in and the fate of local residents was changed dramatically. Behind the glorious façade of victory, the pressure that journalists faced was enormous. To the journalists, the battle had not been won completely. In the process, law was manipulated to be used as an oppressive tool by the local officials. However, without legal intervention at the final stage, and intervention by higher officials, media coverage may not have its impact felt. To capture the above intricacies and dynamics, I interviewed the journalists, lawyers that were directly involved in the case, and sought the views of other journalists and academics in media studies. My argument, sadly, lies in the reality that freedom of the press is heavily dependant on the administrative rank of the media institutions, the rank of the target to be reported and the discretion of the Central Party. Press freedom is a highly volatile political game, a struggle inside and outside media institutions, with boundaries for each round set anew

    Proton pump inhibitors - a sting in the tale?

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    Observation of 'ghost' islands and surfactant effect of surface gallium atoms during GaN growth by molecular beam epitaxy

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    GaN (0001) films grown by molecular beam epitaxy (MBE) were studied using scanning tunneling microscopy (STM). 'Ghost' islands were observed on surfaces grown under excess Ga conditions. These ghost islands were associated to a metastable, intermediate nucleation state of the surface.published_or_final_versio

    Comparative study on the broadening of exciton luminescence linewidth due to phonon in zinc-blende and wurtzite GaN epilayers

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    The broadening of exciton luminescence linewidth due to phonon in zinc-blende and wurtzite GaN epilayers was discussed. The coupling parameters between exciton and acoustic and longitudinal optical phonons were obtained for both structures. The analysis showed that the coupling constants of both exciton-acoustic optial phonon coupling and exciton-longitudinal optical phonon coupling for zinc-blende GaN were almost twice as much as the corresponding values of wurtzite GaN.published_or_final_versio

    Diverse proteomic alterations in gastric adenocarcinoma

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    Gastric adenocarcinoma is one of the most common cancers in Asian countries including China. Although its incidence rates in the West are lower than that in Asia, gastric cancer is still a major health problem worldwide, being second only to lung cancers in the number of deaths it causes. Helicobacter pylori infection has been identified as the major pathogen, but the detailed pathogenesis of gastric carcinoma remains elusive. Due to the lack of suitable and specific biomarkers for early detection, most cases of the disease are diagnosed at late stages and the survival rate is low. In this study, we used a proteomic approach to globally analyze the protein profiles of paired surgical specimens of primary gastric adenocarcinoma and nontumor mucosa aiming at identifying specific disease-associated proteins as potential clinical biomarkers and for carcinogenetic study. Compared to nontumor tissues, multiple protein alterations were found in tumor tissues. Some of these alterations involve variations in the expression of cytoskeleton proteins, including an increase in cytokeratin 8 and tropomyosin isoform and a decrease in cytokeratin 20. Co-up-regulations of heat-shock proteins and glycolytic enzymes were observed in tumor tissues, indicating self-protective efforts of cells and the growing energy requirement during malignant transformation. Diverse regulations also occurred with proteins involved in cell proliferation and differentiation, such as GMP reductase 2 and creatine kinase B, and proteins bearing potential tumor suppressor activities, including prohibitin and selenium binding protein 1. More interestingly, a human stomach-specific protein, 18 kDa antrum mucosa protein, was found to be dramatically under-expressed in cancer tissues, implicating a possible special pathological role for this protein in gastric carcinogenesis. Further comprehensive evaluation by globally considering the altered factors may result in the discovery of a biomarker index for effective assessment of the disease and may provide in-depth information for better understanding the pathogenesis of gastric cancer.postprin

    Left ventricular myocardial deformation and mechanical dyssynchrony in children with normal ventricular shortening fraction after anthracycline therapy

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    Objective: The M-mode-derived left ventricular shortening fraction is incorporated into most of the paediatric oncology protocols for monitoring of cardiotoxicity. This study tested the hypothesis that alteration of left ventricular myocardial deformation and mechanical dyssynchrony may occur in asymptomatic children after anthracycline therapy despite having left ventricular shortening fractions within the limits of normal. Design: Cross-sectional study. Setting: Tertiary paediatric cardiac centre. Methods: Left ventricular longitudinal, circumferential and radial myocardial deformation was determined using speckle tracking echocardiography in 45 patients aged 15.3±5.8 years. Real-time three-dimensional echocardiographic data were acquired for the measurement of left ventricular volumes and systolic dyssynchrony index (SDI), the latter derived from the dispersion of time-to-minimum regional volume using a 16-segment model. The results were compared with those of 44 controls. Results: Compared with controls, patients had reduced left ventricular global systolic longitudinal strain (p=0.012), circumferential strain (p4.96%) in patients was 16% (95% CI 6% to 29%). In patients, SDI correlated negatively with left ventricular ejection fraction (r=-0.52, p<0.001), radial strain (r=-0.35, p=0.021), circumferential strain (r=-0.37, p=0.015) and circumferential SR (r=-0.43, p=0.004), but not with the cumulative anthracycline dose (p=0.82). Conclusions: Impaired left ventricular myocardial deformation and mechanical dyssynchrony may exist in children after anthracycline therapy despite having normal left ventricular shortening fractions.published_or_final_versio

    Initial stage of GaN growth and its implication to defect formation in films

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    In situ scanning tunneling microscopy (STM) observations of initial growth processes of GaN by molecularbeam epitaxy reveal important differences between growth on vicinal versus flat SiC(0001) substrates. Based on stop-growth STM studies, we explain why there are orders of magnitude reductions in the density of threading screw dislocations in the vicinal films. It is shown that on vicinal surfaces, three-dimensional (3D) islands develop into a characteristic shape. The islands coalesce much sooner than on flat surfaces. Consequently, fewer defects are created at their boundaries.published_or_final_versio

    Neuroprotective effects of minocycline on double-stranded RNA-induced neurotoxicity in cultured cortical neurons

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    1. Minocycline, memantine,and glycoconjugate were assessed for their ability to protect cultured primary cortical neurons against double-stranded RNA-induced neurotoxicity. 2. Minocycline but not memantine or glycoconjugate protected cultured cells and warrants further investigation.published_or_final_versio
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