Feedback Cooling of a Single Neutral Atom

We demonstrate feedback cooling of the motion of a single rubidium atom trapped in a high-finesse optical resonator to a temperature of about 160 \mu K. Time-dependent transmission and intensity-correlation measurements prove the reduction of the atomic position uncertainty. The feedback increases the 1/e storage time into the one second regime, 30 times longer than without feedback. Feedback cooling therefore rivals state-of-the-art laser cooling, but with the advantages that it requires less optical access and exhibits less optical pumping.Comment: 5 pages, 4 figure

Integrating the common variability language with multilanguage annotations for web engineering

Web applications development involves managing a high diversity of files and resources like code, pages or style sheets, implemented in different languages. To deal with the automatic generation of custom-made configurations of web applications, industry usually adopts annotation-based approaches even though the majority of studies encourage the use of composition-based approaches to implement Software Product Lines. Recent work tries to combine both approaches to get the complementary benefits. However, technological companies are reticent to adopt new development paradigms such as feature-oriented programming or aspect-oriented programming. Moreover, it is extremely difficult, or even impossible, to apply these programming models to web applications, mainly because of their multilingual nature, since their development involves multiple types of source code (Java, Groovy, JavaScript), templates (HTML, Markdown, XML), style sheet files (CSS and its variants, such as SCSS), and other files (JSON, YML, shell scripts). We propose to use the Common Variability Language as a composition-based approach and integrate annotations to manage fine grained variability of a Software Product Line for web applications. In this paper, we (i) show that existing composition and annotation-based approaches, including some well-known combinations, are not appropriate to model and implement the variability of web applications; and (ii) present a combined approach that effectively integrates annotations into a composition-based approach for web applications. We implement our approach and show its applicability with an industrial real-world system.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Stress hormones: cortisol, adrenocorticotropic hormone and oxytocin in the context of social violations in children with autism spectrum disorders

Autism spectrum disorders (ASD) refer to heterogeneous disorders of neurodevelopment, the main symptom of which is social insufficiency. Aim: to conduct a one-stage assessment of the relationship between key hormones in the regulation of social and stress responses: adrenocorticotropic hormone (ACTH), cortisol, oxytocin, in children with ASD in the context of severe social insufficiency. Materials and methods. A total of 44 children (37 boys and 7 girls) aged 3 to 12 years with a diagnosis of ASD were examined, which were divided into groups: with preserved social contact / lack of it. The concentrations of hormones were evaluated in blood plasma by the method of ELISA. Results. ACTH and cortisol demonstrate interdependent relationships without the involvement of oxytocin in children with ASD, while maintaining their social contact. In children with ASD with symptoms of social insufficiency, there are no correlations between the studied neurohormones. The conclusion. The data obtained suggest that the processes of disorganization / destruction of neuroanatomical and physiological connections between the systems of oxytocin and the hypothalamic-pituitary-adrenal axis (HPA-axis) and (or) the hypothalamic-neurohypophysis system and the HPA-axis