2,285 research outputs found

    Investigating students seriousness during selected conceptual inventory surveys

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    Conceptual inventory surveys are routinely used in education research to identify student learning needs and assess instructional practices. Students might not fully engage with these instruments because of the low stakes attached to them. This paper explores tests that can be used to estimate the percentage of students in a population who might not have taken such surveys seriously. These three seriousness tests are the pattern recognition test, the easy questions test, and the uncommon answers test. These three tests are applied to sets of students who were assessed either by the Force Concept Inventory, the Conceptual Survey of Electricity and Magnetism, or the Brief Electricity and Magnetism Assessment. The results of our investigation are compared to computer simulated populations of random answers.Comment: 8 pages; submitted to Phys Rev PE

    Reconceptualising Legal Education after War

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    This paper considers the impact of war on legal education and assesses the contributions of legal education to post-conflict reconstruction and reconciliation

    Luminosity Function of Faint Globular Clusters in M87

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    We present the luminosity function to very faint magnitudes for the globular clusters in M87, based on a 30 orbit \textit{Hubble Space Telescope (HST)} WFPC2 imaging program. The very deep images and corresponding improved false source rejection allow us to probe the mass function further beyond the turnover than has been done before. We compare our luminosity function to those that have been observed in the past, and confirm the similarity of the turnover luminosity between M87 and the Milky Way. We also find with high statistical significance that the M87 luminosity function is broader than that of the Milky Way. We discuss how determining the mass function of the cluster system to low masses can constrain theoretical models of the dynamical evolution of globular cluster systems. Our mass function is consistent with the dependence of mass loss on the initial cluster mass given by classical evaporation, and somewhat inconsistent with newer proposals that have a shallower mass dependence. In addition, the rate of mass loss is consistent with standard evaporation models, and not with the much higher rates proposed by some recent studies of very young cluster systems. We also find that the mass-size relation has very little slope, indicating that there is almost no increase in the size of a cluster with increasing mass.Comment: 22 pages, 5 figures, Accepted for publication in Ap

    Ultraviolet HST Observations of the Jet in M87

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    We present new ultraviolet photometry of the jet in M87 obtained from HST WFPC2 imaging. We combine these ultraviolet data with previously published photometry for the knots of the jet in radio, optical, and X-ray, and fit three theoretical synchrotron models to the full data set. The synchrotron models consistently overpredict the flux in the ultraviolet when fit over the entire dataset. We show that if the fit is restricted to the radio through ultraviolet data, the synchrotron models can provide a good match to the data. The break frequencies of these fits are much lower than previous estimates. The implied synchrotron lifetimes for the bulk of the emitting population are longer than earlier work, but still much shorter than the estimated kinematic lifetimes of the knots. The observed X-ray flux cannot be successfully explained by the simple synchrotron models that fit the ultraviolet and optical fluxes. We discuss the possible implications of these results for the physical properties of the M87 jet. We also observe increased flux for the HST-1 knot that is consistent with previous results for flaring. This observation fills in a significant gap in the time coverage early in the history of the flare, and therefore sets constraints on the initial brightening of the flare.Comment: 14 pages, 2 figures, Accepted for publication in ApJ, changed lightcurve and caption in Figure

    STING-dependent recognition of cyclic di-AMP mediates type I interferon responses during Chlamydia trachomatis infection.

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    UnlabelledSTING (stimulator of interferon [IFN] genes) initiates type I IFN responses in mammalian cells through the detection of microbial nucleic acids. The membrane-bound obligate intracellular bacterium Chlamydia trachomatis induces a STING-dependent type I IFN response in infected cells, yet the IFN-inducing ligand remains unknown. In this report, we provide evidence that Chlamydia synthesizes cyclic di-AMP (c-di-AMP), a nucleic acid metabolite not previously identified in Gram-negative bacteria, and that this metabolite is a prominent ligand for STING-mediated activation of IFN responses during infection. We used primary mouse lung fibroblasts and HEK293T cells to compare IFN-β responses to Chlamydia infection, c-di-AMP, and other type I IFN-inducing stimuli. Chlamydia infection and c-di-AMP treatment induced type I IFN responses in cells expressing STING but not in cells expressing STING variants that cannot sense cyclic dinucleotides but still respond to cytoplasmic DNA. The failure to induce a type I IFN response to Chlamydia and c-di-AMP correlated with the inability of STING to relocalize from the endoplasmic reticulum to cytoplasmic punctate signaling complexes required for IFN activation. We conclude that Chlamydia induces STING-mediated IFN responses through the detection of c-di-AMP in the host cell cytosol and propose that c-di-AMP is the ligand predominantly responsible for inducing such a response in Chlamydia-infected cells.ImportanceThis study shows that the Gram-negative obligate pathogen Chlamydia trachomatis, a major cause of pelvic inflammatory disease and infertility, synthesizes cyclic di-AMP (c-di-AMP), a nucleic acid metabolite that thus far has been described only in Gram-positive bacteria. We further provide evidence that the host cell employs an endoplasmic reticulum (ER)-localized cytoplasmic sensor, STING (stimulator of interferon [IFN] genes), to detect c-di-AMP synthesized by Chlamydia and induce a protective IFN response. This detection occurs even though Chlamydia is confined to a membrane-bound vacuole. This raises the possibility that the ER, an organelle that innervates the entire cytoplasm, is equipped with pattern recognition receptors that can directly survey membrane-bound pathogen-containing vacuoles for leaking microbe-specific metabolites to mount type I IFN responses required to control microbial infections

    The Annual Economic Survey of Federal Gulf Shrimp Permit Holders: Report on the Design, Implementation, and Descriptive Results for 2006

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    This technical memorandum documents the design, implementation, data preparation, and descriptive results for the 2006 Annual Economic Survey of Federal Gulf Shrimp Permit Holders. The data collection was designed by the NOAA Fisheries Southeast Fisheries Science Center Social Science Research Group to track the financial and economic status and performance by vessels holding a federal moratorium permit for harvesting shrimp in the Gulf of Mexico. A two page, self-administered mail survey collected total annual costs broken out into seven categories and auxiliary economic data. In May 2007, 580 vessels were randomly selected, stratified by state, from a preliminary population of 1,709 vessels with federal permits to shrimp in offshore waters of the Gulf of Mexico. The survey was implemented during the rest of 2007. After many reminder and verification phone calls, 509 surveys were deemed complete, for an ineligibility-adjusted response rate of 90.7%. The linking of each individual vessel’s cost data to its revenue data from a different data collection was imperfect, and hence the final number of observations used in the analyses is 484. Based on various measures and tests of validity throughout the technical memorandum, the quality of the data is high. The results are presented in a standardized table format, linking vessel characteristics and operations to simple balance sheet, cash flow, and income statements. In the text, results are discussed for the total fleet, the Gulf shrimp fleet, the active Gulf shrimp fleet, and the inactive Gulf shrimp fleet. Additional results for shrimp vessels grouped by state, by vessel characteristics, by landings volume, and by ownership structure are available in the appendices. The general conclusion of this report is that the financial and economic situation is bleak for the average vessels in most of the categories that were evaluated. With few exceptions, cash flow for the average vessel is positive while the net revenue from operations and the “profit” are negative. With negative net revenue from operations, the economic return for average shrimp vessels is less than zero. Only with the help of government payments does the average owner just about break even. In the short-term, this will discourage any new investments in the industry. The financial situation in 2006, especially if it endures over multiple years, also is economically unsustainable for the average established business. Vessels in the active and inactive Gulf shrimp fleet are, on average, 69 feet long, weigh 105 gross tons, are powered by 505 hp motor(s), and are 23 years old. Three-quarters of the vessels have steel hulls and 59% use a freezer for refrigeration. The average market value of these vessels was 175,149in2006,aboutahundredthousanddollarslessthantheaverageoriginalpurchaseprice.Theoutstandingloansaveraged175,149 in 2006, about a hundred-thousand dollars less than the average original purchase price. The outstanding loans averaged 91,955, leading to an average owner equity of 83,194.Basedonthesample,85owneroperated.Onaverage,thesevesselsburned52,931gallonsoffuel,landed101,268poundsofshrimp,andreceived83,194. Based on the sample, 85% of the federally permitted Gulf shrimp fleet was actively shrimping in 2006. Of these 386 active Gulf shrimp vessels, just under half (46%) were owner-operated. On average, these vessels burned 52,931 gallons of fuel, landed 101,268 pounds of shrimp, and received 2.47 per pound of shrimp. Non-shrimp landings added less than 1% to cash flow, indicating that the federal Gulf shrimp fishery is very specialized. The average total cash outflow was 243,415ofwhich243,415 of which 108,775 was due to fuel expenses alone. The expenses for hired crew and captains were on average 54,866whichindicatestheimportanceoftheindustryasasourceofwageincome.Theresultingaveragenetcashflowis54,866 which indicates the importance of the industry as a source of wage income. The resulting average net cash flow is 16,225 but has a large standard deviation. For the population of active Gulf shrimp vessels we can state with 95% certainty that the average net cash flow was between 9,500and9,500 and 23,000 in 2006. The median net cash flow was 11,843.BasedontheincomestatementforactiveGulfshrimpvessels,theaveragefixedcostsaccountedforjustunderaquarterofoperatingexpenses(23.1Theaveragelaborcontribution(ascaptain)ofanowneroperatorisestimatedatabout11,843. Based on the income statement for active Gulf shrimp vessels, the average fixed costs accounted for just under a quarter of operating expenses (23.1%), labor costs for just over a quarter (25.3%), and the non-labor variable costs for just over half (51.6%). The fuel costs alone accounted for 42.9% of total operating expenses in 2006. It should be noted that the labor cost category in the income statement includes both the actual cash payments to hired labor and an estimate of the opportunity cost of owner-operators’ time spent as captain. The average labor contribution (as captain) of an owner-operator is estimated at about 19,800. The average net revenue from operations is negative 7,429,andisstatisticallydifferentandlessthanzeroinspiteofalargestandarddeviation.TheeconomicreturntoGulfshrimpingisnegative47,429, and is statistically different and less than zero in spite of a large standard deviation. The economic return to Gulf shrimping is negative 4%. Including non-operating activities, foremost an average government payment of 13,662, leads to an average loss before taxes of 907forthevesselowners.Theconfidenceintervalofthisvaluestraddleszero,sowecannotreject,with95TheaverageinactiveGulfshrimpvesselisgenerallyofasmallerscalethantheaverageactivevessel.Inactivevesselsarephysicallysmaller,arevaluedmuchlower,andarelessdependentonloans.Fixedcostsaccountfornearlythreequartersofthetotaloperatingexpensesof907 for the vessel owners. The confidence interval of this value straddles zero, so we cannot reject, with 95% certainty, that the population average is zero. The average inactive Gulf shrimp vessel is generally of a smaller scale than the average active vessel. Inactive vessels are physically smaller, are valued much lower, and are less dependent on loans. Fixed costs account for nearly three quarters of the total operating expenses of 11,926, and only 6% of these vessels have hull insurance. With an average net cash flow of negative 7,537,theinactiveGulfshrimpfleethasamajorliquidityproblem.Onaverage,netrevenuefromoperationsisnegative7,537, the inactive Gulf shrimp fleet has a major liquidity problem. On average, net revenue from operations is negative 11,396, which amounts to a negative 15% economic return, and owners lose 9,381ontheirvesselsbeforetaxes.Tosustainsuchlossesandespeciallytosurvivethenegativecashflow,manyoftheownersmustbesubsidizingtheirshrimpvesselswiththehelpofotherincomeorwealthsourcesoraredrawingdowntheirequity.ActiveGulfshrimpvesselsinallstatesbutTexasexhibitednegativereturns.TheAlabamaandMississippifleetshavethehighestassets(vesselvalues),onaverage,yettheygeneratezerocashflowandnegative9,381 on their vessels before taxes. To sustain such losses and especially to survive the negative cash flow, many of the owners must be subsidizing their shrimp vessels with the help of other income or wealth sources or are drawing down their equity. Active Gulf shrimp vessels in all states but Texas exhibited negative returns. The Alabama and Mississippi fleets have the highest assets (vessel values), on average, yet they generate zero cash flow and negative 32,224 net revenue from operations. Due to their high (loan) leverage ratio the negative 11% economic return is amplified into a negative 21% return on equity. In contrast, for Texas vessels, which actually have the highest leverage ratio among the states, a 1% economic return is amplified into a 13% return on equity. From a financial perspective, the average Florida and Louisiana vessels conform roughly to the overall average of the active Gulf shrimp fleet. It should be noted that these results are averages and hence hide the variation that clearly exists within all fleets and all categories. Although the financial situation for the average vessel is bleak, some vessels are profitable. (PDF contains 101 pages

    Contextual organismality: Beyond pattern to process in the emergence of organisms

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    Biologists have taken the concept of organism largely for granted. However, advances in the study of chimerism, symbiosis, bacterial-eukaryote associations, and microbial behavior have prompted a redefinition of organisms as biological entities exhibiting low conflict and high cooperation among their parts. This expanded view identifies organisms in evolutionary time. However, the ecological processes, mechanisms, and traits that drive the formation of organisms remain poorly understood. Recognizing that organismality can be context dependent, we advocate elucidating the ecological contexts under which entities do or do not act as organisms. Here we develop a "contextual organismality" framework and provide examples of entities, such as honey bee colonies, tumors, and bacterial swarms, that can act as organisms under specific life history, resource, or other ecological circumstances. We suggest that context dependence may be a stepping stone to the development of increased organismal unification, as the most integrated biological entities generally show little context dependence. Recognizing that organismality is contextual can identify common patterns and testable hypotheses across different entities. The contextual organismality framework can illuminate timeless as well as pressing issues in biology, including topics as disparate as cancer emergence, genomic conflict, evolution of symbiosis, and the role of the microbiota in impacting host phenotype.John Templeton FoundationVersion of record online: 27 October 2016; published open access.This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]

    A Gaia-PS1-SDSS (GPS1) Proper Motion Catalog Covering 3/4 of the Sky

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    We combine Gaia DR1, PS1, SDSS and 2MASS astrometry to measure proper motions for 350 million sources across three-fourths of the sky down to a magnitude of mr20m_r\sim20\,. Using positions of galaxies from PS1, we build a common reference frame for the multi-epoch PS1, single-epoch SDSS and 2MASS data, and calibrate the data in small angular patches to this frame. As the Gaia DR1 excludes resolved galaxy images, we choose a different approach to calibrate its positions to this reference frame: we exploit the fact that the proper motions of stars in these patches are {\it linear}. By simultaneously fitting the positions of stars at different epochs of -- Gaia DR1, PS1, SDSS, and 2MASS -- we construct an extensive catalog of proper motions dubbed GPS1. GPS1 has a characteristic systematic error of less than 0.3 \masyr\, and a typical precision of 1.52.0 1.5-2.0\masyr. The proper motions have been validated using galaxies, open clusters, distant giant stars and QSOs. In comparison with other published faint proper motion catalogs, GPS1's systematic error (<0.3<0.3 \masyr) should be nearly an order of magnitude better than that of PPMXL and UCAC4 (>2.0>2.0 \masyr). Similarly, its precision (1.5\sim 1.5 \masyr) is a four-fold improvement relative to PPMXL and UCAC4 (6.0\sim 6.0 \masyr). For QSOs, the precision of GPS1 is found to be worse (2.03.0\sim 2.0-3.0\masyr), possibly due to their particular differential chromatic refraction (DCR). The GPS1 catalog will be released on-line and available via the VizieR Service and VO Service. (===GPS1 is available with VO TAP Query now, see http://www2.mpia-hd.mpg.de/~tian/GPS1/ for details=== )Comment: 17 pages, 19 figures, published on-line in ApJS (GPS1 is available with VO TAP Query now

    Spatially resolved spectroscopy of the globular cluster RZ 2109 and the nature of its black hole

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    We present optical HST/STIS spectroscopy of RZ 2109, a globular cluster in the elliptical galaxy NGC 4472. This globular cluster is notable for hosting an ultraluminous X-ray source as well as associated strong and broad [OIII] 4959, 5007 emission. We show that the HST/STIS spectroscopy spatially resolves the [OIII] emission in RZ 2109. While we are unable to make a precise determination of the morphology of the emission line nebula, the best fitting models all require that the [OIII] 5007 emission has a half light radius in the range 3-7 pc. The extended nature of the [OIII] 5007 emission is inconsistent with published models that invoke an intermediate mass black hole origin. It is also inconsistent with the ionization of ejecta from a nova in the cluster. The spatial scale of the nebula could be produced via the photoionization of a strong wind driven from a stellar mass black hole accreting at roughly its Eddington rate.Comment: 7 pages, 4 figures - accepted for publication in Ap
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