Cost effectiveness of thrombolytic therapy with tissue plasminogen activator as compared with streptokinase for acute myocardial infarction

BACKGROUND. Patients with acute myocardial infarction who were treated with accelerated tissue plasminogen activator (t-PA) (given over a period of 1 1/2 hours rather than the conventional 3 hours, and with two thirds of the dose given in the first 30 minutes) had a 30-day mortality that was 15 percent lower than that of pati

Quantum dots coordinated with conjugated organic ligands: new nanomaterials with novel photophysics

CdSe quantum dots functionalized with oligo-(phenylene vinylene) (OPV) ligands (CdSe-OPV nanostructures) represent a new class of composite nanomaterials with significantly modified photophysics relative to bulk blends or isolated components. Single-molecule spectroscopy on these species have revealed novel photophysics such as enhanced energy transfer, spectral stability, and strongly modified excited state lifetimes and blinking statistics. Here, we review the role of ligands in quantum dot applications and summarize some of our recent efforts probing energy and charge transfer in hybrid CdSe-OPV composite nanostructures

The geopolitical economy of Thailand’s marine plasticpollution crisis

Currently approximately 9 million tons of plastic enter the world’s oceans annually. This is a majortransboundary problem on a global scale that threatens marine wildlife, coastal ecologies, human health andlivelihoods. Our concern in this paper is with the environmental governance of marine plastic pollution thatemanates from Thailand, the sixth biggest contributor globally. By zooming in on land-based polluters inThailand, we highlight both the systemic nature of the marine plastic problem and the relative impunity withwhich drivers of transboundary environmental harm function at all levels of governance. Drawing from 19 inter-views conducted with actors from the public, private and non-profit sectors, we examine three stages of theproblem: production, consumption and waste management. We found that three major barriers preventThailand’s government, private sector and citizens from engaging in the sort collective action needed to reducemarine plastic pollution. They are: (i) insufficient incentives to enact political change; (ii) scalar disconnects inwaste management; and (iii) inadequate public and private sector ownership over plastic waste reduction. Asthe state alone cannot change corporate and consumer behaviour, we argue that multi-stakeholder efforts acrossorganisational scales of governance and administrative boundaries are needed to address the barrier

Scale issues in soil moisture modelling: problems and prospects

Soil moisture storage is an important component of the hydrological cycle and plays a key role in land-surface-atmosphere interaction. The soil-moisture storage equation in this study considers precipitation as an input and soil moisture as a residual term for runoff and evapotranspiration. A number of models have been developed to estimate soil moisture storage and the components of the soil-moisture storage equation. A detailed discussion of the impli cation of the scale of application of these models reports that it is not possible to extrapolate processes and their estimates from the small to the large scale. It is also noted that physically based models for small-scale applications are sufficiently detailed to reproduce land-surface- atmosphere interactions. On the other hand, models for large-scale applications oversimplify the processes. Recently developed physically based models for large-scale applications can only be applied to limited uses because of data restrictions and the problems associated with land surface characterization. It is reported that remote sensing can play an important role in over coming the problems related to the unavailability of data and the land surface characterization of large-scale applications of these physically based models when estimating soil moisture storage.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline