Immersive learning research

Editorial. Material for the special issue "Immersive Learning Research" of the Journal of Universal Computer Science.Welcome to the Journal of Universal Computer Science (J.UCS) special issue organized by the Immersive Learning Research Network (iLRN) following the 2017 iLRN conference. This issue includes eight papers on the focused topic "Immersive Learning Research", including extended versions of papers presented at iLRN 2017 and articles from the public call for papers.info:eu-repo/semantics/publishedVersio

Aerosolizable marine phycotoxins and human health effects : in vitro support for the biogenics hypothesis

Respiratory exposure to marine phycotoxins is of increasing concern. Inhalation of sea spray aerosols (SSAs), during harmful Karenia brevis and Ostreopsis ovata blooms induces respiratory distress among others. The biogenics hypothesis, however, suggests that regular airborne exposure to natural products is health promoting via a downregulation of the mechanistic target of rapamycin (mTOR) pathway. Until now, little scientific evidence supported this hypothesis. The current explorative in vitro study investigated both health-affecting and potential health-promoting mechanisms of airborne phycotoxin exposure, by analyzing cell viability effects via cytotoxicity assays and effects on the mTOR pathway via western blotting. To that end, A549 and BEAS-2B lung cells were exposed to increasing concentrations (ng·L−1 – mg·L−1) of (1) pure phycotoxins and (2) an extract of experimental aerosolized homoyessotoxin (hYTX). The lowest cell viability effect concentrations were found for the examined yessotoxins (YTXs). Contradictory to the other phycotoxins, these YTXs only induced a partial cell viability decrease at the highest test concentrations. Growth inhibition and apoptosis, both linked to mTOR pathway activity, may explain these effects, as both YTXs were shown to downregulate this pathway. This proof-of-principle study supports the biogenics hypothesis, as specific aerosolizable marine products (e.g., YTXs) can downregulate the mTOR pathway

Eating As Treatment (EAT): A Stepped-Wedge, Randomized Controlled Trial of a Health Behavior Change Intervention Provided by Dietitians to Improve Nutrition in Patients With Head and Neck Cancer Undergoing Radiation Therapy (TROG 12.03)

Purpose: Malnutrition in head and neck cancer (HNC) treatment is common and associated with poorer morbidity and mortality outcomes. This trial aimed to improve nutritional status during radiation therapy (RT) using a novel method of training dietitians to deliver psychological techniques to improve nutritional behaviors in patients with HNC. Methods and Materials: This trial used a stepped-wedge, randomized controlled design to assess the efficacy of the Eating As Treatment (EAT) program. Based on motivational interviewing and cognitive behavioral therapy, EAT was designed to be delivered by oncology dietitians and integrated into their clinical practice. During control steps, dietitians provided treatment as usual, before being trained in EAT and moving into the intervention phase. The training was principles based and sought to improve behavior-change skills rather than provide specific scripts. Patients recruited to the trial (151 controls, 156 intervention) were assessed at 4 time points (the first and the final weeks of RT, and 4 and 12 weeks afterward). The primary outcome was nutritional status at the end of RT as measured by the Patient-Generated Subjective Global Assessment. Results: Patients who received the EAT intervention had significantly better scores on the primary outcome of nutritional status at the critical end-of-treatment time point (β = −1.53 [−2.93 to −.13], P =.03). Intervention patients were also significantly more likely than control patients to be assessed as well-nourished at each time point, lose a smaller percentage of weight, have fewer treatment interruptions, present lower depression scores, and report a higher quality of life. Although results were not statistically significant, patients who received the intervention had fewer and shorter unplanned hospital admissions. Conclusions: This trial is the first of its kind to demonstrate the effectiveness of a psychological intervention to improve nutrition in patients with HNC who are receiving RT. The intervention provides a means to ameliorate malnutrition and the important related outcomes and consequently should be incorporated into standard care for patients receiving RT for HNC

The problem of globalization

There is a general consensus that the contemporary world is best under-stood through the prism of globalization. This view is shared by most social scientists, politicians, journalists, businesses, and indeed broad sectors of the general population. Opinions differ as to whether global-ization is a positive or a negative development, but there is general agreement that whatever is going on is either a symptom or a consequence of globalization. There are many good reasons for this view. The number of passengers on scheduled international flights has risen by a factor of six between 1975 and 2000. The number of international tourist arrivals rose by three and a half times during the same period. Much less happily, the number of internationally displaced refugees rose by around 50 percent in the 20 years before 2000. During the quarter of a century after 1975, the duration of international voice telephone calls rose by around 25 times. We could go on multiplying such striking figures i

Learning to program using immersive approaches: A case study learning SAS®, IBM Bluemix and Watson Analytics

Learning to program is an activity which needs the learner to develop a range of new skills. Traditionally, this has been achieved in Universities by a presenting a series of structured lectures and tutorials covering the syntax and grammar of the language. This approach often leads to disengagement by many of the weaker students. It is becoming clear that this may not be the most effective approach in the twenty first century as a result of the continuous development of software packages which leads to the need to continually revise the teaching materials. In addition, modern millennial students demand engaging modes of learning that al-so prepare them for employment. This paper evaluates an approach which pro-vides a directed, immersive learning approach that mirrors the real world of em-ployment, develops both the requisite technical skills together with the fundamen-tal soft skills necessary for employment and prepares the students for lifelong learning and development and maintenance of new skills and languages. It also provides an intensely engaging environment that allows students to demonstrate the wide range of technical and soft skills that are necessary for a successful ca-reer. This approach also leads to high levels of achievement from the students and reduces stress levels in the academics leading the courses. The approach should be applicable to most STEM subjects which require the use of specialist software packages

Modeling crop phenology using remotely sensed data

Timely monitoring and prediction of the trajectory of crop development provides scientific information to agronomists and climate scientists. For example, estimates of when crops reach certain growth stages can help estimate the length of the growing season or the timing of cessation of crop transpiration. The Soil Moisture and Ocean Salinity (SMOS) and Soil Moisture Active Passive (SMAP) satellites collect data at high spatial and temporal resolution compared to traditional remote sensing devices. In regions with intensive agriculture, such as Iowa, their measurements track the progression of crops through their growth stages. Using data products from these two satellites, we develop three modeling approaches to describe crop growth signatures over a collection of spatially referenced satellite footprints in Iowa. We first propose a state space model, followed by a nonlinear parametric hierarchical model, and lastly a functional modeling approach. In addition to describing the entire seasonal growth curve, we estimate, and provide uncertainty quantification, for the timing of when corn reaches its milk (R3) growth stage. Lastly, we develop forecasting methods to predict the timing of R3 mid-season when only partial data is available

V1647 Orionis: One Year into Quiescence

We present new optical, near-IR, and mid-IR observations of the young eruptive variable star V1647 Orionis that went into outburst in late 2004 for approximately two years. Our observations were taken one year after the star had faded to its pre-outburst optical brightness and show that V1647Ori is still actively accreting circumstellar material. We compare and contrast these data with existing observations of the source from both pre-outburst and outburst phases. From near-IR spectroscopy we identify photospheric absorption features for the first time that allow us to constrain the classification of the young star itself. Our best fit spectral type is M0+-2 sub-classes with a visual extinction of 19+-2 magnitudes and a K-band veiling of rK~1.5+-0.2. We estimate that V1647Ori has a quiescent bolometric luminosity of ~9.5Lsun and a mass accretion rate of ~1.10^-6Msun yr^-1. Our derived mass and age, from comparison with evolutionary models, are 0.8+-0.2 Msun and ~0.5Myrs, respectively. The presence towards the star of shock excited optical [S II] and [Fe II] emission as well as near-IR H2 and [Fe II] emission perhaps suggests that a new Herbig-Haro flow is becoming visible close to the star.Comment: 22 pages, 19 Figures, accepted AJ 13 October 200

V2494 cyg: A unique FU ori type object in the cygnus OB7 complex

A photometric and spectral study of the variable star V2494 Cyg in the L 1003 dark cloud is presented. The brightness of the star, formerly known as HH 381 IRS, increased by 2.5 mag in R (probably in the 1980s) and since then has remained nearly constant. Since the brightness increase, V2494 Cyg has illuminated a bipolar cometary nebula. The stellar spectrum has several features typical of the FU Ori (FUor) type, plus it exhibits very strong Ha and forbidden emissionlines with high-velocity components. These emission lines originate in the Herbig-Haro (HH) jet near the star. The kinematic age of the jet is consistent with it forming at the time of the outburst leading to the luminosity increase. V2494 Cyg also produces a rather extended outflow; it is the first known FUor with both an observed outburst and a parsec-sized HH flow. The nebula, illuminated by V2494 Cyg, possesses similar morphological and spectral characteristics to Hubble's variable nebula (R Monocerotis/NGC 2261). © 2013 The Authors Published by Oxford University Press on behalf of the Royal Astronomical Society

The Third wave in globalization theory

This essay examines a proposition made in the literature that there are three waves in globalization theory—the globalist, skeptical, and postskeptical or transformational waves—and argues that this division requires a new look. The essay is a critique of the third of these waves and its relationship with the second wave. Contributors to the third wave not only defend the idea of globalization from criticism by the skeptics but also try to construct a more complex and qualified theory of globalization than provided by first-wave accounts. The argument made here is that third-wave authors come to conclusions that try to defend globalization yet include qualifications that in practice reaffirm skeptical claims. This feature of the literature has been overlooked in debates and the aim of this essay is to revisit the literature and identify as well as discuss this problem. Such a presentation has political implications. Third wavers propose globalist cosmopolitan democracy when the substance of their arguments does more in practice to bolster the skeptical view of politics based on inequality and conflict, nation-states and regional blocs, and alliances of common interest or ideology rather than cosmopolitan global structures

Soil methane sink capacity response to a long-term wildfire chronosequence in Northern Sweden

Boreal forests occupy nearly one fifth of the terrestrial land surface and are recognised as globally important regulators of carbon (C) cycling and greenhouse gas emissions. Carbon sequestration processes in these forests include assimilation of CO2 into biomass and subsequently into soil organic matter, and soil microbial oxidation of methane (CH4). In this study we explored how ecosystem retrogression, which drives vegetation change, regulates the important process of soil CH4 oxidation in boreal forests. We measured soil CH4 oxidation processes on a group of 30 forested islands in northern Sweden differing greatly in fire history, and collectively representing a retrogressive chronosequence, spanning 5000 years. Across these islands the build-up of soil organic matter was observed to increase with time since fire disturbance, with a significant correlation between greater humus depth and increased net soil CH4 oxidation rates. We suggest that this increase in net CH4 oxidation rates, in the absence of disturbance, results as deeper humus stores accumulate and provide niches for methanotrophs to thrive. By using this gradient we have discovered important regulatory controls on the stability of soil CH4 oxidation processes that could not have not been explored through shorter-term experiments. Our findings indicate that in the absence of human interventions such as fire suppression, and with increased wildfire frequency, the globally important boreal CH4 sink could be diminished