11,432 research outputs found
Improving water productivity: how do we get more crop from every drop
Water management / Productivity / Irrigation management / Supplemental irrigation / Crop production
Variational Study of Weakly Coupled Triply Heavy Baryons
Baryons made of three heavy quarks become weakly coupled, when all the quarks
are sufficiently heavy such that the typical momentum transfer is much larger
than Lambda_QCD. We use variational method to estimate masses of the
lowest-lying bcc, ccc, bbb and bbc states by assuming they are Coulomb bound
states. Our predictions for these states are systematically lower than those
made long ago by Bjorken.Comment: 31 pages, 5 figure
No-scale D=5 supergravity from Scherk-Schwarz reduction of D=6 theories
We perform a generalized dimensional reduction of six dimensional
supergravity theories to five dimensions. We consider the minimal and
the maximal theories. In each case the reduction allows us to obtain
gauged supergravities of no-scale type in dimension five with gauge groups that
escape previous classifications. In the minimal case, the geometric data of the
reduced theory correspond to particular cases of the D=5 real special geometry.
In the maximal case we find a four parameter solution which allows partial
breaking of supersymmetry.Comment: AMS-LaTeX 16 pages. A reference added, some minor changes performe
Quantum Revivals in a Periodically Driven Gravitational Cavity
Quantum revivals are investigated for the dynamics of an atom in a driven
gravitational cavity. It is demonstrated that the external driving field
influences the revival time significantly. Analytical expressions are presented
which are based on second order perturbation theory and semiclassical secular
theory. These analytical results explain the dependence of the revival time on
the characteristic parameters of the problem quantitatively in a simple way.
They are in excellent agreement with numerical results
Analog of Magnetoelectric Effect in High-Tc Granular Superconductors
We propose the existence of an electric-field induced nonlinear magnetization
in a weakly coupled granular superconductor due to time-parity violation. As
the field increases the induced magnetization passes from para- to dia-magnetic
behavior. We discuss conditions under which this effect could be experimentally
measured in high-temperature superconductors.Comment: REVTEX (epsf style), 1 PS figure; to appear in Europhysics Letter
Adaptation of international guidelines on assessment and management of cancer pain for the Australian context
Aim: To develop clinical practice guidelines for screening, assessing and managing cancer pain in Australian adults.
Methods: This three phase project utilised the ADAPTE approach to adapt international cancer pain guidelines for the Australian setting. A Working Party was established to define scope, screen guidelines for adaptation, and develop recommendations to support better cancer pain control through screening, assessment, pharmacological and non-pharmacological management, and patient education. Recommendations with limited evidence were referred to Expert Panels for advice before the draft guidelines were opened for public consultation via the Cancer Council Australia Cancer Guidelines Wiki platform in late 2012. All comments were reviewed by the Working Party and the guidelines revised accordingly.
Results: Screening resulted in six international guidelines being included for adaptation - those developed by the Scottish Intercollegiate Guidelines Network (2008), National Health Service Quality Improvement Scotland (2009), National Comprehensive Cancer Network (2012), European Society of Medical Oncology (2011), European Association for Palliative Care (2011, 2012) and National Institute of Clinical Excellence (2012). Guideline adaptation resulted in 55 final recommendations. The guidelines were officially launched in November 2013.
Conclusion: International guidelines can be efficiently reconfigured for local contexts using the ADAPTE approach. Availability of the guidelines via the Cancer Council Australia Wiki is intended to promote uptake and enable recommendations to be kept up to date. Resources to support implementation will also be made available via the Wiki if found to be effective by a randomised controlled trial commencing in 2015
Valuing improvements in the water rights system in South Africa : a contingent ranking approach
In the context of increasing water scarcity, understanding is growing that irrigation water rights are important and that a lack of effective water rights systems constitute a major reason for inefficient water management. This study carried out a contingent ranking experiment to study how smallholder irrigators in South Africa would value potential changes in water rights. Three specific dimensions of water rights, relevant for the South African case, are considered: duration, quality of title and transferability. Results indicate that smallholder irrigators are prepared to pay considerably higher water prices if improvements are made in the water rights system. This implies that the proposed interventions in the water rights system would improve the efficiency and productivity of the small-scale irrigation sector. The increased willingness to pay could furthermore also assist South African government to reach the objective of increased cost recovery
Direct mode summation for the Casimir energy of a solid ball
The Casimir energy of a solid ball placed in an infinite medium is calculated
by a direct frequency summation using the contour integration. It is assumed
that the permittivity and permeability of the ball and medium satisfy the
condition . Upon deriving the general
expression for the Casimir energy, a dilute compact ball is considered
. In this case the
calculations are carried out which are of the first order in and take
account of the five terms in the Debye expansion of the Bessel functions
involved. The implication of the obtained results to the attempts of explaining
the sonoluminescence via the Casimir effect is shortly discussed.Comment: REVTeX, 7 pages, no figures and tables, treatment of a dilute
dielectric ball is revised, new references are adde
Matched‐pair and propensity score comparisons of outcomes of patients with clinical stage I non–small cell lung cancer treated with resection or stereotactic radiosurgery
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/98996/1/cncr28100.pd
Spatial aspects of oncogenic signalling determine the response to combination therapy in slice explants from Kras-driven lung tumours
A key question in precision medicine is how functional heterogeneity in solid tumours informs therapeutic sensitivity. We demonstrate that spatial characteristics of oncogenic signalling and therapy response can be modelled in precision-cut slices from Kras-driven non-small-cell lung cancer with varying histopathologies. Unexpectedly, profiling of in situ tumours demonstrated that signalling stratifies mostly according to histopathology, showing enhanced AKT and SRC activity in adenosquamous carcinoma, and mitogen-activated protein kinase (MAPK) activity in adenocarcinoma. In addition, high intertumour and intratumour variability was detected, particularly of MAPK and mammalian target of rapamycin (mTOR) complex 1 activity. Using short-term treatment of slice explants, we showed that cytotoxic responses to combination MAPK and phosphoinositide 3-kinase-mTOR inhibition correlate with the spatially defined activities of both pathways. Thus, whereas genetic drivers determine histopathology spectra, histopathology-associated and spatially variable signalling activities determine drug sensitivity. Our study is in support of spatial aspects of signalling heterogeneity being considered in clinical diagnostic settings, particularly to guide the selection of drug combinations
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