Stability of ESCRT III Snf7 Polymer Influenced by: Bro1 and Vps2/Vps24

The endosomal sorting complexes required for transport (ESCRT) are protein complexes that remodel cellular membranes. The ESCRT III membrane machinery has been implicated in regulating membrane bound receptor proteins through the multi-vesicular body (MVB) pathway, during the end of cytokinesis, and being manipulated by the HIV virus during infection. My thesis project focuses on the in vivo regulation of ESCRT III. Bro1 binding to the Snf7 protein polymer helped stabilize ESCRT III. With this understanding that Bro 1 stabilizes the Snf7 polymer, two questions can be posed: Does it block Vps4 mediated Snf7 disassembly? Or does it block Vps2 and Vps24 from capping the Snf7 polymer? The latter of these two questions is the focus of my thesis. My research has shown the interaction of the capping Vps2:Vps24 dimer to only slightly affect protein sorting in the ESCRT pathway

Imagining the Scandal of the Cross with Graphic/Novel Reading

For countless adherents to the Christian tradition, the Cross functions as a symbol of divine power. For the earliest Christians, however, this overwhelmingly positive valuation of crosses would have been unintelligible. Living under Roman rule, their immediate understanding of crosses would have been as instruments of execution and thus symbols of the power and victory belonging to a foreign empire rather than to the Lord they worshipped. For them, the crucifixion was a traumatic event in which the Messiah died shamefully. It is for these reasons that the scandal of the Cross is a prominent theme in the New Testament, yet it is precisely this scandal that the traditional valuation of the Cross has come to domesticate and exclude from popular interpretation. The academic discipline of biblical interpretation can help readers recapture an understanding and appreciation for this scandal by embracing hermeneutical practices that recognize the weirdness of the Cross. It is weird in that it is a symbol in which the world and the divine come together in startling, confounding, and undeniably violent fashion. The standard practices of biblical interpreters will not do, however, insofar as they remain imbued with modernity\u27s categorical mistrust of the supernatural elements of biblical texts. Comic books and graphic novels, on the other hand, are a contemporary medium in which the most challenging and outlandish elements associated with the Cross are not only tolerated but embraced and appropriated. This dissertation places several New Testament passages that interpret the Cross from Galatians, 1 Corinthians, and Mark\u27s Gospel into dialogue with comics and graphic novel portrayals of the life and death of Jesus. The outcome of this dialogical reading is that the effectiveness in which the comics texts present the weirdness and scandal of the Cross helps illuminate where these same elements are operative in the New Testament. Foremost among the theological implications of this study is the manner in which such an understanding of the Cross increases the power of biblical texts for present-day readers

Prevention of Child Maltreatment in U.S. Air Force Families

The Department of Defense created the Family Advocacy Program (FAP) to provide primary and secondary intervention and prevention services to military families to decrease the risks of family maltreatment. This review synthesized literature to reveal how deployment, domestic abuse, mental health, and substance abuse relate to adult and child maltreatment in the armed forces. Systematic review procedures are used to evaluate nine studies meeting inclusion criteria to correlate factors significant in the increased risk of child maltreatment. Based on results, this paper discusses how FAP can effectively provide primary and secondary services by transitioning from a traditional medical model to a public health model using a social-ecological framework. Additionally, this paper suggests a development of a logic model for FAP by reviewing the already suggested logic model that is more risk focused by including intrapersonal vulnerabilities and assets as well as contextual risks and assets. This paper presents strategies to decrease child maltreatment by identifying the risks, intervening efficiently, and providing adequate primary and secondary services as soon as risks are present compared to once abuse is completed

Book Review of \u3ci\u3eContesting Knowledge: Museums and Indigenous Perspectives \u3c/i\u3e edited by Susan Sleeper-Smith.

Seventeen scholars contributed to this group work. First exposed to compilation books in the eighties, I found the format exhilarating then. There were so many angles, so much information. Now, however, such books are, to me, rather like walking a cobblestone path. Maybe I just have inappropriate shoes, but the journey is seldom entirely smooth going. And having to adapt to different writing styles every 20 to 30 pages is an added hindrance. Still, the genre is here to stay, and Contesting Knowledge has much to recommend it. Analyzed in four out of twelve pieces, the National Museum of the American Indian (NMAI) is viewed from interesting perspectives, and those writings are among the most interesting chapters, along with pieces about particular Native community museums

Present Emphases in Christian Education

Because of the enormity of the field [Christian education] and in order to be very specific the subject matter will be confined to the curricula of the Sunday Church Schools. More specifically, the aim is to examine the present-day emphases that are to be found in the curricula of Christian education and to offer suggestions for the blending of these emphases that will add to the force and effectiveness of the great job already being done in this area of Christian education

Master of Science

thesisThe Durst Mountain-Huntsville area is located about 35 miles northeast of Salt Lake City, Utah, and comprises nearly 110 square miles between Ogden and Weber Valleys. The formations exposed are the Precambrian Farmington Canyon complex; the Cambrian Tintic quartzite, Ophir shale, and Cambrian limestones and dolomites undifferentiated; Devonian Three Forks (?) formation; Mississippian Madison limestone and the Brazer formation; the Triassic Thaynes limestone; and the Tertiary Knight conglomerate, Norwood tuff, and Huntsville fanglomerate. Three episodes of faulting were noted within the area. The Durst thrust is related to mid-Laramide activity. An east-west episode of normal faulting occurred during the Miocene (?). North-south normal faulting occurred during the Pliocene and Pleistocene. The Herd Mountain erosion surface is the oldest erosion surface within the north-central Wasatch Mountains. It is dated as late Oligocene or Miocene age. A more recent erosion surface is the Weber Valley surface. The formation of this occurred in Pliocene or Pleistocene time. An arm of Lake Bonneville extended into both Ogden Valley and Weber Valley

Written Composition in the Intermediate Grades

The problem with which this study is concerned is the development of a program for teaching composition skills to children in the intermediate grades. The study is based on a survey of research, reports, books, and articles in the field, and on the teaching experience of the author. The organization of the study follows the actual steps in initiating a program for composition teaching in the intermediate grades