Plaque Rupture in Coronary Atherosclerosis Is Associated With Increased Plaque Structural Stress.

OBJECTIVES: The aim of this study was to identify the determinants of plaque structural stress (PSS) and the relationship between PSS and plaques with rupture. BACKGROUND: Plaque rupture is the most common cause of myocardial infarction, occurring particularly in higher risk lesions such as fibroatheromas. However, prospective intravascular ultrasound-virtual histology studies indicate that 135 kPa was a good predictor of rupture in higher risk regions. CONCLUSIONS: PSS is determined by plaque composition, plaque architecture, and lumen geometry. PSS and PSS variability are increased in plaques with rupture, particularly at proximal segments. Incorporating PSS into plaque assessment may improve identification of rupture-prone plaques.This work was supported by British Heart Foundation grants CH/20000003/12800, FS/13/33/30168, and FS/15/26/31441; Heart Research UK grant RG2638/14/16 and MRC Confidence in Concepts award; and the NIHR Cambridge Biomedical Research Centre

Domestic Relations - Gifts in Contemplation of Marriage

The Supreme Court of New York held that a donor could not recover an engagement ring upon donee\u27s renouncing her intention to marry him, where the contract to marry was void since the donor was already married. Lowe v. Quinn, 301 N.Y.S.2d 361 (Ist Dep\u27t 1969)

Persuasion in the Courtroom

Persuasion is defined as an act of influencing the minds of others by arguments or reasons, by appeals to both feeling and intellect; it is the art of leading another man\u27s will to a particular choice, or course of conduct. No one doubts this is what trial lawyers do every day in the courtroom-and that is what this article is about

Identification of local and allochthonous flint artefacts from the Middle Paleolithic site Abrigo de la Quebrada (Chelva, Valencia, Spain) by macroscopic and physicochemical methods

Flint is a lithic material that can be worked to obtain sharp blades with conchoidal fractures characteristic of lithic tools as scrapers, hand axes and arrowheads. These artefacts represent the majority of the lithic material from the Palaeolithic sites worldwide, and it continued to be used during subsequent periods to manufacture some of the earliest tools used by man. One of the questions that archaeologists are keen to answer in relation to flint use and characterization is sourcing. Answering this question is important to reconstruct interaction networks of prehistoric cultures. Over the past years, a great variety of analytical methods have been applied to identify the sources of flint artefacts found in different archaeological contexts.[18] The objective of these studies is to determine the chemical composition of geological and archaeological flint samples and to obtain element correspondences to establish the probable geological source of origin for archaeological artefacts