Attitudes of Undergraduate Social Work Students Toward Interprofessional Health Care Practice and Interprofessional Health Care Education

In 2005, the Centre for Collaborative Health Professional Education at Memorial University in Canada commenced an inquiry into the interprofessional education (IPE) of social work students. In the 2005/2006 academic year, undergraduate social work students were introduced to an IPE program at Memorial University for the first time. This interdisciplinary initiative brought together students from pharmacy, nursing, medicine, and social work to develop and encourage interprofessional educational activities with the purpose of increasing collaborative patient-centered practice competencies of students and professionals (Sharpe & Curran, 2006). In the subsequent three academic years (2005/2006, 2006/2007, 2007/2008) Bachelor of Social Work (BSW) students explored a variety of IPE modules. This paper summarizes the available literature on the topic of IPE and reports on data collected from three cohorts of undergraduate social work students regarding their attitudes toward interdisciplinary team practice. Data collected are in relation to the Health and Wellbeing of Children module, one of the five module topics in which these students participated over the three-year period. It is proposed that by understanding student attitudes as they are evidenced at this early stage of professional development, valuable information will be provided to educators to inform best practices in the teaching and learning of interprofessional practice skills within the discipline of social work. Finally, the authors provide suggested directions for future research

Patient population with multiple myeloma and transitions across different lines of therapy in the USA: an epidemiologic model.

PURPOSE: Multiple myeloma (MM) is a progressive, malignant neoplasia with a worldwide, age-standardized annual incidence of 1.5 per 100 000 individuals and 5-year prevalence around 230 000 patients. Main favorable prognostic factors are younger age, low/standard cytogenetic risk, and undergoing stem cell transplantation. Our aim was to estimate the size of the patient population with MM eligible to receive a new MM therapy at different lines of therapy in the USA. METHODS: We constructed a compartmental, differential equation model representing the flow of MM patients from diagnosis to death, via two possible treatment pathways and distinguished in four groups based on prognostic factors. Parameters were obtained from published references, available statistics, and assumptions. The model was used to estimate number of diagnosed MM patients and number of patient transitions from one line of therapy to the next over 1 year. Model output included 95% credible intervals from probabilistic sensitivity analyses. RESULTS: The base-case estimates were 80 219 patients living with MM, including 70 375 on treatment, 780 symptomatic untreated patients, and 9064 asymptomatic untreated patients. Over a 1-year period, the number of MM patients on treatment line 1 was estimated at 23 629 (credible intervals 22 236-25 029), and the number of transitions from treatment line 1 to treatment line 2 was estimated at 14 423. CONCLUSIONS: The size of the patient population with MM on different lines of therapy and in patient subgroups of interest estimated from this epidemiologic model can be used to assess the number of patients who could benefit from new MM therapies and their corresponding budgetary impact. Copyright © 2016 John Wiley & Sons, Ltd

The impact of ‘child removal’ in nineteenth and early twentieth century Britain : A life course approach

Forum Modernisation, Women and Children : ‘child removal’ in Britain and beyond : a lifecourse approac

A Review of the Effects of Different Types of Stigmas on the Retention Rates of Patients in Medication-Assisted Treatment and How to Combat the Problem

It is difficult to turn on the news without hearing about the opioid epidemic or a recent opioid overdose. There is hope because there is a treatment to help prevent this epidemic. That treatment is known as medication-assisted therapy (MAT), where patients can present and, if they meet the criteria, can be given a prescription for buprenorphine/naloxone combination medication. Treatment with buprenorphine/naloxone has been shown to be highly effective treatment for substance use disorder (SUD). Even though it has been proven that this combination works, less than 20% of patients diagnosed with SUD present for treatment. This study focused on how patients diagnosed with SUD attending a MAT program perceive internalized stigma before and after an educational program on self-stigma. A combination of pre- and post-questionnaires and an educational program on combating self-stigma were presented. The results of the pre-test survey indicated that overall, internalized stigma was moderate, with a mean average of 2.41%. The post-survey results indicated that those surveyed remained in the moderate category with a mean average of 2.09%. This indicated that the educational program influenced the lowering of self-stigma but did not significantly lower scores, meaning more work is needed. If we are to combat the opioid crisis, practitioners must be aware and understand that patient\u27s self-stigma has real-world effects which could lead to relapse, overdose, and possibly death

Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS)

Background: Amyotrophic lateral sclerosis (ALS), a common late-onset neurodegenerative disease, is associated with fronto-temporal dementia (FTD) in 3-10% of patients. A mutation in CHMP2B was recently identified in a Danish pedigree with autosomal dominant FTD. Subsequently, two unrelated patients with familial ALS, one of whom also showed features of FTD, were shown to carry missense mutations in CHMP2B. The initial aim of this study was to determine whether mutations in CHMP2B contribute more broadly to ALS pathogenesis. Methodology/Principal Findings: Sequencing of CHMP2B in 433 ALS cases from the North of England identified 4 cases carrying 3 missense mutations, including one novel mutation, p. Thr104Asn, none of which were present in 500 neurologically normal controls. Analysis of clinical and neuropathological data of these 4 cases showed a phenotype consistent with the lower motor neuron predominant (progressive muscular atrophy (PMA)) variant of ALS. Only one had a recognised family history of ALS and none had clinically apparent dementia. Microarray analysis of motor neurons from CHMP2B cases, compared to controls, showed a distinct gene expression signature with significant differential expression predicting disassembly of cell structure; increased calcium concentration in the ER lumen; decrease in the availability of ATP; down-regulation of the classical and p38 MAPK signalling pathways, reduction in autophagy initiation and a global repression of translation. Transfection of mutant CHMP2B into HEK-293 and COS-7 cells resulted in the formation of large cytoplasmic vacuoles, aberrant lysosomal localisation demonstrated by CD63 staining and impairment of autophagy indicated by increased levels of LC3-II protein. These changes were absent in control cells transfected with wild-type CHMP2B. Conclusions/Significance: We conclude that in a population drawn from North of England pathogenic CHMP2B mutations are found in approximately 1% of cases of ALS and 10% of those with lower motor neuron predominant ALS. We provide a body of evidence indicating the likely pathogenicity of the reported gene alterations. However, absolute confirmation of pathogenicity requires further evidence, including documentation of familial transmission in ALS pedigrees which might be most fruitfully explored in cases with a LMN predominant phenotype

Improving Community Advisory Board Engagement In Precision Medicine Research To Reduce Health Disparities

Community Advisory Boards (CABs) are used in efforts to reduce health disparities; however, there is little documentation in the literature regarding their use in precision medicine research. In this case study, an academic-CAB partnership developed a questionnaire and patient educational materials for two precision smoking cessation interventions that involved use of genetic information. The community-engaged research (CEnR) literature provided a framework for enhancing benefits to CAB members involved in developing research documents for use with a low-income, ethnically diverse population of smokers. The academic partners integrated three CEnR strategies: 1) in-meeting statements acknowledging their desire to learn from community partners, 2) in-meeting written feedback to and from community partners, and 3) a survey to obtain CAB member feedback post-meetings. Strategies 1 and 2 yielded modifications to pertinent study materials, as well as suggestions for improving meeting operations that were then adopted, as appropriate, by the academic partners. The survey indicated that CAB members valued the meeting procedure changes which appeared to have contributed to improvements in attendance and satisfaction with the meetings. Further operationalization of relevant partnership constructs and development of tools for measuring these aspects of community-academic partnerships is warranted to support community engagement in precision medicine research studies

Clarifying the Need for Inpatient Medication Education

Low health literacy is a problem for millions of Americans resulting in increased use of avoidable healthcare resources and poor health outcomes. Use of pharmaceutical regimens to manage acute and chronic health issues is the most common treatment modality. Unfortunately, people with low health literacy may have trouble understanding and following provider instructions; reading and following directions on medication bottles, either prescribed and/or over the counter; and identifying proper reasons for taking a medication. The purpose of this study was to increase patient self-agency for the treatment and management of acute and chronic health conditions through medication education. Providing medication education to the hospitalized patient may result in increased knowledge and self-management ability. Secondary rewards involve the increase in hospital reimbursement through increased patient satisfaction scores

Ecological Conditions of the Papillion Creek Watershed: Effects of Adjacent Land-Use.

Stream conditions were assessed for past and present landscapes of the Papillion Creek Watershed of northwest Omaha, Nebraska based on historical records, present land-use surveys and field data collected in June 2000 using the Environmental Protection Agency’s Rapid Bioassessment Protocol modified to meet the needs of the study. Less than 0.4% of the historic tallgrass Prairie remains, with the present landscape mostly in agriculture (83%) or residential-commercial developments (16%). No significant differences (P ≤ 0.05) were found between ten habitat parameters measured for each of three land-used categories, cultivated, residential-commercial, and other. The overall impact of increased land-use on the Papillion Creek was reflected in marginal conditions (1 = poor; 20 = optimal) for all ten habitat parameters evaluated although not all work equally as effected: Epifaunal Substrate/Available Cover (mean score = 8.3), Pool Substrate Characterization (mean score = 8.8), Pool Variability (mean score = 7.0), Sediment Deposition (mean score = 9.0), Channel Flow (mean score = 10.8), Channel Alteration (mean score = 8.3), Channel Sinuosity (mean score = 6.8), Bank Stability (mean score = 5.2), Vegetative Protection (mean score = 6.2), and Riparian Vegetative Zone Width (mean score = 3.4). Compared to the degree of channel alteration, Channel Sinuosity was the habitat parameter most significantly affected (P ≤ 0.000+). In combination, these results quantify the impact of urban expansion on stream ecosystems and support arguments for minimizing development along waterways in order to maintain the ecosystem services and habitat diversity that they provide to urban areas