6,523 research outputs found
Effects of Rotationally-Induced Mixing in Compact Binary Systems with Low-Mass Secondaries and in Single Solar-Type Stars
Many population synthesis and stellar evolution studies have addressed the
evolution of close binary systems in which the primary is a compact remnant and
the secondary is filling its Roche lobe, thus triggering mass transfer.
Although tidal locking is expected in such systems, most studies have neglected
the rotationally-induced mixing that may occur. Here we study the possible
effects of mixing in the mass-losing stars for a range in secondary star masses
and metallicities. We find that tidal locking can induce rotational mixing
prior to contact and thus affect the evolution of the secondary star if the
effects of the Spruit-Tayler dynamo are included both for angular momentum and
chemical transport. Once contact is made, the effect of mass transfer tends to
be more rapid than the evolutionary time scale, so the effects of mixing are no
longer directly important, but the mass transfer strips matter to inner layers
that may have been affected by the mixing. These effects are enhanced for
secondaries of 1-1.2 Msun and for lower metallicities. We discuss the possible
implications for the paucity of carbon in the secondaries of the cataclysmic
variable SS Cyg and the black hole candidate XTE J1118+480 and for the
progenitor evolution of Type Ia supernovae. We also address the issue of the
origin of blue straggler stars in globular and open clusters. We find that for
models that include rotation consistent with that observed for some blue
straggler stars, evolution is chemically homogeneous. This leads to tracks in
the HR diagram that are brighter and bluer than the non-rotating main-sequence
turn-off point. Rotational mixing could thus be one of the factors that
contribute to the formation of blue stragglers.Comment: 46 pages, 18 figure
Containerless low gravity processing of glass forming and immiscible alloys
Under normal one-g conditions immiscible alloys segregate extensively during solidification due to sedimentation of the more dense of the immiscible liquid phases. Immiscible (hypermonotectic) gold-rhodium alloys were processed in the 100 meter drop tube under low gravity, containerless conditions to determine the feasibility of producing dispersed structures. Three alloy compositions were utilized. Alloys containing 10 percent by volume of the gold-rich hypermonotectic phase exhibited a tendency for the gold-rich liquid to wet the outer surface of the samples. This wetting tendency led to extensive segregation in several cases. Alloys containing 80 and 90 percent by volume of the gold-rich phase possessed completely different microstructures from the 10 percent samples when processed under low-g, containerless conditions. Several samples exhibited microstructures consisting of well dispersed 2 to 3 microns diameter rhodium-rich spheres in a gold-rich matrix
Overview of Environmental Durability Coatings and Test Capabilities
Overview of LME organizations capabilities including the Analytical and experimental capabilities of the Environmental Effects and Coatings Branch (LME), Case Studies - Past Hypersonics related work, and current capabilities relevant for future hypersonic work with multi-layer coatings concepts and unique testing capabilities
The short-term impact of the alcohol act on alcohol-related deaths and hospital admissions in Scotland: a natural experiment
Background and aim:
The introduction of the Alcohol Act in Scotland on 1 October 2011, which included a ban on multi-buy promotions, was likely associated with a fall in off-trade alcohol sales in the year after its implementation. The aim of this study was to test if the same legislation was associated with reduced levels of alcohol-related deaths and hospital admissions in the 3-year period after its introduction.
Design:
A natural experiment design using time series data to assess the impact of the Alcohol Act legislation in Scotland. Comparisons were made with unexposed populations in the rest of Great Britain.
Setting
Scotland with comparable data obtained for geographical control groups in other parts of Great Britain.
Participants:
For alcohol-related deaths, a total of 17,732 in Scotland and 88,001 in England/Wales across 169 four-week periods between January 2001 and December 2013. For alcohol-related hospital admissions, a total of 121,314 in Scotland and 696,892 in England across 182 four-week periods between January 2001 and December 2014.
Measurements:
Deaths and hospital admissions in Scotland and control groups that were wholly attributable to alcohol for consecutive four-week periods between January 2001 and December 2014. Data were obtained by age, sex and area-based socioeconomic position.
Findings:
There was no evidence to suggest that the Alcohol Act was associated with changes in the overall rate of alcohol-related deaths [incidence rate ratio (IRR) 0.99, 95% confidence interval (0.91 to 1.07)] or hospital admissions [IRR 0.98 (0.95 to 1.02)] in Scotland. In control group analyses, the pseudo intervention variable was not associated with a change in alcohol-related death rates in England/Wales [IRR 0.99 (0.95 to 1.02)], but was associated with an increase in alcohol-related hospital admission rates in England [IRR 1.05 (1.03 to 1.07)]. In combined models, the interaction analysis did not provide support for a ‘net effect’ of the legislation on alcohol-related deaths in Scotland compared with England/Wales [IRR 0.99 (0.95 to 1.04)], but suggested a net reduction in hospital admissions for Scotland compared with England [IRR 0.93 (0.87 to 0.98)].
Conclusion:
The implementation of the Alcohol Act in Scotland has not been associated clearly with a reduction in alcohol-related deaths or hospital admissions in the 3-year period after it was implemented in October 2011
Testing and Characterization of CMC Combustor Liners
Multiple combustor liner applications, both segmented and fully annular designs, have been configured for exposure in NASA's High Pressure Burner Rig (HPBR). The segmented liners were attached to the rig structure with SiC/SiC fasteners and exposed to simulated gas turbine conditions for nearly 200 hours. Test conditions included pressures of 6 atm., gas velocity of 42 m/s, and gas temperatures near 1450 C. The temperatures of both the cooled and combustion flow sides of the liners were measured using optical and contact measurement techniques. Minor weight loss was observed, but the liners remained structural sound, although damage was noted in some fasteners
Synthetic control methodology as a tool for evaluating population-level health interventions
Background: Many public health interventions cannot be evaluated using randomised controlled trials so they rely on the assessment of observational data. Techniques for evaluating public health interventions using observational data include interrupted time series analysis, panel data regression-based approaches, regression discontinuity and instrumental variable approaches. The inclusion of a counterfactual improves causal inference for approaches based on time series analysis, but the selection of a suitable counterfactual or control area can be problematic. The synthetic control method builds a counterfactual using a weighted combination of potential control units.
Methods: We explain the synthetic control method, summarise its use in health research to date, set out its advantages, assumptions and limitations and describe its implementation through a case study of life expectancy following German reunification.
Results: Advantages of the synthetic control method are that it offers an approach suitable when there is a small number of treated units and control units and it does not rely on parallel preimplementation trends like difference in difference methods. The credibility of the result relies on achieving a good preimplementation fit for the outcome of interest between treated unit and synthetic control. If a good preimplementation fit is established over an extended period of time, a discrepancy in the outcome variable following the intervention can be interpreted as an intervention effect. It is critical that the synthetic control is built from a pool of potential controls that are similar to the treated unit. There is currently no consensus on what constitutes a ‘good fit’ or how to judge similarity. Traditional statistical inference is not appropriate with this approach, although alternatives are available. From our review, we noted that the synthetic control method has been underused in public health.
Conclusions: Synthetic control methods are a valuable addition to the range of approaches for evaluating public health interventions when randomisation is impractical. They deserve to be more widely applied, ideally in combination with other methods so that the dependence of findings on particular assumptions can be assessed
Upper Temperature Limit of Environmental Barrier Coatings for Enabling Propulsion Materials Established
Silicon-based ceramics, such as SiC/SiC composites and Si3N4, are the prime candidates for hot section structural components of next-generation gas turbines. A key barrier to such an application is the rapid recession of silicon-based ceramics in combustion environments because of the volatilization of silica scale by water vapor (refs. 1 and 2). Environmental barrier coatings (EBC's) were developed to prevent recession in the High Speed Research--Enabling Propulsion Materials (HSR-EPM) Program (refs. 3 and 4). An investigation under the Ultra-Efficient Engine Technology Program was undertaken at the NASA Glenn Research Center to establish the upper temperature limit of the EPM EBC
Treatment utilization and outcomes in elderly patients with locally advanced esophageal carcinoma: A review of the National Cancer Database
For elderly patients with locally advanced esophageal cancer, therapeutic approaches and outcomes in a modern cohort are not well characterized. Patients ≥70 years old with clinical stage II and III esophageal cancer diagnosed between 1998 and 2012 were identified from the National Cancer Database and stratified based on treatment type. Variables associated with treatment utilization were evaluated using logistic regression and survival evaluated using Cox proportional hazards analysis. Propensity matching (1:1) was performed to help account for selection bias. A total of 21,593 patients were identified. Median and maximum ages were 77 and 90, respectively. Treatment included palliative therapy (24.3%), chemoradiation (37.1%), trimodality therapy (10.0%), esophagectomy alone (5.6%), or no therapy (12.9%). Age ≥80 (OR 0.73), female gender (OR 0.81), Charlson-Deyo comorbidity score ≥2 (OR 0.82), and high-volume centers (OR 0.83) were associated with a decreased likelihood of palliative therapy versus no treatment. Age ≥80 (OR 0.79) and Clinical Stage III (OR 0.33) were associated with a decreased likelihood, while adenocarcinoma histology (OR 1.33) and nonacademic cancer centers (OR 3.9), an increased likelihood of esophagectomy alone compared to definitive chemoradiation. Age ≥80 (OR 0.15), female gender (OR 0.80), and non-Caucasian race (OR 0.63) were associated with a decreased likelihood, while adenocarcinoma histology (OR 2.10) and high-volume centers (OR 2.34), an increased likelihood of trimodality therapy compared to definitive chemoradiation. Each treatment type demonstrated improved survival compared to no therapy: palliative treatment (HR 0.49) to trimodality therapy (HR 0.25) with significance between all groups. Any therapy, including palliative care, was associated with improved survival; however, subsets of elderly patients with locally advanced esophageal cancer are less likely to receive aggressive therapy. Care should be taken to not unnecessarily deprive these individuals of treatment that may improve survival
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