2,021 research outputs found
Space station Platform Management System (PMS) replanning using resource envelopes
One of the responsibilities of the Space Station Platform Management System (PMS) is to maintain constraint-free, short-term plans for platform and free-flyer activities. Both the replanning function and the associated constraint-checking function are viewed as potentially requiring expert system assistance. The PMS Resource Envelope Scheduling System (PRESS) expert system, which is currently under development, is described. The PRESS capabilities will include the following: plan, replan, and perform constraint checking using resource envelopes resembling those required for telescience; initialize itself using the results fo a previous run; infer the replanning needs associated with a change in resource availability; allow the user to determine the level of interaction (including an advisory capability) with the system during execution; and generate both a graphic timeline and a report as output. The PRESS is being developed on an IBM PC/AT using TeKnowledge, Inc.'s M.1 expert system shell. The PRESS activity definitions and constraints are based on those defined for the Cosmic Background Explorer (COBE) mission scheduled for launch in early 1989
Integrated Logistics Product Support for the 21st Century Program
Logistics Engineering and Analysis. Over 144 years of combined experience via backgrounds in commerical industry logistics
Predominance of weakly cytotoxic, T-betLowEomesNeg CD8+ T-cells in human gastrointestinal mucosa: implications for HIV infection.
The gastrointestinal mucosa is an important site of HIV acquisition, viral replication, and pathogenesis. Immune cells in mucosal tissues frequently differ in phenotype and function from their non-mucosal counterparts. Although perforin-mediated cytotoxicity as measured in blood is a recognized correlate of HIV immune control, its role in gastrointestinal tissues is unknown. We sought to elucidate the cytotoxic features of rectal mucosal CD8+ T-cells in HIV infected and uninfected subjects. Perforin expression and lytic capacity were significantly reduced in rectal CD8+ T-cells compared with their blood counterparts, regardless of HIV clinical status; granzyme B (GrzB) was reduced to a lesser extent. Mucosal perforin and GrzB expression were higher in participants not on antiretroviral therapy compared with those on therapy and controls. Reduction in perforin and GrzB was not explained by differences in memory/effector subsets. Expression of T-bet and Eomesodermin was significantly lower in gut CD8+ T-cells compared with blood, and in vitro neutralization of TGF-β partially restored perforin expression in gut CD8+ T-cells. These findings suggest that rectal CD8+ T-cells are primarily non-cytotoxic, and phenotypically shaped by the tissue microenvironment. Further elucidation of rectal immune responses to HIV will inform the development of vaccines and immunotherapies targeted to mucosal tissues
Depression, Relationship Quality, and Couples’ Demand/Withdraw and Demand/Submit Sequential Interactions
This study investigated the associations among depression, relationship quality, and demand/withdraw and demand/submit behavior in couples’ conflict interactions. Two 10-min conflict interactions were coded for each couple (N = 97) using Structural Analysis of Social Behavior (SASB; Benjamin, 1979a, 1987, 2000a). Depression was assessed categorically (via the presence of depressive disorders) and dimensionally (via symptom reports). Results revealed that relationship quality was negatively associated with demanding behavior, as well as receiving submissive or withdrawing behavior from one’s partner. Relationship quality was positively associated with withdrawal. Demanding behavior was positively associated with women’s depression symptoms but negatively associated with men’s depression symptoms. Sequential analysis revealed couples’ behavior was highly stable across time. Initiation of demand/withdraw and demand/submit sequences were negatively associated with partners’ relationship adjustment. Female demand/male withdraw was positively associated with men’s depression diagnosis. Results underscore the importance of sequential analysis when investigating associations among depression, relationship quality, and couples’ interpersonal behavior
Systematic Theoretical Search for Dibaryons in a Relativistic Model
A relativistic quark potential model is used to do a systematic search for
quasi-stable dibaryon states in the , , and three flavor world.
Flavor symmetry breaking and channel coupling effects are included and an
adiabatic method and fractional parentage expansion technique are used in the
calculations. The relativistic model predicts dibaryon candidates completely
consistent with the nonrelativistic model.Comment: 12 pages, latex, no figure
Capillary zone electrophoretic studies of ion association between inorganic anions and tetraalkylammonium ions in aqueous-dioxane media
Ion association between inorganic anions and symmetrical tetraalkylammonium ions, R4N+ (R = Me, Et, Pr, n-Bu, n-Am, and 2-methyl butyl {isoamyl = iAm}) was investigated using ordinary silica capillary by capillary zone electrophoresis. An improved version of the Williams-Vigh method was used for the first time to measure the mobilities of the inorganic anions. Plots of log K-ass against log dielectric constant in various media, revealed a smaller change in K-ass compared to dielectric constant. These plots suggest that the Bjerrum's equation is inadequate in accounting for the associations of ions in a CZE setup. </p
Early phenology and growth trait variation in closely related European pine species
Closely related taxa occupying different environments are valuable systems for studying evolution. In this study, we examined differences in early phenology (bud set, bud burst) and early growth in a common garden trial of closely related pine species: Pinus sylvestris, P. mugo, and P. uncinata. Seeds for the trial were sourced from populations across the ranges of each species in Europe. Over first 4 years of development, clear differences were observed between species, while the most significant intraspecific differentiation was observed among plants from P. sylvestris populations from continental European locations. Trait differences within P. sylvestris were highly correlated with altitude and latitude of the site of origin. Meanwhile, P. mugo populations from the Carpathians had the earliest bud set and bud flush compared to other populations of the species. Overall, populations from the P. mugo complex from heterogeneous mountain environments and P. sylvestris from the Scottish Highlands showed the highest within-population variation for the focal traits. Although the three species have been shown to be genetically highly similar, this study reveals large differences in key adaptive traits both among and within species
A new approach to perturbation theory for a Dirac particle in a central field
The explicit semiclassical treatment of logarithmic perturbation theory for
the bound-state problem within the framework of the Dirac equation is
developed. Avoiding disadvantages of the standard approach in the description
of exited states, new handy recursion formulae with the same simple form both
for ground and exited states have been obtained. As an example, the
perturbation expansions for the energy eigenvalues for the Yukawa potential
containing the vector part as well as the scalar component are considered.Comment: 12 pages, LaTe
An Extension of the Fractional Parentage Expansion to Nonrelativistic and Relativistic Dibaryon Calculations
The fractional parentage expansion method is extended from
nonrelativistic to and relativistic dibaryon calculations. A
transformation table between physical bases and symmetry bases for the
dibaryon is provided. A program package has been written for
dibaryon calculation based on the fractional parentage expansion method.Comment: 15 pages text plus 18 pages tables, latex, no figure
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