5,492 research outputs found
Developing a draft learning progression framework for ESOL in New Zealand schools
Early in 2003 we were commissioned to produce a draft Learning Progression Framework (LPF) for ESOL in the New Zealand curriculum. The draft Framework was completed in June 2003 and entered the consultation round. In producing the draft Framework, we had to address a range of issues. Some these related to user expectations. Others concerned the relationship between the draft Framework and documents such as English in the New Zealand Curriculum, existing curriculum documents relating to other languages, and ESOL frameworks available in other countries. These issues proved to be critical. This paper explores some of these issues and introduces the draft Framework
Pain in traumatic upper limb amputees in Sierra Leone.
Data on 40 upper limb amputees (11 bilateral) with regard to stump pain, phantom sensation and phantom pain is presented. All the patients lost their limbs as a result of violent injuries intended to terrorise the population and were assessed 10-48 months after the injury. All amputees reported stump pain in the month prior to interview and ten of the 11 bilateral amputees had bilateral pain. Phantom sensation was common (92.5%), but phantom pain was only present in 32.5% of amputees. Problems in translation and explanation may have influenced the low incidence of phantom pain and high incidence of stump pain. In the bilateral amputees phantom sensation, phantom pain and telescoping all showed bilateral concordance, whereas stump pain and neuromas did not show concordance. About half the subjects (56%) had lost their limb at the time of injury (primary) while the remainder had an injury, then a subsequent amputation in hospital (secondary). There was no association between the incidence of phantom pain and amputation irrespective of being primary or secondary
Recommended from our members
Hemidactylus mabouia
Number of Pages: 11Integrative BiologyGeological Science
Isoprene oxidation by the gram-negative model bacterium variovorax sp. WS11
Plant-produced isoprene (2-methyl-1,3-butadiene) represents a significant portion of global volatile organic compound production, equaled only by methane. A metabolic pathway for the degradation of isoprene was first described for the Gram-positive bacterium Rhodococcus sp. AD45, and an alternative model organism has yet to be characterised. Here, we report the characterisation of a novel Gram-negative isoprene-degrading bacterium, Variovorax sp. WS11. Isoprene metabolism in this bacterium involves a plasmid-encoded iso metabolic gene cluster which differs from that found in Rhodococcus sp. AD45 in terms of organisation and regulation. Expression of iso metabolic genes is significantly upregulated by both isoprene and epoxyisoprene. The enzyme responsible for the initial oxidation of isoprene, isoprene monooxygenase, oxidises a wide range of alkene substrates in a manner which is strongly influenced by the presence of alkyl side-chains and differs from other well-characterised soluble diiron monooxygenases according to its response to alkyne inhibitors. This study presents Variovorax sp. WS11 as both a comparative and contrasting model organism for the study of isoprene metabolism in bacteria, aiding our understanding of the conservation of this biochemical pathway across diverse ecological niches
The Lizards of Rarotonga and Mangaia, Cook Island Group, Oceania
Eight species of lizards are reported from the islands of Rarotonga
and Mangaia with comments on their distribution, ecology, reproduction,
and variation. Particular attention is given to systematic problems in the genus
Cryptoblepharus and pattern polymorphism in Emoia cyanura. Emoia trossula,
recently described from Fiji, is reported for the first time in the Cook Islands.
Historic and zoogeographic evidence suggests that most species of lizards arrived
on Rarotonga and Mangaia in Polynesian voyaging canoes within the past 1000
years, although Gehyra mutilata and Hemidactylus garnotii may have arrived by
incidental boat or air transport in the past several decades
Theory of magnetism with temporal disorder applied to magnetically doped ZnO
A dynamic model of the asymmetric Ising glass is presented: an Ising model
with antiferromagnet bonds with probabilities q arranged at random in a
ferromagnetic matrix. The dynamics is introduced by changing the arrangement of
the antiferromagnetic bonds after n Monte Carlo steps but keeping the same
value of q and spin configuration. In the region where there is a second order
transition between the ferromagnetic and paramagnetic states the dynamic
behaviour follows that expected for motional narrowing and reverts to the
static behaviour only for large n. There is a different dynamic behaviour where
there is a first order transition between the ferromagnetic and spin glass
states where it shows no effects of motional narrowing. The implications of
this are discussed. This model is devised to explain the properties of doped
ZnO where the magnetisation is reduced when the exchange interactions change
with time.Comment: Paper was presented at MMM 2008 and is accepted for publication in
J.A.
Social, environmental and psychological factors associated with objective physical activity levels in the over 65s
Objective: To assess physical activity levels objectively using accelerometers in community dwelling over 65 s and to examine associations with health, social, environmental and psychological factors. Design: Cross sectional survey. Setting: 17 general practices in Scotland, United Kingdom. Participants: Random sampling of over 65 s registered with the practices in four strata young-old (65–80 years), old-old (over 80 years), more affluent and less affluent groups. Main Outcome Measures: Accelerometry counts of activity per day. Associations between activity and Theory of Planned Behaviour variables, the physical environment, health, wellbeing and demographic variables were examined with multiple regression analysis and multilevel modelling. Results: 547 older people (mean (SD) age 79(8) years, 54% female) were analysed representing 94% of those surveyed. Accelerometry counts were highest in the affluent younger group, followed by the deprived younger group, with lowest levels in the deprived over 80 s group. Multiple regression analysis showed that lower age, higher perceived behavioural control, the physical function subscale of SF-36, and having someone nearby to turn to were all independently associated with higher physical activity levels (R2 = 0.32). In addition, hours of sunshine were independently significantly associated with greater physical activity in a multilevel model. Conclusions: Other than age and hours of sunlight, the variables identified are modifiable, and provide a strong basis for the future development of novel multidimensional interventions aimed at increasing activity participation in later life.Peer reviewe
Infinite stacking of alternating polyfluoroaryl rings and bromide anions
The crystal structure of 1-(4-bromo-2,3,5,6-tetrafluorophenyl)-3-benzylimidazolium bromide comprises columns of parallel bromotetrafluorophenyl rings with an interplanar distance of 6.936(6) Å separated by bromide anions
Regulation of plasmid-encoded isoprene metabolism in Rhodococcus, a representative of an important link in the global isoprene cycle
Emissions of biogenic volatile organic compounds (VOCs) form an important part of the global carbon cycle, comprising a significant proportion of net ecosystem productivity. They impact atmospheric chemistry and contribute directly and indirectly to greenhouse gases. Isoprene, emitted largely from plants, comprises one third of total VOCs, yet in contrast to methane, which is released in similar quantities, we know little of its biodegradation. Here, we report the genome of an isoprene degrading isolate, Rhodococcus sp. AD45, and, using mutagenesis shows that a plasmid-encoded soluble di-iron centre isoprene monooxygenase (IsoMO) is essential for isoprene metabolism. Using RNA sequencing (RNAseq) to analyse cells exposed to isoprene or epoxyisoprene in a substrate-switch time-course experiment, we show that transcripts from 22 contiguous genes, including those encoding IsoMO, were highly upregulated, becoming among the most abundant in the cell and comprising over 25% of the entire transcriptome. Analysis of gene transcription in the wild type and an IsoMO-disrupted mutant strain showed that epoxyisoprene, or a subsequent product of isoprene metabolism, rather than isoprene itself, was the inducing molecule. We provide a foundation of molecular data for future research on the environmental biological consumption of this important, climate-active compound
- …
