A 4D Light-Field Dataset and CNN Architectures for Material Recognition

We introduce a new light-field dataset of materials, and take advantage of the recent success of deep learning to perform material recognition on the 4D light-field. Our dataset contains 12 material categories, each with 100 images taken with a Lytro Illum, from which we extract about 30,000 patches in total. To the best of our knowledge, this is the first mid-size dataset for light-field images. Our main goal is to investigate whether the additional information in a light-field (such as multiple sub-aperture views and view-dependent reflectance effects) can aid material recognition. Since recognition networks have not been trained on 4D images before, we propose and compare several novel CNN architectures to train on light-field images. In our experiments, the best performing CNN architecture achieves a 7% boost compared with 2D image classification (70% to 77%). These results constitute important baselines that can spur further research in the use of CNNs for light-field applications. Upon publication, our dataset also enables other novel applications of light-fields, including object detection, image segmentation and view interpolation.Comment: European Conference on Computer Vision (ECCV) 201

Понятие внешней среды в современном менеджменте

Анализируются изменения, произошедшие в определении понятия "внешняя среда". Приводятся различные подходы к определению факторов, входящих во внешнюю среду предприятия. В процессе рассмотрения особое внимание уделяется изменениям, происходящим в определении факторов данной среды в современном менеджменте. По результатам исследования определен современный состав факторов внешней среды, определена их роль в становлении концепта "современный менеджмент" в России

Приближенное решение задачи динамики гелеобразования

Рассмотрены уравнения, описывающие движение зонда вибрационного датчика вязкости в гелеобразующей вязкоупругой среде. Описано получение приближенных решений для определения вязкости и сдвиговой упругости, и проведено сравнение с точным решением

Indolyl Phosphine Nickel(II) Fluorido Complexes: Synthesis and Intermediates in Suzuki–Miyaura Cross‐Coupling Reactions

The C−F bond activation of pentafluoropyridine and 2,3,5,6-tetrafluoropyridine at [Ni(cod)2] (cod=1,5-cyclooctadiene) in the presence of the phosphine PPh2(Ind) (Ind=3-methyl-2-indolyl) led to the formation of the nickel(II) fluorido bis(phosphine) complexes trans-[Ni(F)(2-C5NF4){PPh2(Ind)}2] and trans-[Ni(F)(2-C5HNF3){PPh2(Ind)}2]. The complexes are characterized by the presence of intramolecular hydrogen bonds between the NH group of the phosphine ligands and the fluorido ligand. Stochiometric model reactions of nickel(II) fluorido complexes with PhB(OH)2 revealed that the former can be considered as intermediates in Suzuki–Miyaura cross coupling reactions. Catalytic experiments were attempted using 10 mol-% of trans-[Ni(F)(2-C5NF4){PPh2(Ind)}2] as catalyst and the activities of the PPh2(Ind) complex were compared to the ones of an analogous nickel(II) fluorido complex, bearing PPh3 instead of PPh2(Ind) as ligands. The latter exhibited a somewhat lower catalytic activity suggesting a slight influence of the H-bonds in the outer coordination sphere.Deutsche ForschungsgemeinschaftPeer Reviewe

Unele probleme în tratamentul tuberculozei pulmonare multidrogrezistentă.

Monitorizarea în timp util şi intensiv şi eliminarea efectelor adverse ale medicamentelor de linia a doua sunt componente esenţiale ale programelor de control a DR-TB. Gestionare defectuoasa a pacienților cu efecte secundare creşte riscul întreruperii tratamentului sau tratament neregulat, care poate deveni o cauză de deces sau boală pe termen îndelungat. Stoparea completă a chimioterapiei este necesară numai în cazuri rare. Preparatele medicamentoase auxiliare ameliorează toleranţa chimioterapiei de bază

Новые подходы в лечении лекарственно - устойчивого туберкулеза

Multidrug - resistant (MDR TB) tuberculosis (TB), resistant to isoniazid and rifampicin, continues to be one of the most important threats to controlling the TB epidemic. Over the last few years, there have been promising advances in the paradigm of MDR TB treatment: new drugs have shown activity against Mycobacterium tuberculosis (MBT) and several all - oral short regimens to treat MDR TB have shown promising results. The purpose of this comprehensive review is to summarize the recommended regimens to treat MDR TB, and we also summarize new insights into the treatment of patients with MDR TB.Tuberculoza drogrezistentă (TB MDR), rezistentă la izoniazidă și rifampicină, continuă să fie una dintre cele mai importante amenințări în adresa controlului epidemiei de TB. În ultimii ani, s-au înregistrat progrese promițătoare în paradigma tratamentului TB MDR: noi medicamente și-au demonstrat activitatea împotriva Mycobacterium tuberculosis (MBT) și mai multe regimuri scurte, integral orale pentru tratarea TB MDR au prezentat rezultate promițătoare. Scopul acestei revizuiri cuprinzătoare este de a rezuma regimurile recomandate de OMS pentru tratarea TB MDR și, de asemenea, rezumăm noile perspective privind tratamentul pacienților cu TB MDR.Туберкулез с множественной лекарственной устойчивостью (МЛУ ТБ), резистентный к изониазиду и рифампицину, остается одной из важнейших угроз для контроля эпидемии туберкулеза. За последние несколько лет в парадигме лечения МЛУ ТБ произошли многообещающие сдвиги: новые препараты показали активность против Mycobacterium tuberculosis (MBT), а несколько коротких схем лечения МЛУ ТБ показали многообещающие результаты. Целью данного комплексного обзора является обобщение рекомендуемых ВОЗ схем лечения МЛУ ТБ, а также изложение новых взглядов на лечение пациентов с МЛУ ТБ

NMR spectroscopic investigations on the successive implementation of nickel and zinc ions to a NacNac-dibenzofuran-Br ligand precursor

The ligand precursor HNacNac-dibenzofuran-Br, LH, was synthesized by the condensation of 6-bromo-4-dibenzofuranamine and 4-(N-(mesityl)amino)pent-3-en-2-one with the aim of preparing heterodinuclear nickel/zinc complexes in two successive steps. Reacting LH with Zn(HMDS)2, Zn(C6F5)2 and Zn(C2H5)2 led to the respective X-Zn-NacNac-dibenzofuran-Br complexes (X=HMDS (2), C6F5 (3), Et (4)). However, in case of 2 and 3 the subsequent treatment with Ni(COD)2/TMEDA did not lead to any conversion, probably as the steric bulk imposed by the NacNac-Zn-X entities was too high. 4 did react with Ni(COD)2/TMEDA, likely in the envisaged manner, but apparently the targeted product complex Et-Zn-NacNac-dibenzofuran-Ni(TMEDA)Br, once formed, immediately reacts further via a Negishi coupling reaction, so that Br-Zn-NacNac-dibenzofuran-Et (5) is formed. The reaction of 4 with triethylammonium bromide led to the formation of the Br-Zn-NacNac-dibenzofuran-Br (6) complex that could be reacted with Ni(COD)2/TMEDA successfully. All attempts to purify the product led to Zn(NacNac-dibenzofuran-Ni(TMEDA)Br)2, which is insoluble in THF and thus drives a dismutation reaction.Peer Reviewe

3D-bioengineering of the conventional outflow tract for high throughput drug or gene transfer screening for glaucoma treatment

Among ocular pathologies, glaucoma remains the second leading cause of blindness. The molecular mechanisms that lead to glaucoma have been attributed to damage of the conventional outflow tract. Conventional outflow tissues, a composite of the trabecular meshwork and the Schlemm\u27s canal, regulate and maintain homeostatic responses of aqueous humor outflow. In glaucoma, drainage of aqueous humor into the Schlemm\u27s canal is hindered, leading to an increase in intraocular pressure (IOP). That increase in IOP is directly correlated with retinal ganglion cell death, eliminating the relay of visual information to the thalamus and visual cortex, leading to blindness. Although disturbance in the conventional outflow tract has been implicated as the cause of glaucoma, a mechanism remains to be elucidated. In addition, there are no drugs targeting this structure implicated as the cause of glaucoma. This is, in part, due to limits in our understanding of the pathology at the molecular level and lack of an in vitro model system for outflow studies. Currently, anterior segments of animal or human cadaver eyes are used to study the outflow facility and test the effects of medications on the trabecular meshwork (TM), but these perfusions are cumbersome and expensive, making them impractical for high-throughput screening

El impacto del costo en la rentabilidad de la empresa Laboratorio Farmacéutico Peruano S.R.L. Lima 2021

En este trabajo de investigación se busca demostrar el impacto de los costos en la rentabilidad; la empresa Farmacéutico Peruano S.R.L. en su proceso de producción es importante evitar el uso excesivo de recursos, así se podrá aprovechar al máximo cada recurso lo cual nos dará mejores resultados, una correcta determinación del precio de venta se verá reflejada en la ganancia obtenida en cada periodo, el manejo de la administración y su toma de decisiones es fundamental, cada área dentro de la empresa debe contar con el conocimiento y la capacitación para un desempeño optimo el cual se verá reflejado en la rentabilidad que se obtenga en cada perdido, es importante estar pendiente del comportamiento y de los factores que cambian constantemente, finalizamos que es debemos identificar los costos innecesarios y eliminarlos para que no perjudiquen el desempeño de la rentabilidad. La investigación aplicada – descriptivo; el diseño es de tipo, no experimental – trasversal y descriptivo simple. La población está conformada por 26 personas encargados del área de gerencia, personal de compras, contabilidad, producción, facturación, ventas y almacén. Y la muestra está conformado por 26 personas. El tipo de muestra fue probabilístico. Las técnicas para recopilación de datos fue la encuesta. El instrumento fue el cuestionario. Se aplico las técnicas de procesamiento de datos. Se aplicó las técnicas de procesamiento de datos: ordenamiento y clasificación, registro manual, proceso computarizado con Excel. El resultado más relevante es que el 90 por ciento de los encuestados acepta como el costo impacta en la rentabilidadThis research work seeks to demonstrate the impact of costs on profitability; the Peruvian pharmaceutical company S.R.L. In its production process, it is important to avoid the excessive use of resources, so that each resource can be used to the maximum, which will give us better results, a correct determination of the sale price will be reflected in the profit obtained in each period, the management of the administration and its decision making is fundamental, each area within the company must have the knowledge and training for optimal performance which will be reflected in the profitability obtained in each loss, it is important to be aware of the behavior and Of the constantly changing factors, we concluded that it is necessary to identify unnecessary costs and eliminate them so that they do not harm the profitability performance. Applied research – descriptive; the design is of type, not experimental - cross-sectional and simple descriptive. The population is made up of 26 people in charge of the management area, purchasing personnel, accounting, production, billing, sales and warehouse. And the sample is made up of 26 people. The type of sample was probabilistic The techniques for data collection was the survey. The instrument was the questionnaire. Data processing techniques were applied. Data processing techniques were applied: ordering and classification, manual registration, computerized process with Excel. The most relevant result is that 90 percent of those surveyed accept how cost impacts profitability