CMB temperature anisotropies from third order gravitational perturbations

In this paper we present a complete computation of the Cosmic Microwave Background (CMB) anisotropies up to third order from gravitational perturbations accounting for scalar, vector and tensor perturbations. We then specify our results to the large scale limit, providing the evolution of the gravitational potentials in a flat universe filled with matter and cosmological constant which characterizes the Integrated Sachs-Wolfe effect. As a byproduct in the large scale approximation we are able to give non-perturbative solutions for the photon geodesic equations. Our results are the first step to provide a complete theoretical prediction for cubic non-linearities which are particularly relevant for characterizing the level of non-Gaussianity in the CMB through the detection of the four-point angular connected correlation function (trispectrum). For this purpose we also allow for generic initial conditions due to primordial non-Gaussianity.Comment: 19 pages, LateX file; typos corrected; some corrections made and several consistency checks performed regarding Eqs.(2.18); (2.28)-(2.29) and Eqs.(3.8)-(3.24) and Eq.(4.2). Version accepted for publication in JCA

Quantum test of the equivalence principle for atoms in superpositions of internal energy eigenstates

The Einstein Equivalence Principle (EEP) has a central role in the understanding of gravity and space-time. In its weak form, or Weak Equivalence Principle (WEP), it directly implies equivalence between inertial and gravitational mass. Verifying this principle in a regime where the relevant properties of the test body must be described by quantum theory has profound implications. Here we report on a novel WEP test for atoms. A Bragg atom interferometer in a gravity gradiometer configuration compares the free fall of rubidium atoms prepared in two hyperfine states and in their coherent superposition. The use of the superposition state allows testing genuine quantum aspects of EEP with no classical analogue, which have remained completely unexplored so far. In addition, we measure the Eotvos ratio of atoms in two hyperfine levels with relative uncertainty in the low $10^{-9}$, improving previous results by almost two orders of magnitude.Comment: Accepted for publication in Nature Communicatio

C4BQ0: a genetic marker of familial HCV-related liver cirrhosis.

Source Department of Medicine and Pneumology, V Cervello Hospital, Via Trabucco 180, 90146 Palermo, Italy. [email protected] Abstract BACKGROUND AND METHODS: Host may have a role in the evolution of chronic HCV liver disease. We performed two cross-sectional prospective studies to evaluate the prevalence of cirrhosis in first degree relatives of patients with cirrhosis and the role of two major histocompatibility complex class III alleles BF and C4 versus HCV as risk factors for familial clustering. FINDINGS: Ninety-three (18.6%) of 500 patients with cirrhosis had at least one cirrhotic first degree relative as compared to 13 (2.6%) of 500 controls, (OR 7.38; CI 4.21-12.9). C4BQ0 was significantly more frequent in the 93 cirrhotic patients than in 93 cirrhotic controls without familiarity (Hardy-Weinberg equilibrium: chi2 5.76, P = 0.016) and in 20 families with versus 20 without aggregation of HCV related cirrhosis (29.2% versus 11.3%, P = 0.001); the association C4BQ0-HCV was found almost only in cirrhotic patients with a family history of liver cirrhosis. CONCLUSIONS: Our studies support the value of C4BQ0 as a risk indicator of familial HCV related cirrhosis

Timing the millisecond pulsars in 47 Tucanae

In the last 10 years 20 millisecond pulsars have been discovered in the globular cluster 47 Tucanae. Hitherto, only 3 of these had published timing solutions. Here we improve upon these 3 and present 12 new solutions. These measurements can be used to determine a variety of physical properties of the pulsars and of the cluster. The 15 pulsars have positions determined with typical uncertianties of only a few milliarcsec and they are all located within 1.2 arcmin of the cluster centre. We have also measured the proper motions of 5 of the pulsars, which are consistent with the proper motion of 47 Tuc based on Hipparcos data. The period derivatives measured for many of the pulsars are dominated by the dynamical effects of the cluster gravitational field, and are used to constrain the surface mass density of the cluster. All pulsars have characteristic ages T > 170 Myr and magnetic fields B < 2.4e9 Gauss, and the average T > 1 Gyr. We have measured the rate of advance of periastron for the binary pulsar J0024-7204H, implying a total system mass 1.4+-0.8 solar masses.Comment: 17 pages, 11 included figures, accepted for publication in MNRA

Robust quantum entanglement generation and generation-plus-storage protocols with spin chains

Reliable quantum communication and/or processing links between modules are a necessary building block for various quantum processing architectures. Here we consider a spin-chain system with alternating strength couplings and containing three defects, which impose three domain walls between topologically distinct regions of the chain. We show that - in addition to its useful, high-fidelity, quantum state transfer properties - an entangling protocol can be implemented in this system, with optional localization and storage of the entangled states. We demonstrate both numerically and analytically that, given a suitable initial product-state injection, the natural dynamics of the system produces a maximally entangled state at a given time. We present detailed investigations of the effects of fabrication errors, analyzing random static disorder both in the diagonal and off-diagonal terms of the system Hamiltonian. Our results show that the entangled state formation is very robust against perturbations of up to ∼10% the weaker chain coupling, and also robust against timing injection errors. We propose a further protocol, which manipulates the chain in order to localize and store each of the entangled qubits. The engineering of a system with such characteristics would thus provide a useful device for quantum information processing tasks involving the creation and storage of entangled resources