43,086 research outputs found
Low-temperture electrostatic silicon-to-silicon seals using sputtered borosilicate glass
Silicon members are hermetically sealed to each other. Process produces no measurable deformation of silicon surfaces and is compatible with package designs of tight tolerance. Seals have been made with glass coatings in 10-mm to 20-mm thickness range without any prior annealing of coated silicon substrates
A helium-3 refrigerator employing capillary confinement of liquid cryogen
A condensation refrigerator suitable for operation in a zero gravity space environment was constructed. The condensed liquid refrigerant is confined by surface tension inside a porous metal matrix. Helium-4 and helium-3 gases were condensed and held in a copper matrix. Evaporative cooling of confined liquid helium-4 resulted in a temperature of 1.4K. Using a zeolite adsorption pump external to the cryostat, a temperature of 0.6 K was achieved through evaporative cooling of liquid helium-3. The amount of time required for complete evaporation of a controlled mass of liquid helium-4 contained in the copper matrix was measured as a function of the applied background power. For heating powers below 18 mW the measured times are consistent with the normal boiling of the confined volume of liquid refrigerant. At background powers above 18 mW the rapid rise in the temperature of the copper matrix the signature of the absence of confined liquid occurs in a time a factor of two shorter than that expected on the basis of an extrapolation of the low power data
Sepsis caused by bloodstream infection in patients in the intensive care unit: the impact of inactive empiric antimicrobial therapy on outcome
Background:
Sepsis is one of the leading causes of death in the UK.
Aims:
The aims of this study were to identify the rate of inactive antimicrobial therapy (AMT) in the ICU and whether inactive AMT had an effect on in hospital mortality, ICU mortality, 90-day mortality and length of hospital stay. Additionally, we wanted to identify risk factors for receiving inactive AMT.
Methods:
This was a retrospective observational study conducted at Glasgow Royal Infirmary ICU between January 2010 and December 2013, with 12,000 blood cultures taken over this time period, of which n=127 were deemed clinically significant. Multivariate logistic regression was used to identify risk factors independently associated with mortality. To identify risk factors for receiving inactive AMT a univariable and a subsequent multivariate analysis was constructed.
Results:
The rate of inactive AMT was 47% (n =60). Our multivariate analysis showed that receiving antibiotics within the first 24 hours of ICU admission led to a reduced mortality (RR 1.70; 95% CI 1.19-2.44.) Furthermore, it showed that severity of illness (as defined by SIRS criteria sepsis vs septic shock) increased mortality (OR 9.87; 95% CI 1.73-55.5). However, inactive AMT did not increase mortality (OR 1.07; 95% CI 0.47-2.41) or length of hospital stay (53.2 vs 69.1 days p=0.348.) We identified fungal bloodstream infection as a risk factor for receiving inactive AMT (OR 5.10;95% CI 1.29-20.14.
Conclusion:
Mortality from sepsis is influenced by multiple factors. We were unable to demonstrates that inactive AMT had an effect on mortality in sepsis
Lepton Flavor Violation and Supersymmetric Dirac Leptogenesis
Dirac leptogenesis (or Dirac neutrinogenesis), in which neutrinos are purely
Dirac particles, is an interesting alternative to the standard leptogenesis
scenario. In its supersymmetric version, the modified form of the
superpotential required for successful baryogenesis contributes new,
generically non-flavor-diagonal terms to the slepton and sneutrino mass
matrices. In this work, we examine how current experimental bounds on
flavor-changing effects in the lepton sector (and particularly the bound on Mu
-> e Gamma) constrain Dirac leptogenesis and we find that it is capable of
succeeding with superpartner masses as low as 100 GeV. For such light scalars
and electroweakinos, upcoming experiments such as MEG are generically expected
to observe signals of lepton flavor violation.Comment: 15 pages, 4 figures, corrected parametric dependance on leading LFV
term, figure 2 and discussion modified accordingly, conclusions unchange
Mathematical Properties of a Class of Four-dimensional Neutral Signature Metrics
While the Lorenzian and Riemanian metrics for which all polynomial scalar
curvature invariants vanish (the VSI property) are well-studied, less is known
about the four-dimensional neutral signature metrics with the VSI property.
Recently it was shown that the neutral signature metrics belong to two distinct
subclasses: the Walker and Kundt metrics. In this paper we have chosen an
example from each of the two subcases of the Ricci-flat VSI Walker metrics
respectively.
To investigate the difference between the metrics we determine the existence
of a null, geodesic, expansion-free, shear-free and vorticity-free vector, and
classify these spaces using their infinitesimal holonomy algebras. The
geometric implications of the holonomy algebras are further studied by
identifying the recurrent or covariantly constant null vectors, whose existence
is required by the holonomy structure in each example. We conclude the paper
with a simple example of the equivalence algorithm for these pseudo-Riemannian
manifolds, which is the only approach to classification that provides all
necessary information to determine equivalence.Comment: 18 page
Phenomenology of Dirac Neutrinogenesis in Split Supersymmetry
In Split Supersymmetry scenarios the possibility of having a very heavy
gravitino opens the door to alleviate or completely solve the worrisome
"gravitino problem'' in the context of supersymmetric baryogenesis models. Here
we assume that the gravitino may indeed be heavy and that Majorana masses for
neutrinos are forbidden as well as direct Higgs Yukawa couplings between left
and right handed neutrinos. We investigate the viability of the mechansim known
as Dirac leptogenesis (or neutrinogenesis), both in solving the baryogenesis
puzzle and explaining the observed neutrino sector phenomenology. To
successfully address these issues, the scenario requires the introduction of at
least two new heavy fields. If a hierarchy among these new fields is
introduced, and some reasonable stipulations are made on the couplings that
appear in the superpotential, it becomes a generic feature to obtain the
observed large lepton mixing angles. We show that in this case, it is possible
simultaneously to obtain both the correct neutrino phenomenology and enough
baryon number, making thermal Dirac neutrinogenesis viable. However, due to
cosmological constraints, its ability to satisfy these constraints depends
nontrivially on model parameters of the overall theory, particularly the
gravitino mass. Split supersymmetry with m_{3/2} between 10^{5} and 10^{10} GeV
emerges as a "natural habitat" for thermal Dirac neutrinogenesis.Comment: 37 pages, 8 figure
Bilingual, digital, audio-visual training modules improve technical knowledge of feedlot and dairy workers
Two studies were conducted to determine the effectiveness of digital multimedia modules as training tools for animal care workers. Employees at a commercial feedlot (n = 17) and a commercial dairy (n = 10) were asked to independently complete a 10-question quiz prior to and following viewing of training modules. Module topics in the feedlot were proper handling of non-ambulatory animals and humane methods of euthanasia; modules were administered to the workers, as a group, in either English (n = 7) or Spanish (N = 10), depending on previously indicated worker preference. Modules addressing dairy cattle health practices and dairy cattle handling were presented to the dairy care workers who had a preference for learning in either English (n = 7) or Spanish (n = 3). For feedlot workers, post-test scores were improved by 28% after viewing the modules compared to pre-test scores (74% vs. 58%; P 0.30) between language, topic, and between-test variation, indicating that the modules were equally effective at information delivery to both audiences in both languages. For the dairy workers, test scores improved by 27% from pre-viewing to post-viewing (73% vs. 92%; P < 0.01); there was an interaction between the effect of module and language preference (P < 0.01) indicating that although scores increased for both of the topic areas for the English-speaking workers, only the score for the animal health topic increased for the Spanish-speaking workers. Regardless of nationality, level of formal education, topic, or preferred language, digital media are effective at improving knowledge transfer to animal care professionals
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