1,232 research outputs found
Policies and institutions to enhance the impact of irrigation development in mixed crop-livestock systemsLength: pp.168-184
Irrigation managementInstitutional developmentPolicyCrop productionLivestockWater demandIrrigation waterSmall scale systemsInvestmentFarmer managed irrigation systemsPovertyFarmersGenderWater users’ associations
Non-destructive cavity QED probe of Bloch oscillations in a gas of ultracold atoms
We describe a scheme for probing a gas of ultracold atoms trapped in an
optical lattice and moving in the presence of an external potential. The probe
is non-destructive and uses the existing lattice fields as the measurement
device. Two counter-propagating cavity fields simultaneously set up a
conservative lattice potential and a weak quantum probe of the atomic motion.
Balanced heterodyne detection of the probe field at the cavity output along
with integration in time and across the atomic cloud yield information about
the atomic dynamics in a single run. The scheme is applied to a measurement of
the Bloch oscillation frequency for atoms moving in the presence of the local
gravitational potential. Signal-to-noise ratios are estimated to be as high as
.Comment: 8 pages, 6 figures, submitted to Phys. Rev.
Quantized Vortex States of Strongly Interacting Bosons in a Rotating Optical Lattice
Bose gases in rotating optical lattices combine two important topics in
quantum physics: superfluid rotation and strong correlations. In this paper, we
examine square two-dimensional systems at zero temperature comprised of
strongly repulsive bosons with filling factors of less than one atom per
lattice site. The entry of vortices into the system is characterized by jumps
of 2 pi in the phase winding of the condensate wavefunction. A lattice of size
L X L can have at most L-1 quantized vortices in the lowest Bloch band. In
contrast to homogeneous systems, angular momentum is not a good quantum number
since the continuous rotational symmetry is broken by the lattice. Instead, a
quasi-angular momentum captures the discrete rotational symmetry of the system.
Energy level crossings indicative of quantum phase transitions are observed
when the quasi-angular momentum of the ground-state changes.Comment: 12 Pages, 13 Figures, Version
All-optical 3D atomic loops generated with Bessel light fields
The propagation invariance of Bessel beams as well as their transversal
structure are used to perform a comparative analysis of their effect on cold
atoms for four different configurations and combinations thereof. We show that,
even at temperatures for which the classical description of the atom center of
mass motion is valid, the interchange of momentum, energy and orbital angular
momentum between light and atoms yields efficient tools for all-optical
trapping, transporting and, in general, manipulating the state of motion of
cold atoms.Comment: 13 pages, 9 figure
Abnormal prion protein in the retina of the most commonly occurring subtype of sporadic Creutzfeldt-Jakob disease
Background: Involvement of the eye has been reported in patients with variant Creutzfeldt-Jakob disease (vCJD), but there is disagreement on whether retinal involvement occurs in sporadic Creutzfeldt-Jakob disease (sCJD). Methods: Western blotting, paraffin embedded tissue blotting, and immunohistochemistry were used to test whether the abnormal form of the prion protein (PrP(Sc)) accumulates to detectable levels in the eye in a case of the most common subtype of sCJD (MM1). Results: Low levels of PrP(Sc) were detectable in the retina, localised to the plexiform layers of the central retina. PrP(Sc) was not detectable in other ocular tissues. Conclusions: The abnormal form of the prion protein is present in the retina in the most common sCJD subtype (MM1), albeit at levels lower than those found previously in vCJD and in sCJD of the VV2 subtype
Trends in variability and extremes of rainfall and temperature in the cattle corridor of Uganda
A study was conducted to determine trends of variability and extremes in rainfall and temperature in order to inform stakeholder’s decisions in planning for appropriate adaptation strategies to climate change. Daily rainfall and temperature data sets from 1961 to 2013 were used. Data were subjected to trend analysis using non-parametric Mann-Kendall tests while rainfall and temperature extremes were derived using RClimdex software. Coefficient of variation (CV) in annual rainfall was 25.3, 12.9 and 16.3 % for Mbarara, Masindi and Soroti respectively. Mean daily maximum temperatures were 26.7, 29.6 and 30.8 oC for Mbarara, Masindi and Soroti respectively. Annual total wet days were increasing but not significant (P>0.05). Consecutive wet days (CWD) were increasing only in Mbarara while consecutive dry days, CDDs revealed weak declining trends in Mbarara and stronger significant increasing trends in Soroti (P<0.05). The number of hot days (TX90p) and warm nights (TN90p) was significantly increasing (P< 0.05) in Mbarara and Masindi. The number of warmest nights (TNx) and hottest days (TXx) was also significantly increasing (P<0.05). Mean diurnal temperature range, DTR showed significant decreasing trends in Mbarara and Masindi (P<0.05) while in Soroti it was significantly increasing. The observed increasing temperatures, coupled with declining CWDs and increasing CDDs will most likely result into increased heat stress to livestock, drying of most surface water sources and changes in pasture species composition thus causing a decline in livestock productivity
Surface Core Level Shifts of Clean and Oxygen Covered Ru(0001)
We have performed high resolution XPS experiments of the Ru(0001) surface,
both clean and covered with well-defined amounts of oxygen up to 1 ML coverage.
For the clean surface we detected two distinct components in the Ru 3d_{5/2}
core level spectra, for which a definite assignment was made using the high
resolution Angle-Scan Photoelectron Diffraction approach. For the p(2x2),
p(2x1), (2x2)-3O and (1x1)-O oxygen structures we found Ru 3d_{5/2} core level
peaks which are shifted up to 1 eV to higher binding energies. Very good
agreement with density functional theory calculations of these Surface Core
Level Shifts (SCLS) is reported. The overriding parameter for the resulting Ru
SCLSs turns out to be the number of directly coordinated O atoms. Since the
calculations permit the separation of initial and final state effects, our
results give valuable information for the understanding of bonding and
screening at the surface, otherwise not accessible in the measurement of the
core level energies alone.Comment: 16 pages including 10 figures. Submitted to Phys. Rev. B. Related
publications can be found at http://www.fhi-berlin.mpg.de/th/paper.htm
Stability of sub-surface oxygen at Rh(111)
Using density-functional theory (DFT) we investigate the incorporation of
oxygen directly below the Rh(111) surface. We show that oxygen incorporation
will only commence after nearly completion of a dense O adlayer (\theta_tot =
1.0 monolayer) with O in the fcc on-surface sites. The experimentally suggested
octahedral sub-surface site occupancy, inducing a site-switch of the on-surface
species from fcc to hcp sites, is indeed found to be a rather low energy
structure. Our results indicate that at even higher coverages oxygen
incorporation is followed by oxygen agglomeration in two-dimensional
sub-surface islands directly below the first metal layer. Inside these islands,
the metastable hcp/octahedral (on-surface/sub-surface) site combination will
undergo a barrierless displacement, introducing a stacking fault of the first
metal layer with respect to the underlying substrate and leading to a stable
fcc/tetrahedral site occupation. We suggest that these elementary steps,
namely, oxygen incorporation, aggregation into sub-surface islands and
destabilization of the metal surface may be more general and precede the
formation of a surface oxide at close-packed late transition metal surfaces.Comment: 9 pages including 9 figure files. Submitted to Phys. Rev. B. Related
publications can be found at http://www.fhi-berlin.mpg.de/th/paper.htm
Improved outcomes for hepatic trauma in England and Wales over a decade of trauma and hepatobiliary surgery centralisation
Background: Over the last decade trauma services have undergone a reconfiguration in England and Wales. The objective is to describe the epidemiology, management and outcomes for liver trauma over this period and examine factors predicting survival. Methods: Patients sustaining hepatic trauma were identified using the Trauma Audit and Research Network database. Demographics, management and outcomes were assessed between January 2005 and December 2014 and analysed over five, 2-year study periods. Independent predictor variables for the outcome of liver trauma were analysed using multiple logistic regression. Results: 4368 Patients sustained hepatic trauma (with known outcome) between January 2005 and December 2014. Median age was 34 years (interquartile range 23–49). 81% were due to blunt and 19% to penetrating trauma. Road traffic collisions were the main mechanism of injury (58.2%). 241 patients (5.5%) underwent liver-specific surgery. The overall 30-day mortality rate was 16.4%. Improvements were seen in early consultant input, frequency and timing of computed tomography (CT) scanning, use of tranexamic acid and 30-day mortality over the five time periods. Being treated in a unit with an on-site HPB service increased the odds of survival (odds ratio 3.5, 95% confidence intervals 2.7–4.5). Conclusions: Our study has shown that being treated in a unit with an on-site HPB service increased the odds of survival. Further evaluation of the benefits of trauma and HPB surgery centralisation is warranted
Common Variants at 10 Genomic Loci Influence Hemoglobin A(1C) Levels via Glycemic and Nonglycemic Pathways
OBJECTIVE Glycated hemoglobin (HbA1c), used to monitor and diagnose diabetes, is influenced by average glycemia over a 2- to 3-month period. Genetic factors affecting expression, turnover, and abnormal glycation of hemoglobin could also be associated with increased levels of HbA1c. We aimed to identify such genetic factors and investigate the extent to which they influence diabetes classification based on HbA1c levels.
RESEARCH DESIGN AND METHODS We studied associations with HbA1c in up to 46,368 nondiabetic adults of European descent from 23 genome-wide association studies (GWAS) and 8 cohorts with de novo genotyped single nucleotide polymorphisms (SNPs). We combined studies using inverse-variance meta-analysis and tested mediation by glycemia using conditional analyses. We estimated the global effect of HbA1c loci using a multilocus risk score, and used net reclassification to estimate genetic effects on diabetes screening.
RESULTS Ten loci reached genome-wide significant association with HbA1c, including six new loci near FN3K (lead SNP/P value, rs1046896/P = 1.6 × 10−26), HFE (rs1800562/P = 2.6 × 10−20), TMPRSS6 (rs855791/P = 2.7 × 10−14), ANK1 (rs4737009/P = 6.1 × 10−12), SPTA1 (rs2779116/P = 2.8 × 10−9) and ATP11A/TUBGCP3 (rs7998202/P = 5.2 × 10−9), and four known HbA1c loci: HK1 (rs16926246/P = 3.1 × 10−54), MTNR1B (rs1387153/P = 4.0 × 10−11), GCK (rs1799884/P = 1.5 × 10−20) and G6PC2/ABCB11 (rs552976/P = 8.2 × 10−18). We show that associations with HbA1c are partly a function of hyperglycemia associated with 3 of the 10 loci (GCK, G6PC2 and MTNR1B). The seven nonglycemic loci accounted for a 0.19 (% HbA1c) difference between the extreme 10% tails of the risk score, and would reclassify ∼2% of a general white population screened for diabetes with HbA1c.
CONCLUSIONS GWAS identified 10 genetic loci reproducibly associated with HbA1c. Six are novel and seven map to loci where rarer variants cause hereditary anemias and iron storage disorders. Common variants at these loci likely influence HbA1c levels via erythrocyte biology, and confer a small but detectable reclassification of diabetes diagnosis by HbA1c
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