10,814 research outputs found
The Potential Applications of Optical Dating to the Sandy Uplands of East Texas and Northwest Louisiana
The fine, sandy soils of East Texas and Northwest Louisiana have been the source of archaeological debate for some time. This discourse concerns the mode of burial of cultural material in the easily eroded soils and the mechanics of recent (Holocene) landform evolution. Because these deposits are typically well-drained, organic matter does not preserve well, thus hindering the dating of the geomorphic events that figure prominently in their development and the prehistoric occupations which lie buried throughout uplands of this region. A relatively new dating technique, optical dating, has much to offer this region and the archaeological community as it measures the period of time that has elapsed since sand grains were last exposed to sunlight. Hence, it directly dates the time of sediment transportation and deposition. This method is therefore applicable to a number of archaeological and geomorphic processes which may not be dated by traditional methods, owing to the lack of organic matter suitable for radiocarbon dating. In geomorphic contexts, optical dating may be preferred over radiocarbon as it directly dates the time of sedimentation rather than the age of organic matter in features such as buried soils that may be significantly different from the geomorphic event which fossilized the soil
Representations and Properties of Generalized Statistics
A generalization of statistics is proposed and developed. The
generalized quantum statistics is completely specified by a set of
Jacobson generators satisfying a set of triple algebraic relations.
Fock-Hilbert representations and Bargmann-Fock realizations are derived.Comment: 12 pages, to appear in IJMPA (2006
The role of biofilms in subsurface transport processes
Landfill and radioactive waste disposal risk assessments focus on contaminant transport and are principally concerned with understanding the movement of gas, water and solutes through engineered barriers and natural groundwater systems. However, microbiological activity can affect transport processes, changing the chemical and physical characteristics of the subsurface environment. Such effects are generally caused by biofilms attached to rock surfaces. Currently most existing transport models have to introduce additional assumptions about the relationships between the microbial growth and changes to the porosity and permeability. These relationships are particularly poorly understood. This paper reviews recent experimental work directed at the development of biofilms and their influence on subsurface flow and the transport of contaminants in intergranular and fracture porosity flow systems. The results are then discussed in terms of a more complex conceptual model
A Model for Classical Space-time Co-ordinates
Field equations with general covariance are interpreted as equations for a
target space describing physical space time co-ordinates, in terms of an
underlying base space with conformal invariance. These equations admit an
infinite number of inequivalent Lagrangian descriptions. A model for
reparametrisation invariant membranes is obtained by reversing the roles of
base and target space variables in these considerations.Comment: 9 pages, Latex. This was the basis of a talk given at the Argonne
National Laboratory 1996 Summer Institute : Topics on Non-Abelian Duality
June 27-July 1
Virtual patient design : exploring what works and why : a grounded theory study
Objectives:
Virtual patients (VPs) are online representations of clinical cases used in medical education. Widely adopted, they are well placed to teach clinical reasoning skills. International technology standards mean VPs can be created, shared and repurposed between institutions. A systematic review has highlighted the lack of evidence to support which of the numerous VP designs may be effective, and why. We set out to research the influence of VP design on medical undergraduates.
Methods:
This is a grounded theory study into the influence of VP design on undergraduate medical students. Following a review of the literature and publicly available VP cases, we identified important design properties. We integrated them into two substantial VPs produced for this research. Using purposeful iterative sampling, 46 medical undergraduates were recruited to participate in six focus groups. Participants completed both VPs, an evaluation and a 1-hour focus group discussion. These were digitally recorded, transcribed and analysed using grounded theory, supported by computer-assisted analysis. Following open, axial and selective coding, we produced a theoretical model describing how students learn from VPs.
Results:
We identified a central core phenomenon designated ‘learning from the VP’. This had four categories: VP Construction; External Preconditions; Student–VP Interaction, and Consequences. From these, we constructed a three-layer model describing the interactions of students with VPs. The inner layer consists of the student's cognitive and behavioural preconditions prior to sitting a case. The middle layer considers the VP as an ‘encoded object’, an e-learning artefact and as a ‘constructed activity’, with associated pedagogic and organisational elements. The outer layer describes cognitive and behavioural change.
Conclusions:
This is the first grounded theory study to explore VP design. This original research has produced a model which enhances understanding of how and why the delivery and design of VPs influence learning. The model may be of practical use to authors, institutions and researchers
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Brainstem atrophy in focal epilepsy destabilizes brainstem-brain interactions: Preliminary findings.
BACKGROUND: MR Imaging has shown atrophy in brainstem regions that were linked to autonomic dysfunction in epilepsy patients. The brainstem projects to and modulates the activation state of several wide-spread cortical/subcortical regions. The goal was to investigate 1. Impact of brainstem atrophy on gray matter connectivity of cortical/subcortical structures and autonomic control. 2. Impact on the modulation of cortical/subcortical functional connectivity.
METHODS: 11 controls and 18 patients with non-lesional focal epilepsy (FE) underwent heart rate variability (HRV) measurements and a 3 T MRI (T1 in all subjects, task-free fMRI in 7 controls/ 12 FE). The brainstem was extracted, and atrophy assessed using deformation-based-morphometry. The age-corrected z-scores of the mean Jacobian determinants were extracted from 71 5x5x5 mm grids placed in brainstem regions associated with autonomic function. Cortical and non-brainstem subcortical gray matter atrophy was assessed with voxel-based-morphometry and mean age corrected z-scores of the modulated gray matter volumes extracted from 380 cortical/subcortical rois. The profile similarity index was used to characterize the impact of brainstem atrophy on gray matter connectivity. The fMRI was preprocessed in SPM12/Conn17 and the BOLD signal extracted from 398 ROIs (16 brainstem). A dynamic task-free analysis approach was used to identify activation states. Connectivity HRV relationship were assessed with Spearman rank correlations.
RESULTS: HRV was negatively correlated with reduced brainstem right hippocampus/parahippocampus gray matter connectivity in controls (p \u3c .05, FDR) and reduced brainstem to right parietal cortex, lingual gyrus, left hippocampus/amygdala, parahippocampus, temporal pole, and bilateral anterior thalamus connectivity in FE (p \u3c .05, FDR). Dynamic task-free fMRI analysis identified 22 states. The strength of the functional brainstem/cortical connectivity of state 15 was negatively associated with HRV (r = -0.5, p = .03) and positively with decreased brainstem-cortical (0.49, p = .03) gray matter connectivity.
CONCLUSION: The findings of this small pilot study suggest that impaired brainstem-cortex gray matter connectivity in FE negatively affects the brainstem\u27s ability to control cortical activation
Preserving the palaeoenvironmental record in Drylands: Bioturbation and its significance for luminescence-derived chronologies
Luminescence (OSL) dating has revolutionised the understanding of Late Pleistocene dryland activity. However,
one of the key assumptions for this sort of palaeoenvironmental work is that sedimentary sequences have been
preserved intact, enabling their use as proxy indicators of past changes. This relies on stabilisation or burial
soon after deposition and a mechanism to prevent any subsequent re-mobilisation. As well as a dating
technique OSL, especially at the single grain level, can be used to gain an insight into post-depositional
processes that may distort or invalidate the palaeoenvironmental record of geological sediment sequences.
This paper explores the possible impact of bioturbation (the movement of sediment by flora and fauna) on
luminescence derived chronologies from Quaternary sedimentary deposits in Texas and Florida (USA) which
have both independent radiocarbon chronologies and archaeological evidence. These sites clearly illustrate the
ability of bioturbation to rejuvenate ancient weathered sandy bedrock and/or to alter depositional stratigraphies
through the processes of exhumation and sub-surface mixing of sediment. The use of multiple OSL replicate
measurements is advocated as a strategy for checking for bioturbated sediment. Where significant OSL
heterogeneity is found, caution should be taken with the derived OSL ages and further measurements at the
single grain level are recommended. Observations from the linear dunes of the Kalahari show them to have no
bedding structure and to have OSL heterogeneity similar to that shown from the bioturbated Texan and Florida
sites. The Kalahari linear dunes could have therefore undergone hitherto undetected post-depositional sediment
disturbance which would have implications for the established OSL chronology for the region
Feasibility study of an Integrated Program for Aerospace vehicle Design (IPAD). Volume 3: Support of the design process
The user requirements for computer support of the IPAD design process are identified. The user-system interface, language, equipment, and computational requirements are considered
Helical, Angular and Radial Ordering in Narrow Capillaries
To enlighten the nature of the order-disorder and order-order transitions in
block copolymer melts confined in narrow capillaries we analyze peculiarities
of the conventional Landau weak crystallization theory of systems confined to
cylindrical geometry. This phenomenological approach provides a quantitative
classification of the cylindrical ordered morphologies by expansion of the
order parameter spatial distribution into the eigenfunctions of the Laplace
operator. The symmetry of the resulting ordered morphologies is shown to
strongly depend both on the boundary conditions (wall preference) and the ratio
of the cylinder radius and the wave length of the critical order parameter
fluctuations, which determine the bulk ordering of the system under
consideration. In particular, occurrence of the helical morphologies is a
rather general consequence of the imposed cylindrical symmetry for narrow
enough capillaries. We discuss also the ODT and OOT involving some other
simplest morphologies. The presented results are relevant also to other
ordering systems as charge-density waves appearing under addition of an ionic
solute to a solvent in its critical region, weakly charged polyelectrolyte
solutions in poor solvent, microemulsions etc.Comment: 6 pages, 3 figure
Extending the aridity record of the Southwest Kalahari: current problems and future perspectives
An extensive luminescence-based chronological framework has allowed the reconstruction of expansions and contractions of the Kalahari Desert over the last 50 ka. However, this chronology is largely based on near-surface pits and sediment exposures. These are the points on the landscape most prone to reactivation and resetting of the luminescence dating ‘clock’. This is proving to be a limiting feature for extending palaeoenvironmental reconstructions further back in time. One way to obviate this is to sample desert marginal areas that only become active during significant arid phases. An alternative is to find and sample deep stratigraphic exposures. The Mamatwan manganese mine at Hotazel in the SW Kalahari meets both these criteria. Luminescence dating of this site shows the upper sedimentary unit to span at least the last 60 ka with tentative age estimates from underlying cemented aeolian units dating back to the last interglacial and beyond. Results from Mamatwan are comparable to new and previously published data from linear dunes in the SW Kalahari but extend back much further. Analysis of the entire data set of luminescence ages for the SW Kalahari brings out important inferences that suggest that different aeolian forms (1) have been active over different time scales in the past, (2) have different sensitivities to environmental changes and (3) have different time scales over which they record and preserve the palaeoenvironmental record. This implies that future optically stimulated luminescence work and palaeoenvironmental reconstructions must consider both site location and its relationship to desert margins and sediment depositional styles, so that the resolution and duration of the aridity record can be optimally understood
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