1,041 research outputs found

    Two-photon quantum walks in an elliptical direct-write waveguide array

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    Integrated optics provides an ideal test bed for the emulation of quantum systems via continuous-time quantum walks. Here we study the evolution of two-photon states in an elliptic array of waveguides. We characterise the photonic chip via coherent-light tomography and use the results to predict distinct differences between temporally indistinguishable and distinguishable two-photon inputs which we then compare with experimental observations. Our work highlights the feasibility for emulation of coherent quantum phenomena in three-dimensional waveguide structures.Comment: 8 pages, 7 figure

    Submillimeter observations of IRAS and WISE debris disk candidates

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    A set of six debris disk candidates identified with IRAS or WISE excesses were observed at either 350 μm or 450 μm with the Caltech Submillimeter Observatory. Five of the targets – HIP 51658, HIP 68160, HIP 73512, HIP 76375, and HIP 112460 – have among the largest measured excess emission from cold dust from IRAS in the 25–100 μm bands. Single temperature blackbody fits to the excess dust emission of these sources predict 350–450 μm fluxes above 240 mJy. The final target – HIP 73165 – exhibits weak excess emission above the stellar photosphere from WISE measurements at 22 μm, indicative of a population of warm circumstellar dust. None of the six targets were detected, with 3σ upper limits ranging from 51–239 mJy. These limits are significantly below the expected fluxes from SED fitting. Two potential causes of the null detections were explored – companion stars and contamination. To investigate the possible influence of companion stars, imaging data were analyzed from new adaptive optics data from the ARIES instrument on the 6.5 m MMT and archival HST, Gemini NIRI, and POSS/2MASS data. The images are sensitive to all stellar companions beyond a radius of 1–94 AU, with the inner limit depending on the distance and brightness of each target. One target is identified as a binary system, but with a separation too large to impact the disk. While the gravitational effects of a companion do not appear to provide an explanation for the submm upper limits, the majority of the IRAS excess targets show evidence for contaminating sources, based on investigation of higher resolution WISE and archival Spitzer and Herschel images. Finally, the exploratory submm measurements of the WISE excess source suggest that the hot dust present around these targets is not matched by a comparable population of colder, outer dust. More extensive and more sensitive Herschel observations of WISE excess sources will build upon this initial example to further define the characteristics of warm debris disks sources

    Modulation of enhancer looping and differential gene targeting by Epstein-Barr virus transcription factors directs cellular reprogramming

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    Epstein-Barr virus (EBV) epigenetically reprogrammes B-lymphocytes to drive immortalization and facilitate viral persistence. Host-cell transcription is perturbed principally through the actions of EBV EBNA 2, 3A, 3B and 3C, with cellular genes deregulated by specific combinations of these EBNAs through unknown mechanisms. Comparing human genome binding by these viral transcription factors, we discovered that 25% of binding sites were shared by EBNA 2 and the EBNA 3s and were located predominantly in enhancers. Moreover, 80% of potential EBNA 3A, 3B or 3C target genes were also targeted by EBNA 2, implicating extensive interplay between EBNA 2 and 3 proteins in cellular reprogramming. Investigating shared enhancer sites neighbouring two new targets (WEE1 and CTBP2) we discovered that EBNA 3 proteins repress transcription by modulating enhancer-promoter loop formation to establish repressive chromatin hubs or prevent assembly of active hubs. Re-ChIP analysis revealed that EBNA 2 and 3 proteins do not bind simultaneously at shared sites but compete for binding thereby modulating enhancer-promoter interactions. At an EBNA 3-only intergenic enhancer site between ADAM28 and ADAMDEC1 EBNA 3C was also able to independently direct epigenetic repression of both genes through enhancer-promoter looping. Significantly, studying shared or unique EBNA 3 binding sites at WEE1, CTBP2, ITGAL (LFA-1 alpha chain), BCL2L11 (Bim) and the ADAMs, we also discovered that different sets of EBNA 3 proteins bind regulatory elements in a gene and cell-type specific manner. Binding profiles correlated with the effects of individual EBNA 3 proteins on the expression of these genes, providing a molecular basis for the targeting of different sets of cellular genes by the EBNA 3s. Our results therefore highlight the influence of the genomic and cellular context in determining the specificity of gene deregulation by EBV and provide a paradigm for host-cell reprogramming through modulation of enhancer-promoter interactions by viral transcription factors

    Circumstellar discs: What will be next?

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    This prospective chapter gives our view on the evolution of the study of circumstellar discs within the next 20 years from both observational and theoretical sides. We first present the expected improvements in our knowledge of protoplanetary discs as for their masses, sizes, chemistry, the presence of planets as well as the evolutionary processes shaping these discs. We then explore the older debris disc stage and explain what will be learnt concerning their birth, the intrinsic links between these discs and planets, the hot dust and the gas detected around main sequence stars as well as discs around white dwarfs.Comment: invited review; comments welcome (32 pages

    Dynamical Mass Measurement of the Young Spectroscopic Binary V343 Normae AaAb Resolved With the Gemini Planet Imager

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    We present new spatially resolved astrometry and photometry from the Gemini Planet Imager of the inner binary of the young multiple star system V343 Normae, which is a member of the beta Pictoris moving group. V343 Normae comprises a K0 and mid-M star in a ~4.5 year orbit (AaAb) and a wide 10" M5 companion (B). By combining these data with archival astrometry and radial velocities we fit the orbit and measure individual masses for both components of M_Aa = 1.10 +/- 0.10 M_sun and M_Ab = 0.290 +/- 0.018 M_sun. Comparing to theoretical isochrones, we find good agreement for the measured masses and JHK band magnitudes of the two components consistent with the age of the beta Pic moving group. We derive a model-dependent age for the beta Pic moving group of 26 +/- 3 Myr by combining our results for V343 Normae with literature measurements for GJ 3305, which is another group member with resolved binary components and dynamical masses.Comment: 12 pages, 7 figures. Accepted to A

    GPI spectra of HR 8799 c, d, and e from 1.5 to 2.4μ\mum with KLIP Forward Modeling

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    We explore KLIP forward modeling spectral extraction on Gemini Planet Imager coronagraphic data of HR 8799, using PyKLIP and show algorithm stability with varying KLIP parameters. We report new and re-reduced spectrophotometry of HR 8799 c, d, and e in H & K bands. We discuss a strategy for choosing optimal KLIP PSF subtraction parameters by injecting simulated sources and recovering them over a range of parameters. The K1/K2 spectra for HR 8799 c and d are similar to previously published results from the same dataset. We also present a K band spectrum of HR 8799 e for the first time and show that our H-band spectra agree well with previously published spectra from the VLT/SPHERE instrument. We show that HR 8799 c and d show significant differences in their H & K spectra, but do not find any conclusive differences between d and e or c and e, likely due to large error bars in the recovered spectrum of e. Compared to M, L, and T-type field brown dwarfs, all three planets are most consistent with mid and late L spectral types. All objects are consistent with low gravity but a lack of standard spectra for low gravity limit the ability to fit the best spectral type. We discuss how dedicated modeling efforts can better fit HR 8799 planets' near-IR flux and discuss how differences between the properties of these planets can be further explored.Comment: Accepted to AJ, 25 pages, 16 Figure
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