395 research outputs found

    Indicators for comparing performance of irrigated agricultural systems

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    Irrigated farming / Irrigation systems / Indicators / Performance indexes / Financing / Crop production / Water demand / Water requirements / Prices

    Water productivity in Zhanghe Irrigation System: issues of scale

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    Irrigation systemsWater productivityReservoirsWater useWater stressWater conservationRicePaddy fieldsCrop yield

    Real-world emissions from non-road mobile machinery in London

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    The 2016 London atmospheric emissions inventory estimates that, the construction sector contributes 34% of the total PM 10 and 7% of the total NO X – the largest and 5 th largest sources, respectively. Recent on-road light duty diesel vehicle emission tests have shown significant differences between real-world NO X emissions compared with results from laboratory based regulatory tests. The aim of this study was therefore to quantify the ‘real-world’ tail-pipe NO X, CO 2, and particle emissions, for 30 of the most commonly used construction machines in London under normal working conditions. The highest NO X emissions (g/kWh) were from the older engines (Stage III-A ~4.88 g/kWh and III-B ~4.61 g/kWh), these were reduced significantly (~78%) in the newer (Stage IV ~1.05 g/kWh) engines due to more advanced engine management systems and exhaust after treatment. One Stage IV machine emitted NO X similar to a Stage III-B machine, the failure of this SCR was only detectable using PEMS as no warning was given by the machine. Higher NO X conformity factors were observed for Stage IV machines, due to the lower NO X emission standards, which these machines must adhere to. On average, Stage III-B machines (~525 g/kWh) emitted the lowest levels of CO 2 emissions, compared to Stage III-A (~875 g/kWh) and Stage IV (~575 g/kWh) machines. Overall, a statistically significant (~41%) decrease was observed in the CO 2 emissions (g/kWh) between Stage III-A and III-B machines, while no statistically significant difference was found between Stage III-B and IV machines. Particle mass measurements, which were only measured from generators, showed that generators of all engine sizes were within their respective Stage III-A emission standards. A 95% reduction in NO X and 2 orders of magnitude reduction in particle number was observed for a SCR-DPF retrofitted generator, compared to the same generator prior to exhaust gas after-treatment strategy. </p

    Many analysts, one data set: making transparent how variations in analytic choices affect results

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    Twenty-nine teams involving 61 analysts used the same data set to address the same research question: whether soccer referees are more likely to give red cards to dark-skin-toned players than to light-skin-toned players. Analytic approaches varied widely across the teams, and the estimated effect sizes ranged from 0.89 to 2.93 (Mdn = 1.31) in odds-ratio units. Twenty teams (69%) found a statistically significant positive effect, and 9 teams (31%) did not observe a significant relationship. Overall, the 29 different analyses used 21 unique combinations of covariates. Neither analysts’ prior beliefs about the effect of interest nor their level of expertise readily explained the variation in the outcomes of the analyses. Peer ratings of the quality of the analyses also did not account for the variability. These findings suggest that significant variation in the results of analyses of complex data may be difficult to avoid, even by experts with honest intentions. Crowdsourcing data analysis, a strategy in which numerous research teams are recruited to simultaneously investigate the same research question, makes transparent how defensible, yet subjective, analytic choices influence research results

    Synthesis of Learning from a Decade of CGIAR Research Programs

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    The objective of this forward-looking synthesis was to bring together learning from a decade of experience with CGIAR research programs (CRPs), based on existing evaluative evidence. The purpose of this meta-review is to review lessons from the CRP experience to inform the development of future research programs of One CGIAR. The 2021 Synthesis and Lessons Learned from a Decade of CRPs is delivered in response to the request of the CGIAR System Council and aligned with the synthesis terms of reference endorsed by SIMEC in February 2021. The synthesis examined evidence from the two phases of CRP implementation: 2011–2016 and 2017–2019. Four key issues were addressed: (1) patterns and trends between the two phases of CRPs related to the quality of science (QoS) and research for development, achievement of sustainable development outcomes, and management and governance; (2) systemwide issues affecting CRP achievements; (3) recommendations for the future orientation of CGIAR research and innovation; and (4) key evidence gaps and needs for future evaluations. A narrative synthesis approach was used, employing secondary source data from 47 existing evaluations and reviews. External evaluations were systematically coded and analyzed by senior subject matter experts (SMEs) using a standardized analytical framework. A bibliometric trend analysis was carried out, and findings were triangulated against earlier syntheses and validated by members of the Independent Science for Development Council (ISDC), CRP leaders, and expert peer reviewers

    K13 blocks KSHV lytic replication and deregulates vIL6 nad hIL6 expression: A model of lytic replication induced clonal selection in viral oncogenesis

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    Background. Accumulating evidence suggests that dysregulated expression of lytic genes plays an important role in KSHV (Kaposi's sarcoma associated herpesvirus) tumorigenesis. However, the molecular events leading to the dysregulation of KSHV lytic gene expression program are incompletely understood. Methodoloxy/Principal Findings. We have studied the effect of KSHV-encoded latent protein vFLIP K13, a potent activator of the NF-κB pathway, on lytic reactivation of the virus. We demonstrate that K13 antagonizes RTA, the KSHV lytic-regulator, and effectively blocks the expression of lytic proteins, production of infectious virions and death of the infected cells. Induction of lytic replication selects for clones with increased K13 expression and NF-κB activity, while siRNA-mediated silencing of K13 induces the expression of lytic genes. However, the suppressive effect of K13 on RTA-induced lytic genes is not uniform and it falls to block RTA-induced viral IL6 secretion and cooperates with RTA to enhance cellular IL-6 production, thereby dysregulating the lytic gene expression program. Conclusions/Significance. Our results support a model in which ongoing KSHV, lytic replication selects for clones with progressively higher levels of K13 expression and NF-κB activity, which in turn drive KSHV tumorigenesis by not only directly stimulating cellular survival and proliferation, but also indirectly by dysregulating the viral lytic gene program and allowing non-lytic production of growth-promoting viral and cellular genes. Lytic Replication-Induced Clonal Selection (LyRICS) may represent a general mechanism in viral oncogenesis. 2007 Zhao et al

    Data from a pre-publication independent replication initiative examining ten moral judgement effects

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    We present the data from a crowdsourced project seeking to replicate findings in independent laboratories before (rather than after) they are published. In this Pre-Publication Independent Replication (PPIR) initiative, 25 research groups attempted to replicate 10 moral judgment effects from a single laboratory's research pipeline of unpublished findings. The 10 effects were investigated using online/lab surveys containing psychological manipulations (vignettes) followed by questionnaires. Results revealed a mix of reliable, unreliable, and culturally moderated findings. Unlike any previous replication project, this dataset includes the data from not only the replications but also from the original studies, creating a unique corpus that researchers can use to better understand reproducibility and irreproducibility in science

    Competition for water for the food system

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    Although the global agricultural system will need to provide more food for a growing and wealthier population in decades to come, increasing demands for water and potential impacts of climate change pose threats to food systems. We review the primary threats to agricultural water availability, and model the potential effects of increases in municipal and industrial (M&I) water demands, environmental flow requirements (EFRs) and changing water supplies given climate change. Our models show that, together, these factors cause an 18 per cent reduction in the availability of worldwide water for agriculture by 2050. Meeting EFRs, which can necessitate more than 50 per cent of the mean annual run-off in a basin depending on its hydrograph, presents the single biggest threat to agricultural water availability. Next are increases in M&I demands, which are projected to increase upwards of 200 per cent by 2050 in developing countries with rapidly increasing populations and incomes. Climate change will affect the spatial and temporal distribution of run-off, and thus affect availability from the supply side. The combined effect of these factors can be dramatic in particular hotspots, which include northern Africa, India, China, parts of Europe, the western US and eastern Australia, among others

    The pipeline project: Pre-publication independent replications of a single laboratory's research pipeline

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    This crowdsourced project introduces a collaborative approach to improving the reproducibility of scientific research, in which findings are replicated in qualified independent laboratories before (rather than after) they are published. Our goal is to establish a non-adversarial replication process with highly informative final results. To illustrate the Pre-Publication Independent Replication (PPIR) approach, 25 research groups conducted replications of all ten moral judgment effects which the last author and his collaborators had “in the pipeline” as of August 2014. Six findings replicated according to all replication criteria, one finding replicated but with a significantly smaller effect size than the original, one finding replicated consistently in the original culture but not outside of it, and two findings failed to find support. In total, 40% of the original findings failed at least one major replication criterion. Potential ways to implement and incentivize pre-publication independent replication on a large scale are discussed

    The “I” in us, or the eye on us? Regulatory focus, commitment and derogation of an attractive alternative person

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    When individuals are highly committed to their romantic relationship, they are more likely to engage in pro-relationship maintenance mechanisms. The present research expanded on the notion that commitment redirects self-oriented goals to consider broader relational goals and examined whether commitment interacts with a promotion and prevention focus to activate derogation of attractive alternatives. Three studies used cross-sectional and experimental approaches. Study 1 showed that romantically involved individuals predominantly focused on promotion, but not prevention, reported less initial attraction to an attractive target than single individuals, especially when highly committed to their relationship. Study 2 showed that romantically involved individuals induced in a promotion focus, compared to those in prevention focus, reported less initial attraction, but only when more committed to their relationship. Regardless of regulatory focus manipulation, more committed individuals were also less likely to perceive quality among alternative scenarios and to be attentive to alternative others in general. Finally, Study 3 showed that romantically involved individuals induced in promotion focus and primed with high commitment reported less initial attraction, than those primed with low commitment, or than those induced in prevention focus. Once again, for these latter no differences occurred according to commitment prime. Together, the findings suggest that highly committed promotion focused individuals consider broader relationship goals and activate relationship maintenance behaviors such as derogation of attractive alternatives to promote their relationship
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