Distributed Resources Shift Paradigms on Power System Design, Planning, and Operation: An Application of the GAP Model

Power systems have evolved following a century-old paradigm of planning and operating a grid based on large central generation plants connected to load centers through a transmission grid and distribution lines with radial flows. This paradigm is being challenged by the development and diffusion of modular generation and storage technologies. We use a novel approach to assess the sequencing and pacing of centralized, distributed, and off-grid electrification strategies by developing and employing the grid and access planning (GAP) model. GAP is a capacity expansion model to jointly assess operation and investment in utility-scale generation, transmission, distribution, and demand-side resources. This paper conceptually studies the investment and operation decisions for a power system with and without distributed resources. Contrary to the current practice, we find hybrid systems that pair grid connections with distributed energy resources (DERs) are the preferred mode of electricity supply for greenfield expansion under conservative reductions in photovoltaic panel (PV) and energy storage prices. We also find that when distributed PV and storage are employed in power system expansion, there are savings of 15%-20% mostly in capital deferment and reduced diesel use. Results show that enhanced financing mechanisms for DER PV and storage could enable 50%-60% of additional deployment and save 15 /MWh in system costs. These results have important implications to reform current utility business models in developed power systems and to guide the development of electrification strategies in underdeveloped grids

Solution and Asymptotic Behavior for a Nonlocal Coupled System of Reaction-Diffusion

This paper concerns with existence, uniqueness and asymptotic behavior of the solutions for a nonlocal coupled system of reaction-diffusion. We prove the existence and uniqueness of weak solutions by the Faedo-Galerkin method and exponential decay of solutions by the classic energy method. We improve the results obtained by Chipot-Lovato and Menezes for coupled systems. A numerical scheme is presented

Encephalic xanthomas in a large malayan chevrotain (Tragulus napu)

An adult water chevrotain was euthanized due to severe non-responsive pododermatitis. Incidentally, multiple to coalescing cholesterol granulomas were identified within the right diencephalon, characterized by the presence of foamy macrophagesand cholesterol clefts consistent with encephalic xanthomas. No clinical signs or predisposing conditions associated with this findingwere identified. This is the first known report of encephalic xanthomas in this species

Impact of Wind, Solar, and Other Factors on Wholesale Power Prices: An Historical Analysis—2008 through 2017

Wholesale power markets have evolved. Some of the most prominent changes over the last decade in the United States include growth in wind and solar, a reduction in the price of natural gas, weakened load growth, and an increase in the retirement of thermal power plants. Here we empirically assess the degree to which wind and solar—among other factors—have influenced wholesale electricity prices. We show that wind and solar have contributed to reductions in overall average annual wholesale electricity prices since 2008, but that natural gas prices have had the largest impact. More notable is that expansion of variable renewable energy has led to significant changes in locational, time of day, and seasonal pricing patterns in some regions. These altered pricing patterns reflect a fundamental shift, and hold important implications for the grid-system value of wind and solar, and for other electric-sector planning and operating decisions

Monitoring biological wastewater treatment processes: Recent advances in spectroscopy applications

Biological processes based on aerobic and anaerobic technologies have been continuously developed to wastewater treatment and are currently routinely employed to reduce the contaminants discharge levels in the environment. However, most methodologies commonly applied for monitoring key parameters are labor intensive, time-consuming and just provide a snapshot of the process. Thus, spectroscopy applications in biological processes are, nowadays, considered a rapid and effective alternative technology for real-time monitoring though still lacking implementation in full-scale plants. In this review, the application of spectroscopic techniques to aerobic and anaerobic systems is addressed focusing on UV--Vis, infrared, and fluorescence spectroscopy. Furthermore, chemometric techniques, valuable tools to extract the relevant data, are also referred. To that effect, a detailed analysis is performed for aerobic and anaerobic systems to summarize the findings that have been obtained since 2000. Future prospects for the application of spectroscopic techniques in biological wastewater treatment processes are further discussed.The authors thank the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit, COMPETE 2020 (POCI-01-0145-FEDER-006684) and the project RECI/BBB-EBI/0179/2012 (FCOMP-01-0124-FEDER-027462) and BioTecNorte operation (NORTE-01-0145-FEDER-000004) funded by the European Regional Development Fund under the scope of Norte2020 - Programa Operacional Regional do Norte. The authors also acknowledge the financial support to Daniela P. Mesquita and Cristina Quintelas through the postdoctoral Grants (SFRH/BPD/82558/2011 and SFRH/BPD/101338/2014) provided by FCT - Portugal.info:eu-repo/semantics/publishedVersio

Venezuela, April 2002: Coup or Popular Rebellion? The Myth of a United Venezuela

This article assesses the merits of opposing National Assembly reports into the coup against President Chavez of Venezuela in April 2002. Looking at the historical context and the content of the reports, it argues that the two opposing accounts reflect a class division that has always existed in Venezuela but has been officially denied. It concludes that a possible exit from the stalemate could be that the opposition accept the reality of this class division and therefore the Chavez government as a legitimate representative of the popular classes. This, however, is unlikely in the present circumstances

Characteristics and impact of interventions to support healthcare providers’ compliance with guideline recommendations for breast cancer: a systematic literature review

BackgroundBreast cancer clinical practice guidelines (CPGs) offer evidence-based recommendations to improve quality of healthcare for patients. Suboptimal compliance with breast cancer guideline recommendations remains frequent, and has been associated with a decreased survival. The aim of this systematic review was to characterize and determine the impact of available interventions to support healthcare providers' compliance with CPGs recommendations in breast cancer healthcare.MethodsWe searched for systematic reviews and primary studies in PubMed and Embase (from inception to May 2021). We included experimental and observational studies reporting on the use of interventions to support compliance with breast cancer CPGs. Eligibility assessment, data extraction and critical appraisal was conducted by one reviewer, and cross-checked by a second reviewer. Using the same approach, we synthesized the characteristics and the effects of the interventions by type of intervention (according to the EPOC taxonomy), and applied the GRADE framework to assess the certainty of evidence.ResultsWe identified 35 primary studies reporting on 24 different interventions. Most frequently described interventions consisted in computerized decision support systems (12 studies); educational interventions (seven), audit and feedback (two), and multifaceted interventions (nine). There is low quality evidence that educational interventions targeted to healthcare professionals may improve compliance with recommendations concerning breast cancer screening, diagnosis and treatment. There is moderate quality evidence that reminder systems for healthcare professionals improve compliance with recommendations concerning breast cancer screening. There is low quality evidence that multifaceted interventions may improve compliance with recommendations concerning breast cancer screening. The effectiveness of the remaining types of interventions identified have not been evaluated with appropriate study designs for such purpose. There is very limited data on the costs of implementing these interventions.ConclusionsDifferent types of interventions to support compliance with breast cancer CPGs recommendations are available, and most of them show positive effects. More robust trials are needed to strengthen the available evidence base concerning their efficacy. Gathering data on the costs of implementing the proposed interventions is needed to inform decisions about their widespread implementation

Regional variability in diving physiology and behavior in a widely distributed air-breathing marine predator, the South American sea lion (Otaria byronia)

Our understanding of how air-breathing marine predators cope with environmental variability is limited by our inadequate knowledge of their ecological and physiological parameters. Because of their wide distribution along both coasts of the sub-continent, South American sea lions (Otaria byronia) provide a valuable opportunity to study the behavioral and physiological plasticity of a marine predator in different environments.We measured the oxygen stores and diving behavior of South American sea lions throughout most of its range, allowing us to demonstrate that diving ability and behavior vary across its range.We found no significant differences in mass-specific blood volumes of sea lions among field sites and a negative relationship between massspecific oxygen storage and size, which suggests that exposure to different habitats and geographical locations better explains oxygen storage capacities and diving capability in South American sea lions than body size alone. The largest animals in our study (individuals from Uruguay) were the shallowest and shortest duration divers, and had the lowest mass-specific total body oxygen stores, while the deepest and longest duration divers (individuals from southern Chile) had significantly larger mass-specific oxygen stores, despite being much smaller animals. Our study suggests that the physiology of airbreathing diving predators is not fixed, but that it can be adjusted, to a certain extent, depending on the ecological setting and or habitat. These adjustments can be thought of as a 'training effect': as the animal continues to push its physiological capacity through greater hypoxic exposure, its breath-holding capacity increases

Parainfluenza virus infection associated with posterior reversible encephalopathy syndrome: a case report

<p>Abstract</p> <p>Introduction</p> <p>Posterior reversible encephalopathy syndrome is a clinical and radiological entity. The most accepted theory of posterior reversible encephalopathy syndrome is a loss of autoregulation in cerebral blood flow with a subsequent increase in vascular permeability and leakage of blood plasma and erythrocytes, producing vasogenic edema. In infection-associated posterior reversible encephalopathy syndrome, a clinical pattern consistent with systemic inflammatory response syndrome develops. Parainfluenza virus has not been reported in the medical literature to be associated with posterior reversible encephalopathy syndrome.</p> <p>Case presentation</p> <p>We report herein the case of a 54-year-old Caucasian woman with posterior reversible encephalopathy syndrome associated with parainfluenza virus infection who presented with generalized headache, blurring of vision, new-onset seizure and flu-like symptoms.</p> <p>Conclusion</p> <p>Infection-associated posterior reversible encephalopathy syndrome as well as hypertension-associated posterior reversible encephalopathy syndrome favor the contribution of endothelial dysfunction to the pathophysiology of this clinicoradiological syndrome. In view of the reversible nature of this clinical entity, it is important that all physicians are well aware of posterior reversible encephalopathy syndrome in patients presenting with headache and seizure activity. A detailed clinical assessment leading to the recognition of precipitant factors in posterior reversible encephalopathy syndrome is paramount.</p