In vivo accumulation of biofunctionalized AgNPs using Spirulina

The scientific results were obtained within the project 20.80009.5007.05 „Biofunctionalized metal nanoparticles – obtaining using cyanobacteria and microalgae” funded by NARD, Republic of Moldova.The 4.7 nm polyethylene glycol-stabilized AgNPs were functionalized with spirulina culture during a cultivation cycle. Experiments with laboratory animals were carried out at the Institute of Physiology and Sanocreatology, the Laboratory of Physiology of Stress, Adaptation and General Sanocreatology, and in the Institute’s vivarium. AgNPs were administered to animals of the experimental group at a dose of 1 μg Ag/day/animal. Laboratory animals were divided into several groups: two control groups: rats normally kept without food additives and rats fed with spirulina biomass; and two experimental groups: rats treated with silver nanoparticles and an animal group treated with functionalized silver nanoparticles using spirulina. The experience included an administration period of 28 days followed and a 28 days clearance period. It has been established that AgNPs functionalized with spirulina acquire new biological properties, different from those of non-functionalized AgNPs, and consequently new areas of application

Metal removal from erbium-containing wastewater using Arthospira platensis

Cyanobacteria Arthospira platensis was used for Er(III) removal from wastewater by applying biosorption and bioaccumulation processes. The optimal conditions for Er(III) removal were defined as pH 3.0, time 15 min and temperature 20 ◦C, when 30 mg/g of Er(III) were removed

Sulfated polysaccharides as agents for free radicals annihilation in spirulina biomass cultivated under the induced illumination stress conditions

Spirulina platensis is the source of sulfated polysaccharides known as Na (Ca) spirulan with antiviral and anti-inflammatory action. In the cell sulfated polysaccharides as polyanionic complexes located on the external membrane surface, perform intercellular connections playing the role of tissue barriers, cell adhesion, protection against pathogens and serve as well as reservoir of growth factors. It was demonstrated the involvement of sulfated polysaccharides in the annihilation of hydroxyl radicals and peroxide formed as a result of the Fenton reaction, and indirectly in the lipid protection against oxidation

Procedures for obtaining cyanobacterial and microalgal biomass – source of multifunctional remedies

Patents No.: MD 130Y; MD 4542; MD 4543; MD Patent application No. 4598Field of study: Medicine and human factors. Pharmacy and cosmetics. Food bio – securityThe procedures refer to biotechnology and bionanotechnology in particular to processes for biomass production and cultivation of cyanobacterium Spirulina platensis and microalga Dunaliella salina - sources of multifunctional remedies

Le syndrome métabolique chez les patients souffrant de goutte

29e Congrès Français de Rhumatologie - Porte de Versailles, Paris, 11-13 Décembre 201

Le syndrome métabolique chez les patients souffrant de goutte

29e Congrès Français de Rhumatologie - Porte de Versailles, Paris, 11-13 Décembre 201

Red Algae <I>Porphyridium cruentum</I> Growth Stimulated by CdSe Quantum Dots Covered with Thioglycerol

Acces full text - https://doi.org/10.1166/jno.2012.1416CdSe nanoparticles were synthesized using colloidal methods. In order to obtain hydric colloidal solution, the surface of the quantum dots has been modified with thioglycerol. The presence of thioglycerol on the CdSe quantum dots was confirmed by infrared spectroscopy. The hydric solution of CdSe was used in biological tests. The red algae Porphyridium cruentum was investigated as biological object. Quantum dots were added in the microalgae cultivation medium in a quantity of 1–10 mg/l. Quantities of 4–8 mg/l have shown a stimulating effect, i.e., increasing the amount of accumulated biomass to 18, 2–47% in comparison with the control sample. The absence of toxic effects of CdSe quantum dots was indicated by the determination test of the malonic dialdehyde that manifested the lack of membrane lipoprotein oxidation. A new area of application of CdSe nanoparticles was defined, namely that of phycobiotechnology

Определение корреляционной зависимости между значениями теста ABTS и содержанием каротиноидов в этанольных экстрактах из биомассы зеленой водоросли Haematococcus pluvialis

A fost determinată existența unei corelări foarte puternice R2=0,9 dintre conținutul de carotenoizi și valorile testului ABTS în extractele etanolice, obținute în baza biomasei de Haematococcus pluvialis, colectată în faza celulelor verzi mobile și ciști roșii. Acest tip de corelare este caracteristic carotenului din complexul antioxidant extras din biomasa algală verde și astaxantinei, obținută din ciștii roșii. Dependența dată se respectă și în cazul modulării activității biosintetice la Haematococcus prin aplicarea compușilor coordinativi ai cobaltului cu bazele Schiff.There is a strong correlation (R2 = 0.9) between the carotenoid content and the ABTS test values in the ethanol extracts from Haematococcus pluvialis biomass collected during the green cell phase and red cysts. This type of correlation is characteristic of the carotene contained in the antioxidant complex extracted from green algal biomass and of the astaxanthin produced from red cysts. A strong correlation relationship was also observed in the experiments on the cellular biosynthetic activity modulation in Haematococcus pluvialis by application of Schiff base coordination cobalt complexes.Было установлено наличие сильной корреляционной зависимости (R2=0,9) между содержанием каротиноидов и значениями теста ABTS в этанольных экстрактах, полученных из биомассы зеленой водоросли Haematococcus pluvialis, собранной на этапе мобильных зеленых клеток и на этапе красных апланоспор. Такой тип корреляционной зависимости характерен для каротина, содержащегося в составе антиоксидантного комплекса, полученного из биомассы зеленых клеток и для астаксантина, полученного из красных апланоспор. Корреляционная зависимость наблюдается также и в случае применения воздействия на культуру Haematococcus pluvialis в целях изменения ее биосинтетической активности путем применения координационных соединений кобальта с Шиффовыми основаниями