Sistem Pendukung Keputusan Penerimaan Pegawai Baru PT.PLN (Persero) Kantor Pusat dengan Menggunakan Metode Simple Additive Weighting (SAW)

PT PLN (Persero) is the largest state owned companies in Indonesia that handle electricity services throughout Indonesia and is headquartered in Jakarta. To support the progressive growth and build the organizational capability, PT PLN (Persero) in serving the community needed human resources berkualitas.Dalam it is necessary to build a decision support system to assist in the selection and set-based employee PT.PLN (Persero). Wrong a model that can be used for decision support system is a model of Multiple Attribute Decision Making (MADM) with Simple Additive weighting method (SAW). This method was chosen because this method determines the weight values for each attribute, followed by a ranking process that will select the best alternative. Research carried out by finding the weights for each criterion, and then make the ranking process that will determine the optimal alternative is the best applicants. Results of the application decision support system is the best alternative to the election of the applicant is entitled to be an employee because of pass selection in sequence according to the ranking using the programming language PHP

Atypical presentation of neuronal ceroid lipofuscinosis type 8 in a sibling pair and review of the eye findings and neurological features.

Purpose:To report atypical presentation of neuronal ceroid lipofuscinoses type 8 (CLN8) to the eye clinic and review clinical features of CLN8. Observations:Detailed eye exam by slit lamp exam, indirect ophthalmoscopy, fundus photography, optical coherence tomography, visual fields and electroretinogram (ERG). Molecular genetic testing using Next Generation Sequencing panel (NGS) and array Comparative Genomic Hybridization (aCGH).The siblings in this study presented to the eye clinic with retinitis pigmentosa and cystoid macular edema, and a history of seizures but no severe neurocognitive deficits or regression. Genetic testing identified a c.200C > T (p.A67V) variant in the CLN8 gene and a deletion encompassing the entire gene. Electron microscopy of lymphocytes revealed fingerprint inclusions in both siblings. Conclusions:and Importance: Pathogenic variants in CLN8 account for the retinitis pigmentosa and seizures in our patients however, currently, they do not have regression or neurocognitive decline. The presentation of NCL can be very diverse and it is important for ophthalmologists to consider this in the differential diagnosis of retinal disorders with seizures or other neurological features. Molecular genetic testing of multiple genes causing isolated and syndromic eye disorders using NGS panels and aCGH along with additional complementary testing may often be required to arrive at a definitive diagnosis

Pengaruh Motivasi Internal dan Eksternal terhadap Kinerja Karyawan (Studi Kasus pada Karyawan PT Indomarco Prismatama Distribution Centre Bogor)

This research is to analyze the influence of simultaneously Internal Motivation and External Motivation on Employee Performance and analyze the influence of parisal Internal Motivation on Employee Performance and Partial Influence of External Motivation to Employee Performance PT Indomarco Prismatama Distribution Center Bogor. Sample collection in this study using simple random sampling technique conducted on 91 respondents from 892 employees. Data analysis technique used is multiple linear regression analysis that serves to prove the research hypothesis. The data that have met the validity test, reliability test, and classical assumption test are processed so as to produce regression equation Y = 0,284 X1 + 0,269 X2. From this research indicate that based on the test by using multiple linear regression model t test and F test, internal motivation and external motivation simultaneously influence simultaneously significant to employee performance with Fhitung еquаl to 9,912 аnd Ftаbеl 3,10. Pаrtiаlly, it wаs found thаt intеrnаl motivаtion vаriаblе significаntly influеncе еmployее pеrformаncе with vаriаblе rеgrеssion coеfficiеnt vаluе of 0.284. Kеywords: Intеrnаl Motivаtion, Еxtеrnаl Motivаtion, Еmployее Pеrformаncе. АBSTRАK Pеnеlitiаn ini untuk mеngаnаlisis pеngаruh sеcаrа simultаn Motivаsi Intеrnаl dаn Motivаsi Еkstеrnаl tеrhаdаp Kinеrjа Kаryаwаn dаn mеngаnаlisis pеngаruh pаrisаl Motivаsi Intеrnаl tеrhаdаp Kinеrjа Kаryаwаn sеrtа pеngаruh pаrsiаl Motivаsi Еkstеrnаl tеrhаdаp Kinеrjа Kаryаwаn PT Indomаrco Prismаtаmа Distribution Cеntrе Bogor. Pеngumpulаn sаmpеl dаlаm pеnеlitiаn ini mеnggunаkаn tеknik simplе rаndom sаmpling yаng dilаkukаn tеrhаdаp 91 orаng rеspondеn dаri 892 kаryаwаn. Tеknik аnаlisis dаtа yаng digunаkаn аdаlаh аnаlisis liniеr rеgrеsi bеrgаndа yаng bеrfungsi untuk mеmbuktikаn hipotеsis pеnеlitiаn. Dаtа-dаtа yаng tеlаh mеmеnuhi uji vаliditаs, uji rеliаbilitаs, dаn uji аsumsi klаsik diolаh sеhinggа mеnghаsilkаn pеrsаmааn rеgrеsi Y = 0,284 X1 + 0,269 X2. Dаri pеnеlitiаn ini mеnunjukkаn bаhwа bеrdаsаrkаn pеngujiаn dеngаn mеnggunаkаn modеl rеgrеsi liniеr bеrgаndа uji t dаn uji F, motivаsi intеrnаl dаn motivаsi еkstеrnаl sеcаrа bеrsаmа-sаmа bеrpеngаruh sеcаrа simultаn signifikаn tеrhаdаp kinеrjа kаryаwаn dеngаn Fhitung sеbеsаr 9,912 dаn Ftаbеl 3,10. Sеcаrа pаrsiаl, ditеmukаn bаhwа vаriаbеl motivаsi intеrnаl bеrpеngаruh sеcаrа signifikаn tеrhаdаp kinеrjа kаryаwаn dеngаn nilаi koеfisiеn rеgrеsi vаriаbеl sеbеsаr 0,284. Kаtа Kunci: Motivаsi Intеrnаl, Motivаsi Еkstеrnаl, Kinеrjа Kаryаwаn

Pengaruh Komposisi Semen Dan Agregat Kasar Batu Apung Terhadap Kuat Lentur Balok Beton Bertulang Bambu Dengan Campuran Serat Bambu

Perkembangan Ilmu dalam bidang Kontruksi pada masa sekarang di Indonesia begitu pesat .salah satu teknologi beton yang berkembang dalam USAha pembuatan rumah tahan gempa adalah penggunaan beton ringan.Mengingat bahwa Sumber daya Alam yang sudah mulai susah di daur ulang mulai dikembangkan tulangan pengganti baja dengan menggunakan Bambu sebagai tulangan ,adapun pemanfaatan limbah bambu seperti penggunaan Serat bambu sebagai filler pada beton.Tugas akhir ini membahas mengenai Pengaruh Komposisi Semen dan Agregat kasar Batu Apung Terhadap Kuat Lentur Balok Beton Bertulang Bambu dengan Campuran Serat Bambu. Dalam penelitian ini elemen yang digunakan adalah balok berukuran 20 cm x 15 cm x 160 cm .Penentuan komposisi semen dan agregat pada penelitian ini menjadi pembahasan dalam pengujian balok.Penelitian ini menggunakan metode eksperimen dengan total 12 benda uji dengan 4 rancangan benda uji. Benda uji dibuat berdasarkan perhitungan sampel dengan percobaan faktorial sebagian.masing masing benda uji yaitu serat bambu 40 gram komposisi semen agregat 1:2:1 rasio tulangan 1% , serat bambu 40 gram komposisi semen dan agregat 1:2,5:1,5 rasio tulangan 1,5%, serat bambu 150 gram komposisi semen dan agregat 1:2:1 rasio tulangan 1,5% dan serat bambu 150 gram komposisi semen dan agregat 1:2,5:1,5 rasio tulangan 1% .Hasil pengujian menunjukan bahwa kekakuan komposisi tinggi 1:2:1 lebih kaku dan kuat menahan beban sehingga lendutan yang didapatkan lebih kecil dibandingkan dengan komposisi 1:2,5:1,5.Namun pada penelitian ini mengalami perbedaan antara uji coba dengan teori yang ada . Salah satu penyebabnya adalah ketidak kompak nya antara bambu dan beton, sehingga daya lekat bambu terhadap beton kurang.Pada perhitungan statistik uji anova satu arah diketahui bahwa belum ada pengaruh komposisi semen dan agregat pada beton bertulang bambu dengan serat

Pengaruh Campuran Kadar Bottom Ash Dan Lama Perendaman Air Laut Terhadap Pola, Lebar Dan Kedalaman Retak Pada Balok

Dari pengujian ini didapatkan bahwa terdapat pengaruh variasi campuran bottom ash dimana nilai kuat tekan yang paling tinggi terjadi pada campuran bottom ash 10%. Demikian juga halnya dengan hasil pengamatan pola retak, dimana hingga terjadi kegagalan geser pada balok uji dengan keruntuhan geser. Hal ini terjadi pada balok beton dengan keruntuhan geser perendaman 28 hari campuran bottom ash 10%. Perbedaan kemunculan retak awal pada benda uji dengan keruntuhan geser perendaman 14 hari menunjukkan pengaruh variasi kadar campuran bottom ash terhadap lebar retak. Berikut juga dengan besar nilai lebar retak maksimum pada balok dengan keruntuhan lentur durasi perendaman 28 hari yang dianalisis oleh peneliti. Yaitu, 0,16 mm pada campuran bottom ash 0%; 0,10 mm pada campuran bottom ash 10%; 0,12 mm pada campuran bottom ash 20% dan sebesar 0,13 mm pada campuran bottom ash 25%. Variasi durasi perendaman air laut juga memberikan pengaruh yang cukup signifikan. Seperti pada keruntuhan lentur perendaman 14 hari yaitu dengan lebar retak 0,10 mm untuk campuran bottom ash 0%; 0,13 mm untuk campuran bottom ash 10%; 0,14 mm untuk campuran bottom ash 20% dan 0,12 mm untuk campuran bottom ash 25%. Dengan lebar retak maksimum yang diijinkan oleh ACI Code untuk daerah basah khususnya dalam lingkup air laut adalah 0.15 mm dan sering dibulatkan menjadi 0.20 mm, sehingga hasil penelitian ini masih bisa digunakan sebagai acuan untuk penelitian selanjutnya. Keterbatasan alat uji menjadi masalah utama dalam pengukuran kedalaman retak. Hal ini menyebabkan tidak dapat dihimpunnya data dengan baik

Implementasi Kabijakan Pembangunan Infrastruktur Jalan dalam Mendukung Pengembangan Ekonomi Masyarakat di Kabupaten Sorong Propinsi Papua Barat

Implementation of Road Infrastructure Development Policy in Support of Community EconomicDevelopment in Sorong. This study aims to find out about the Road Infrastructure Development inSupport of Economic Development conducted by the government of Sorong in particular Umum.OlehWorks Department for the government\u27s role in encouraging the development area should be donewith a set of policies and actions that can improve regional economy Sorong.This study was conducted in Sorong, the process of data collection is done by observation, interviewand documentation. Informants in this study consisted of 14 people. The data collected later describedby using qualitative methods.Results from this study indicate that the construction of road infrastructure in Sorong Regency is goodenough, but not fully wishes of the people can be responded to by the government, especially theDepartment of Public Works. Thus the author can propose to the government to the natural resourcesthat could be used for the benefit of local communities in Sorong for the present and the future

Platelets Recognize Brain-Specific Glycolipid Structures, Respond to Neurovascular Damage and Promote Neuroinflammation

Platelets respond to vascular damage and contribute to inflammation, but their role in the neurodegenerative diseases is unknown. We found that the systemic administration of brain lipid rafts induced a massive platelet activation and degranulation resulting in a life-threatening anaphylactic-like response in mice. Platelets were engaged by the sialated glycosphingolipids (gangliosides) integrated in the rigid structures of astroglial and neuronal lipid rafts. The brain-abundant gangliosides GT1b and GQ1b were specifically recognized by the platelets and this recognition involved multiple receptors with P-selectin (CD62P) playing the central role. During the neuroinflammation, platelets accumulated in the central nervous system parenchyma, acquired an activated phenotype and secreted proinflammatory factors, thereby triggering immune response cascades. This study determines a new role of platelets which directly recognize a neuronal damage and communicate with the cells of the immune system in the pathogenesis of neurodegenerative diseases

Defleksi Balok Melintang Dan Tegangan Batang Diagonal Tepi Jembatan “Boomerang Bridge” Akibat Variasi Posisi Pembebanan

Jembatan Boomerang sendiri merupakan jembatan rangka dengan konfigurasi rangka jenis K-truss. Dalam perhitungan secara teoritis dan Kenyataan lendutan yang dihasilkan sangat berbeda, Perbedaan angka lendutan secara teoritis dengan pengujian lapangan inilah yang menjadi dasar dari penelitian ini. Dengan meninjau lendutan balok melintang dan tegangan batang diagonal rangka tepi nantinya akan dapat dilihat pengaruh perletakkan beban yang diberikan. Pada penelitian ini dilakukan pengujian serta perhitungan teoritis sebagai perbandingan. Pengujian dilakukan dengan memberikan beban garis dengan menggunakan balok pemerata atas beban terpusat 400 Kg. Beban diletakkan pada poisisi 1 (1/4 bentang kiri jembatan), posisi 2 (1/2 bentang jembatan) dan posisi 3 (1/4 bentang kanan jembatan). Pengujian untuk memperoleh besar tegangan dilakukan dengan menggunakan strain gauge, sedangkan untuk lendutan digunakan LVDT. Sedangkan untuk perhitungan teoritis digunakan program. Pengujian elastisitas bahan juga dilakukan untuk ketelitian hasil pengujian dan perhitungan. Hasil pengujian dan perhitungan teoritis sama-sama menyatakan bahwa posisi beban sangat berpengaruh terhadap tegangan batang diagonal tepi juga lendutan balok melintang yang terjadi. Selain itu didapatkan hasil yang cukup berbeda jauh antara pengujian dengan perhitungan teoritis

Validation as New Imaging Biomarker

Background In order to select patients most likely to benefit for thrombolysis and to predict patient outcome in acute ischemic stroke, the volumetric assessment of the infarcted tissue is used. However, infarct volume estimation on Diffusion weighted imaging (DWI) has moderate interrater variability despite the excellent contrast between ischemic lesion and healthy tissue. In this study, we compared volumetric measurements of DWI hyperintensity to a simple maximum orthogonal diameter approach to identify thresholds indicating infarct size >70 ml and >100 ml. Methods Patients presenting with ischemic stroke with an NIHSS of ≥ 8 were examined with stroke MRI within 24 h after symptom onset. For assessment of the orthogonal DWI lesion diameters (od- values) the image with the largest lesion appearance was chosen. The maximal diameter of the lesion was determined and a second diameter was measured perpendicular. Both diameters were multiplied. Od-values were compared to volumetric measurement and od-value thresholds identifying a lesion size of > 70 ml and > 100 ml were determined. In a selected dataset with an even distribution of lesion sizes we compared the results of the od value thresholds with results of the ABC/2 and estimations of lesion volumes made by two resident physicians. Results For 108 included patients (53 female, mean age 71.36 years) with a median infarct volume of 13.4 ml we found an excellent correlation between volumetric measures and od-values (r2 = 0.951). Infarct volume >100 ml corresponds to an od-value cut off of 42; > 70 ml corresponds to an od-value of 32. In the compiled dataset (n = 50) od-value thresholds identified infarcts > 100 ml / > 70 ml with a sensitivity of 90%/ 93% and with a specificity of 98%/ 89%. The od-value offered a higher accuracy in identifying large infarctions compared to both visual estimations and the ABC/2 method. Conclusion The simple od-value enables identification of large DWI lesions in acute stroke. The cutoff of 42 is useful to identify large infarctions with volume larger than 100 ml. Further studies can analyze the therapeutic utility of this new method