771 research outputs found
PeP-SCOT a health coaching intervention for people in prisons:the development of the intervention protocol
The need for an alternative approach for health promotion interventions in the prison setting is required since previous work has indicated that health education interventions while improving health knowledge do not result in behaviour change. Evidence has suggested that a health coaching intervention assist in this regard, however, the question remained whether this approach would be appropriate and possible in the prison setting. This Dental Public Health in Action paper presents the public health strategies used to work in partnership with prison management, to address challenges and accept opportunities as we developed a health coaching intervention protocol for oral health and wellbeing in the prison setting
Amyloid Inspired Self-Assembled Peptide Nanofibers
Cataloged from PDF version of article.Amyloid peptides are important components in many degenerative
diseases as well as in maintaining cellular metabolism. Their unique stable structure
provides new insights in developing new materials. Designing bioinspired selfassembling
peptides is essential to generate new forms of hierarchical nanostructures.
Here we present oppositely charged amyloid inspired peptides (AIPs),
which rapidly self-assemble into nanofibers at pH 7 upon mixing in water caused
by noncovalent interactions. Mechanical properties of the gels formed by selfassembled
AIP nanofibers were analyzed with oscillatory rheology. AIP gels
exhibited strong mechanical characteristics superior to gels formed by self-assembly
of previously reported synthetic short peptides. Rheological studies of gels
composed of oppositely charged mixed AIP molecules (AIP-1 + 2) revealed superior mechanical stability compared to individual
peptide networks (AIP-1 and AIP-2) formed by neutralization of net charges through pH change. Adhesion and elasticity
properties of AIP mixed nanofibers and charge neutralized AIP-1, AIP-2 nanofibers were analyzed by high resolution force−
distance mapping using atomic force microscopy (AFM). Nanomechanical characterization of self-assembled AIP-1 + 2, AIP-1,
and AIP-2 nanofibers also confirmed macroscopic rheology results, and mechanical stability of AIP mixed nanofibers was higher
compared to individual AIP-1 and AIP-2 nanofibers self-assembled at acidic and basic pH, respectively. Experimental results were
supported with molecular dynamics simulations by considering potential noncovalent interactions between the amino acid
residues and possible aggregate forms. In addition, HUVEC cells were cultured on AIP mixed nanofibers at pH 7 and biocompatibility
and collagen mimetic scaffold properties of the nanofibrous system were observed. Encapsulation of a zwitterionic
dye (rhodamine B) within AIP nanofiber network was accomplished at physiological conditions to demonstrate that this network
can be utilized for inclusion of soluble factors as a scaffold for cell culture studies. Copyright © 2012 American Chemical Societ
Label-Free Nanometer-Resolution Imaging of Biological Architectures through Surface Enhanced Raman Scattering
Label free imaging of the chemical environment of biological specimens would readily bridge the supramolecular and the cellular scales, if a chemical fingerprint technique such as Raman scattering can be coupled with super resolution imaging. We demonst
The impact of point mutations in the human androgen receptor : classification of mutations on the basis of transcriptional activity
Peer reviewedPublisher PD
The effect of consumer emotions on online purchasing behavior
This chapter was written to demonstrate the effect of consumer emotion on online purchasing behavior. According to the results obtained from 418 data, it was observed that both positive and negative emotions impacted online buying behavior. In this context, as the positive emotions of the online consumer increases, the frequency of purchases increases, but as the negative emotions of the online consumer increases, the frequency of purchases decreases. In addition, user interface quality, product information quality, service information quality, site awareness, security perception, information satisfaction, and relational benefit factors are factors that negatively affect consumers emotionally in purchasing online. On the other hand, only product information quality, user interface quality, and security perception factors positively affect emotions of online consumers. © 2020, IGI Global
Stress Distribution in an Infinite Body Containing Two Neighboring Locally Curved Nanofibers
In the present paper, the stress distribution in an infinite elastic body containing two neighboring nanofibers is studied. It is assumed that the midlines of the fibers are in the same plane. With respect to the location of the fibers according to each other the co-phase and anti-phase curving cases are considered. At infinity uniformly distributed normal forces act in the direction of the nanofibers, location. The investigations are carried out in the framework of the piecewise homogeneous body model with the use of the three-dimensional geometrically non-linear exact equations of the theory of elasticity. The normal and shear self-equilibrated stresses arising as a result of the nanofiber curving are analyzed. In particular, the influence of the interaction between the fibers on the distribution of these stresses is studied. A lot of numerical results on the effect of the geometrical non-linearity to the values of the self balanced shear and normal stresses are presented
Is London open? Mediating and ordering cosmopolitanism in crisis
This article analyses cosmopolitan imagination and ambivalent morality at times of urban crisis. It focuses on #LondonIsOpen – the city’s media campaign in response to the nation’s Brexit vote. In this case, cosmopolitanism’s discursive tools – especially the ideals of the Open city and hospitality – are mobilised to summon a range of actors in defence of the city. The article analyses the mediation of cosmopolitanism in a campaign film and in Londoners’ online and offline responses to it. These responses reveal #LondonIsOpen as a compelling example of cosmopolitan imagination, but also of cosmopolitanism’s moral fragility in the neoliberal city. As shown, urban dwellers overwhelmingly embrace the cosmopolitan value of openness. Yet, their visions are divided between neoliberal cosmopolitanism and vernacular cosmopolitanism. By analysing the moral space of mediated cosmopolitanism, I argue that, unlike the nation, representational struggles in the city increasingly take place within, rather than against, cosmopolitanis
Digital advertising practices and its impacts on students: An application in the public and private universities in Turkey
The subject of this chapter is the universities listed on the website of the Council of Higher Educationin Turkey. This study aims to reveal the importance of digital advertising in these universities. In thisstudy, firstly, the websites of these universities were examined. Secondly, the social networking andmobile applications listed in these websites were examined. The results of the current study states thoseTurkish universities' efforts are inadequate. This is clearly seen in mobile application and video sharingtendencies. Although most of them use social networking websites, the contents of their profiles are notattractive enough to draw the attention of young people. Therefore, special interest has to be given tocontent management on social networking profiles. © 2017, IGI Global. All rights reserved
J-Integral Calculation by Finite Element Processing of Measured Full-Field Surface Displacements
© 2017 The Author(s)A novel method has been developed based on the conjoint use of digital image correlation to measure full field displacements and finite element simulations to extract the strain energy release rate of surface cracks. In this approach, a finite element model with imported full-field displacements measured by DIC is solved and the J-integral is calculated, without knowledge of the specimen geometry and applied loads. This can be done even in a specimen that develops crack tip plasticity, if the elastic and yield behaviour of the material are known. The application of the method is demonstrated in an analysis of a fatigue crack, introduced to an aluminium alloy compact tension specimen (Al 2024, T351 heat condition)
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