Vortices associated with the wave function of a single electron emitted in slow ion-atom collisions

We present measurements and calculations of the momentum distribution of electrons emitted during the ion-atom collision 10 keV/u $He^{2+}+He \rightarrow He^{+} + He^{2+} + e^{-}$, which show rich structures for ion scattering angles above 2 mrad arising dominantly from two-electron states. Our calculations reveal that minima in the measured distributions are zeros in the electronic probability density resulting from vortices in the electronic current

Brief history of serious games

Serious Games are now an established field of study. In this field most would attribute the rise of Serious Games to Clark C Abt’s creation of the term in 1970, or indeed Ben Sawyer’s popularization of it in 2002. However, considering the rich history of purposing non-digital games, itself preceded by discussions of purposing play that are traceable to the work of Plato, it can be said that Serious Games is a contemporary manifestation of centuries old theories and practices. In this chapter, we explore the pre-history of Serious Games, beginning with the suggested purpose, and purposing of play. Throughout this historical review we identify key in research and practice that are apparent in the contemporary Serious Games field

Broadening of hot-spot response spectrum of superconducting NbN nanowire single-photon detector with reduced nitrogen content

The spectral detection efficiency and the dark count rate of superconducting nanowire single-photon detectors (SNSPD) has been studied systematically on detectors made from thin NbN films with different chemical compositions. Reduction of the nitrogen content in the 4 nm thick NbN films results in a more than two orders of magnitude decrease of the dark count rates and in a red shift of the cut-off wavelength of the hot-spot SNSPD response. The observed phenomena are explained by an improvement of uniformity of NbN films that has been confirmed by a decrease of resistivity and an increase of the ratio of the measured critical current to the depairing current. The latter factor is considered as the most crucial for both the cut-off wavelength and the dark count rates of SNSPD. Based on our results we propose a set of criteria for material properties to optimize SNSPD in the infrared spectral region.Comment: 15 pages, 6 figure

Experimental Evidence for Selection Rules in Multiphoton Double Ionization of Helium

We report on the observation of phase space modulations in the correlated electron emission after strong field double ionization of helium using laser pulses with a wavelength of 394~nm and an intensity of $3\cdot10^{14}$W/cm$^2$. Those modulations are identified as direct results of quantum mechanical selection rules predicted by many theoretical calculations. They only occur for an odd number of absorbed photons. By that we attribute this effect to the parity of the continuum wave function.Comment: 5 pages, 3 figures, submitted to Phys. Rev. Let

Sub-Cycle Interference upon Tunnel-Ionization by Counterrotating Two-Color Fields

We report on three-dimensional (3D) electron momentum distributions from single ionization of helium by a laser pulse consisting of two counterrotating circularly polarized fields (390 nm and 780 nm). A pronounced 3D low energy structure and sub-cycle interferences are observed experimentally and reproduced numerically using a trajectory based semi-classical simulation. The orientation of the low energy structure in the polarization plane is verified by numerical simulations solving the time dependent Schr\"odinger equation.Comment: 5 pages, 4 figures, PRA Rapid Communications accepte

Classical and quantum-mechanical treatments of nonsequential double ionization with few-cycle laser pulses

We address nonsequential double ionization induced by strong, linearly polarized laser fields of only a few cycles, considering a physical mechanism in which the second electron is dislodged by the inelastic collision of the first electron with its parent ion. The problem is treated classically, using an ensemble model, and quantum-mechanically, within the strong-field and uniform saddle-point approximations. In the latter case, the results are interpreted in terms of "quantum orbits", which can be related to the trajectories of a classical electron in an electric field. We obtain highly asymmetric electron momentum distributions, which strongly depend on the absolute phase, i.e., on the phase difference between the pulse envelope and its carrier frequency. Around a particular value of this parameter, the distributions shift from the region of positive to that of negative momenta, or vice-versa, in a radical fashion. This behavior is investigated in detail for several driving-field parameters, and provides a very efficient method for measuring the absolute phase. Both models yield very similar distributions, which share the same physical explanation. There exist, however, minor discrepancies due to the fact that, beyond the region for which electron-impact ionization is classically allowed, the yields from the quantum mechanical computation decay exponentially, whereas their classical counterparts vanish.Comment: 12 pages revtex, 12 figures (eps files

Double photo-ionization of He near a polarizable surface

We calculate the differential cross-section of the direct double photo-ionization of He physisorbed on a polarizable surface. By including the influence of the surface potential in the correlated two-electron final state wavefunction, we show that the differential cross-section carries detailed information on the electronic correlations at the surface. In particular, photo-emission along opposite directions, which is prohibited in the free space, is allowed if the surface potential is long-ranged.Comment: To appear in Phys. Rev. B - Rapid Comm. - 4 pages, 2 PostScript figures embedde

Identification and Characterization of Post-activated B Cells in Systemic Autoimmune Diseases

Autoimmune diseases (AID) such as systemic lupus erythematosus (SLE), primary Sjögren's syndrome (pSS), and rheumatoid arthritis (RA) are chronic inflammatory diseases in which abnormalities of B cell function play a central role. Although it is widely accepted that autoimmune B cells are hyperactive in vivo, a full understanding of their functional status in AID has not been delineated. Here, we present a detailed analysis of the functional capabilities of AID B cells and dissect the mechanisms underlying altered B cell function. Upon BCR activation, decreased spleen tyrosine kinase (Syk) and Bruton's tyrosine kinase (Btk) phosphorylation was noted in AID memory B cells combined with constitutive co-localization of CD22 and protein tyrosine phosphatase (PTP) non-receptor type 6 (SHP-1) along with hyporesponsiveness to TLR9 signaling, a Syk-dependent response. Similar BCR hyporesponsiveness was also noted specifically in SLE CD27- B cells together with increased PTP activities and increased transcripts for PTPN2, PTPN11, PTPN22, PTPRC, and PTPRO in SLE B cells. Additional studies revealed that repetitive BCR stimulation of normal B cells can induce BCR hyporesponsiveness and that tissue-resident memory B cells from AID patients also exhibited decreased responsiveness immediately ex vivo, suggesting that the hyporesponsive status can be acquired by repeated exposure to autoantigen(s) in vivo. Functional studies to overcome B cell hyporesponsiveness revealed that CD40 co-stimulation increased BCR signaling, induced proliferation, and downregulated PTP expression (PTPN2, PTPN22, and receptor-type PTPs). The data support the conclusion that hyporesponsiveness of AID and especially SLE B cells results from chronic in vivo stimulation through the BCR without T cell help mediated by CD40-CD154 interaction and is manifested by decreased phosphorylation of BCR-related proximal signaling molecules and increased PTPs. The hyporesponsiveness of AID B cells is similar to a form of functional anergy