The WISE InfraRed Excesses around Degenerates (WIRED) Survey

The Wide-field Infrared Survey Explorer (WISE) is a NASA medium class Explorer mission that performed an all sky survey in four infrared bands. We present an overview of the WISE InfraRed Excesses around Degenerates (WIRED) Survey, which has the goals of characterizing white dwarf stars in the WISE bands, confirming objects known to have infrared excess from past observations, and revealing new examples of white dwarfs with infrared excess that can be attributed to unresolved companions or debris disks. We obtained preliminary WISE detections (S/N > 2) in at least one band of 405 white dwarfs from the 9316 unique possible targets in the Sloan Digital Sky Survey Data Release 4 Catalog of Spectroscopically Identified White Dwarfs (not all potential targets were available in the sky coverage used here). A companion paper in this volume discusses specific results from our target detections

The WIRED Survey. IV. New Dust Disks from the McCook & Sion White Dwarf Catalog

We have compiled photometric data from the Wide-field Infrared Survey Explorer All Sky Survey and other archival sources for the more than 2200 objects in the original McCook & Sion Catalog of Spectroscopically Identified White Dwarfs. We applied color-selection criteria to identify 28 targets whose infrared spectral energy distributions depart from the expectation for the white dwarf photosphere alone. Seven of these are previously known white dwarfs with circumstellar dust disks, five are known central stars of planetary nebulae, and six were excluded for being known binaries or having possible contamination of their infrared photometry. We fit white dwarf models to the spectral energy distributions of the remaining ten targets, and find seven new candidates with infrared excess suggesting the presence of a circumstellar dust disk. We compare the model dust disk properties for these new candidates with a comprehensive compilation of previously published parameters for known white dwarfs with dust disks. It is possible that the current census of white dwarfs with dust disks that produce an excess detectable at K-band and shorter wavelengths is close to complete for the entire sample of known WDs to the detection limits of existing near-IR all-sky surveys. The white dwarf dust disk candidates now being found using longer wavelength infrared data are drawn from a previously underrepresented region of parameter space, in which the dust disks are overall cooler, narrower in radial extent, and/or contain fewer emitting grains.Comment: accepted for publication in The Astrophysical Journal; 34 pages, 5 figures, 5 tables; added missing reference in Section 2 (p. 7

A Spitzer Space Telescope Study of the Debris Disks around four SDSS White Dwarfs

We present Spitzer Space Telescope data of four isolated white dwarfs that were previously known to harbor circumstellar gaseous disks. IRAC photometry shows a significant infrared excess in all of the systems, SDSS0738+1835, SDSS0845+2257, SDSS1043+0855 and SDSS1617+1620, indicative of a dusty extension to those disks. The 4.5-micron excesses seen in SDSS0738, SDSS0845, and SDSS1617 are 7.5, 5.7 and 4.5 times the white dwarf contribution, respectively. In contrast, in SDSS1043, the measured flux density at 4.5 microns is only 1.7 times the white dwarf contribution. We compare the measured IR excesses in the systems to models of geometrically thin, optically thick disks, and find that we are able to match the measured SEDs to within 3 sigma of the uncertainties, although disks with unfeasibly hot inner dust temperatures generally provide a better fit than those below the dust sublimation temperature. Possible explanations for the dearth of dust around SDSS1043+0855 are briefly discussed. Including our previous study of SDSS1228+1040, all five white dwarfs with gaseous debris disks have significant amounts of dust around them. It is evident that gas and dust can coexist around these relatively warm, relatively young white dwarfs.Comment: 20 pages, including 4 figures. Accepted to Ap

Two Extrasolar Asteroids with Low Volatile-Element Mass Fractions

Using ultraviolet spectra obtained with the Cosmic Origins Spectrograph on the Hubble Space Telescope, we extend our previous ground-based optical determinations of the composition of the extrasolar asteroids accreted onto two white dwarfs, GD 40 and G241-6. Combining optical and ultraviolet spectra of these stars with He-dominated atmospheres, 13 and 12 polluting elements are confidently detected in GD 40 and G241-6, respectively. For the material accreted onto GD 40, the volatile elements C and S are deficient by more than a factor of 10 and N by at least a factor of 5 compared to their mass fractions in primitive CI chondrites and approach what is inferred for bulk Earth. A similar pattern is found for G241-6 except that S is undepleted. We have also newly detected or placed meaningful upper limits for the amount of Cl, Al, P, Ni and Cu in the accreted matter. Extending results from optical studies, the mass fractions of refractory elements in the accreted parent bodies are similar to what is measured for bulk Earth and chondrites. Thermal processing, perhaps interior to a snow line, appears to be of central importance in determining the elemental compositions of these particular extrasolar asteroids.Comment: 37 pages, 13 figures, 5 tables, ApJ, accepte

Cool Customers in the Stellar Graveyard I: Limits to Extrasolar Planets Around the White Dwarf G29-38

We present high contrast images of the hydrogen white dwarf G 29-38 taken in the near infrared with the Hubble Space Telescope and the Gemini North Telescope as part of a high contrast imaging search for substellar objects in orbit around nearby white dwarfs. We review the current limits on planetary companions for G29-38, the only nearby white dwarf with an infrared excess due to a dust disk. We add our recent observations to these limits to produce extremely tight constraints on the types of possible companions that could be present. No objects $>$ 6 M$_{Jup}$ are detected in our data at projected separations $>$ 12 AU, and no objects $>$ 16 M$_{Jup}$ are detected for separations from 3 to 12 AU, assuming a total system age of 1 Gyr. Limits for companions at separations $<$ 3 AU come from a combination of 2MASS photometry and previous studies of G29-38's pulsations. Our imaging with Gemini cannot confirm a tentative claim for the presence of a low mass brown dwarf. These observations demonstrate that a careful combination of several techniques can probe nearby white dwarfs for large planets and low mass brown dwarfs.Comment: 20 pages, 4 figures, Accepted to Ap

The androgen receptor and signal-transduction pathways in hormone-refractory prostate cancer. Part 2: androgen-receptor cofactors and bypass pathways

Prostate cancer is the second leading cause of cancer related deaths in men from the western world. Treatment of prostate cancer has relied on androgen deprivation therapy for the past 50 years. Response rates are initially high (70-80%), however almost all patients develop androgen escape and subsequently die within 1-2 years. Unlike breast cancer, alternative approaches (chemotherapy and radiotherapy) do not increase survival time. The high rate of prostate cancer mortality is therefore strongly linked to both development of androgen escape and the lack of alternate therapies. AR mutations and amplifications can not explain all cases of androgen escape and post-translational modification of the AR has become an alternative theory. However recently it has been suggested that AR co-activators e.g. SRC-1 or pathways the bypass the AR (Ras/MAP kinase or PI3K/Akt) may stimulated prostate cancer progression independent of the AR. This review will focus on how AR coactivators may act to increase AR transactivation during sub-optimal DHT concentrations and also how signal transduction pathways may promote androgen escape via activation of transcription factors, e.g. AP-1, c-Myc and Myb, that induce cell proliferation or inhibit apoptosis

The WIRED Survey. III. An Infrared Excess around the Eclipsing Post-common Envelope Binary SDSS J030308.35+005443.7

We present the discovery with WISE of a significant infrared excess associated with the eclipsing post-common envelope binary SDSS J030308.35+005443.7, the first excess discovered around a non-interacting white dwarf+main-sequence M dwarf binary. The spectral energy distribution of the white dwarf+M dwarf companion shows significant excess longward of 3 μm. A T_(eff) of 8940 K for the white dwarf is consistent with a cooling age >2 Gyr, implying that the excess may be due to a recently formed circumbinary dust disk of material that extends from the tidal truncation radius of the binary at 1.96 R_☉ out to <0.8 AU, with a total mass of ~10^(20) g. We also construct WISE and follow-up ground-based near-infrared light curves of the system and find variability in the K band that appears to be in phase with ellipsoidal variations observed in the visible. The presence of dust might be due to (1) material being generated by the destruction of small rocky bodies that are being perturbed by an unseen planetary system or (2) dust condensing from the companion's wind. The high inclination of this system and the presence of dust make it an attractive target for M dwarf transit surveys and long-term photometric monitoring

Five Debris Disks Newly Revealed in Scattered Light from the HST NICMOS Archive

We have spatially resolved five debris disks (HD 30447, HD 35841, HD 141943, HD 191089, and HD 202917) for the first time in near-infrared scattered light by reanalyzing archival Hubble Space Telescope (HST)/NICMOS coronagraphic images obtained between 1999 and 2006. One of these disks (HD 202917) was previously resolved at visible wavelengths using HST/Advanced Camera for Surveys. To obtain these new disk images, we performed advanced point-spread function subtraction based on the Karhunen-Loeve Image Projection (KLIP) algorithm on recently reprocessed NICMOS data with improved detector artifact removal (Legacy Archive PSF Library And Circumstellar Environments Legacy program). Three of the disks (HD 30447, HD 35841, and HD 141943) appear edge-on, while the other two (HD 191089 and HD 202917) appear inclined. The inclined disks have been sculpted into rings; in particular, the disk around HD 202917 exhibits strong asymmetries. All five host stars are young (8-40 Myr), nearby (40-100 pc) F and G stars, and one (HD 141943) is a close analog to the young sun during the epoch of terrestrial planet formation. Our discoveries increase the number of debris disks resolved in scattered light from 19 to 23 (a 21% increase). Given their youth, proximity, and brightness (V = 7.2 to 8.5), these targets are excellent candidates for follow-up investigations of planet formation at visible wavelengths using the HST/STIS coronagraph, at near-infrared wavelengths with the Gemini Planet Imager (GPI) and Very Large Telescope (VLT)/SPHERE, and at thermal infrared wavelengths with the James Webb Space Telescope NIRCam and MIRI coronagraphs.Comment: 6 pages, 1 figure, 1 tabl