Oral Hygiene Practices Among Cricketers in Chennai

 Oral hygiene refers to the practice of keeping the mouth, teeth and gums clean and healthy to prevent oral disease. Oral hygiene is often taken for granted but it is essential part of our daily life.Oral hygiene is the practice of maintaining a clean oral cavity to prevent dental diseases such as dental cavities, gingivitis, periodontitis and bad breath. A total of 150 cricketers were involved in the study . Self administered questionnaire related to the oral hygiene practices along with sociodemographic details was prepared and it was distributed through an online survey link. Based on hypotonic and isotonic content of the sports drink , the majority of the participants(58.7%) prefer isotonic sports drinks and the remaining participants( 41.3%) prefer Hypotonic .About 58% of participants eat chocolate regularly. 54.6% of participants agreed that dental erosion affects oral health . 56% of participants think oral health has an impact on sports performance. In the present study, the knowledge,attitude and practice of oral hygiene is moderate.For further improvement, awareness about maintaining good oral health should be created among the public. Erosion can be prevented by educating the subjects about the risks associated with carbonated drinks which is more common among sportsmen and young adults

Graphene nanoribbons/manganese oxide nanocomposite modified electrode for detection of antimicrobial drug nitrofurantoin

The design and development of a new kind of cost-effective electrode material with excellent selectivity and stability are still a great challenge in the field of electrochemical sensors. Recently, researchers have paid more attention to the electrochemical reduction of nitro compounds due to their hazardous nature. Nitro compounds play a vital role in various industrial applications. However, the direct discharge of nitro compounds to the environment as industrial wastewater is harmful. In this study, a nanocomposite made of 1D graphene nanoribbons decorated with manganese dioxide (GNR-MnO2) was prepared to fabricate an electrochemical transducer for the determination of nitrofurantoin (NFT) in biofluids. First, 1D GNR was prepared by unzipping of multiwalled carbon nanotubes. Second, the GNR was decorated with MnO2 by the hydrothermal reduction method. As-prepared GNR-MnO2 nanocomposite was comprehensively characterized by field emission scanning electron microscopy with EDX, XRD, UV–visible, electrochemical impedance spectroscopy, and cyclic voltammetry. Moreover, GNR-MnO2-coated glassy carbon electrode (GCE) exhibited good electrocatalytic activity toward NFT. The electroreduction of NFT was found at −0.40 V which was 50 mV lower than bare GCE. GNR-MnO2 nanocomposite modified GCE showed a well-defined linear reduction peak current for NFT from 10 nM to 1,000 µM. The selectivity of the sensor was also analyzed in the presence of other nitro compounds which confirmed that NFT can be selectively detected at −0.4 V. The GNR-MnO2 modified electrode was also able to separate reduction peaks of other nitro compounds. In addition, the detection of NFT was carried out in human urine samples with a good recovery of 99.60%–98.60%

The Clinical Impact of Copy Number Variants in Inherited Bone Marrow Failure Syndromes

Inherited bone marrow failure syndromes (IBMFSs) comprise a genetically heterogeneous group of diseases with hematopoietic failure and a wide array of physical malformations. Copy number variants (CNVs) were reported in some IBMFSs. It is unclear what impact CNVs play in patients evaluated for a suspected diagnosis of IBMFS. Clinical and genetic data of 323 patients from the Canadian Inherited Marrow Failure Registry from 2001 to 2014, who had a documented genetic work-up, were analyzed. Cases with pathogenic CNVs (at least 1 kilobasepairs) were compared to cases with other mutations. Genotype-phenotype correlations were performed to assess the impact of CNVs. Pathogenic nucleotide-level mutations were found in 157 of 303 tested patients (51.8%). Genome-wide CNV analysis by single nucleotide polymorphism arrays or comparative genomic hybridization arrays revealed pathogenic CNVs in 11 of 67 patients tested (16.4%). In four of these patients, identification of CNV was crucial for establishing the correct diagnosis as their clinical presentation was ambiguous. Eight additional patients were identified to harbor pathogenic CNVs by other methods. Of the 19 patients with pathogenic CNVs, four had compound-heterozygosity of a CNV with a nucleotide-level mutation. Pathogenic CNVs were associated with more extensive non-hematological organ system involvement

Modern Methods for Delineating Metagenomic Complexity

VoRSUNY DownstateEpidemiology and BiostatisticsN/

Geospatial Resolution of Human and Bacterial Diversity with City-Scale Metagenomics

The panoply of microorganisms and other species present in our environment influence human health and disease, especially in cities, but have not been profiled with metagenomics at a city-wide scale. We sequenced DNA from surfaces across the entire New York City (NYC) subway system, the Gowanus Canal, and public parks. Nearly half of the DNA (48%) does not match any known organism; identified organisms spanned 1,688 bacterial, viral, archaeal, and eukaryotic taxa, which were enriched for harmless genera associated with skin (e.g., Acinetobacter). Predicted ancestry of human DNA left on subway surfaces can recapitulate U.S. Census demographic data, and bacterial signatures can reveal a station's history, such as marine-associated bacteria in a hurricane-flooded station. Some evidence of pathogens was found (Bacillus anthracis), but a lack of reported cases in NYC suggests that the pathogens represent a normal, urban microbiome. This baseline metagenomic map of NYC could help long-term disease surveillance, bioterrorism threat mitigation, and health management in the built environment of cities.VoRSUNY DownstateEpidemiology and BiostatisticsN/

A Control Scheme of an Interleaved Fly Back Inverter for Photovoltaic Application to Achieve High Efficiency

The Study shows that how Interleaved fly backinverter is usefulin photovoltaic application in order to achieve higher efficiency for improving the performance. The fly backtopology is basically operated in Discontinuous conduction mode. The main aim of this study to develop the inverter with low cost which will helpin order to achieve the higher efficiency.This reduction of cost is achieved by using flyback inverter topology. The controller performance and inverter design checked by using the simulation result for given particular specification.With help of experimental result it is possible to achieve the efficiency at 86% at full load and power factor which is very close to the unity