Muon Capture on Deuteron and 3He: A Personal Review

The present status of theoretical and experimental studies of muon capture reactions on light nuclei is reviewed. In particular, the recent results for the two reactions 2H(\mu^-,\nu_\mu)nn and 3He(\mu^-,\nu_\mu)3H are presented, and the unresolved discrepancies among different measurements and calculations, open problems, and future developments are discussed.Comment: 19 pages, submitted to International Journal of Modern Physics

Ligand regulation of the quaternary organization of cell surface M3 muscarinic acetylcholine receptors analyzed by fluorescence resonance energy transfer (FRET) imaging and homogenous time-resolved FRET

Flp-In T-REx 293 cells expressing a wild type human M muscarinic acetylcholine receptor construct constitutively and able to express a Receptor Activated Solely by Synthetic Ligand (RASSL) form of this receptor on demand maintained response to the muscarinic agonist carbachol but developed response to clozapine-N-oxide only upon induction of the RASSL. The two constructs co-localized at the plasma membrane and generated strong ratiometric fluorescence resonance energy transfer (FRET) signals consistent with direct physical interactions. Increasing levels of induction of the FRET-donor RASSL did not alter wild type receptor FRET-acceptor levels substantially. However, ratiometric FRET was modulated in a bell-shaped fashion with maximal levels of the donor resulting in decreased FRET. Carbachol, but not the antagonist atropine, significantly reduced the FRET signal. Cell surface homogenous time-resolved FRET, based on SNAP-tag technology and employing wild type and RASSL forms of the human M receptor expressed stably in Flp-In TREx 293 cells, also identified cell surface dimeric/oligomeric complexes. Now, however, signals were enhanced by appropriate selective agonists. At the wild type receptor large increases in FRET signal to carbachol and acetylcholine were concentration-dependent with EC values consistent with the relative affinities of the two ligands. These studies confirm the capacity of the human M muscarinic acetylcholine receptor to exist as dimeric/oligomeric complexes at the surface of cells and demonstrate that the organization of such complexes can be modified by ligand binding. However, conclusions as to the effect of ligands on such complexes may depend on the approach used

Tinjauan Yuridis terhadap Kekuatan Hukum Sertifikat Tanah yang di Keluarkan oleh Pejabat yang Berwenang (Badan Pertanahan Nasional)

Penelitian ini dilakukan dengan tujuan untuk mengetahui bagaimana kewenangan pejabat pembuat akta tanah yang berkaitan dengan pengurusan sertifikat tanah dan bagaimana kekuatan hukum sertifikat tanah yang di keluarkan oleh Badan Pertanahan Nasional. Dengan menggunakan metode penelitian yuridis normatif, maka dapat disimpulkan: 1. Kewenangan pejabat pembuat akta tanah yakni membuat akta otentik mengenai semua perbuatan hukum sebagaimana dimaksud dalam Peraturan Pemerintah No. 37 Tahun 1997 tentang peraturan jabatan pejabat pembuat akta tanah Pasal 2. Pejabat lain yang dalam hal ini yakni Notaris. Berwenang dalam semua perbuatan yang berkaitan dengan pertanahan dalam bentuk akta Otentik dan di bawah tangan sebagaimana wewenang yang diberikan oleh undang-undang maupun yang dikehendaki oleh yang berkepentingan. Sebagaimana yang dimaksud dalam Undang-Undang No. 2 Tahun 2014 tentang Jabatan Notaris Pasal 15. 2. Kekuatan Hukum dari sertifikat tanah yang dikeluarkan oleh Badan Pertanahan Nasional yakni sebagaimana yang tercantum pada Peraturan Pemerintah No. 24 Tahun 1997 tentang Pendaftaran Tanah Pasal 32 ayat (2) yang membuktikan bahwa pembuktian kekuatan hukum sertifikat tanah bersistem negatif tidak murni

Governance of Dual-Use Technologies: Theory and Practice

The term dual-use characterizes technologies that can have both military and civilian applications. What is the state of current efforts to control the spread of these powerful technologies—nuclear, biological, cyber—that can simultaneously advance social and economic well-being and also be harnessed for hostile purposes? What have previous efforts to govern, for example, nuclear and biological weapons taught us about the potential for the control of these dual-use technologies? What are the implications for governance when the range of actors who could cause harm with these technologies include not just national governments but also non-state actors like terrorists? These are some of the questions addressed by Governance of Dual-Use Technologies: Theory and Practice, the new publication released today by the Global Nuclear Future Initiative of the American Academy of Arts and Sciences. The publication's editor is Elisa D. Harris, Senior Research Scholar, Center for International Security Studies, University of Maryland School of Public Affairs. Governance of Dual-Use Technologies examines the similarities and differences between the strategies used for the control of nuclear technologies and those proposed for biotechnology and information technology. The publication makes clear the challenges concomitant with dual-use governance. For example, general agreement exists internationally on the need to restrict access to technologies enabling the development of nuclear weapons. However, no similar consensus exists in the bio and information technology domains. The publication also explores the limitations of military measures like deterrence, defense, and reprisal in preventing globally available biological and information technologies from being misused. Some of the other questions explored by the publication include: What types of governance measures for these dual-use technologies have already been adopted? What objectives have those measures sought to achieve? How have the technical characteristics of the technology affected governance prospects? What have been the primary obstacles to effective governance, and what gaps exist in the current governance regime? Are further governance measures feasible? In addition to a preface from Global Nuclear Future Initiative Co-Director Robert Rosner (University of Chicago) and an introduction and conclusion from Elisa Harris, Governance of Dual-Use Technologiesincludes:On the Regulation of Dual-Use Nuclear Technology by James M. Acton (Carnegie Endowment for International Peace)Dual-Use Threats: The Case of Biotechnology by Elisa D. Harris (University of Maryland)Governance of Information Technology and Cyber Weapons by Herbert Lin (Stanford University

Pengaruh Kualitas Layanan Terhadap Kepuasan Pasien Medical Check Up (Mcu) Pada Rumah Sakit Dr. Ak. Gani Palembang

This final report titled “The impact of the service quality toward the patient satisfaction of medical check-up at RS. DR. AK. GANI Palembang”. The objective of this research is to know the level of patient satisfaction toward the service quality which is given and to know which service quality variable that most significantly influence the patient satisfaction. In analyzing the problems, the writer used interview technique and quesionnaires by distributing questionnaires to every patients who conducted medical check-up with 60 questionnaires that is distributed. In processing the data, the writer used SPSS version 20.0 program. The results showed that the reliability variable and the responsiveness variable had strong influence toward the patient satisfaction and the strongest one was the reliability dimension with 43,4%

Vetoing atmospheric neutrinos in a high energy neutrino telescope

We discuss the possibility to suppress downward atmospheric neutrinos in a high energy neutrino telescope. This can be achieved by vetoing the muon which is produced by the same parent meson decaying in the atmosphere. In principle, atmospheric neutrinos with energies $E_\nu > 10$ TeV and zenith angle up to 60 degree can be vetoed with an efficiency of > 99%. Practical realization will depend on the depth of the neutrino telescope, on the muon veto efficiency and on the ability to identify downward moving neutrinos with a good energy estimation.Comment: 10 pages, 3 figures, accepted for publication in Physical Review