32 research outputs found

    First Report of Dermestes frischii Kugelann (Coleoptera: Dermestidae) on a Human Corpse, South of Iran

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    The necrophagous species of beetles provide useful complementary data to estimate the post-mortem interval in forensic cases. We report, for the first time, Dermestes frischii Kugelann, 1792 larvae from a mummified human body covered with bushes and located in a canal in Sarvestan district, Fars province, south of Iran. The human corpse was a 63 year old male. The time of death was estimated to have been 23 days prior to the finding of the body based on the police investigations and confessions of a suspect. This beetle can be helpful to estimate the time of death in the future

    Cyclin d1 as a useful marker for the differentiation of ewing�s sarcoma from rhabdomyosarcoma

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    Background: The main oncogenic action of CD99 and cyclin D1 biomarkers is referred to any mutation, amplification, and overexpression in cyclin D1 coding gene, altering cell cycle progression as the main mechanism observed in a variety of tumors. A few studies attempted to detect the overexpression of cyclin D1 and CD99 and in certain types of tumors such as Ewing's sarcoma and rhabdomyosarcoma. The present study aimed to assess the prevalence of CD99 and cyclin D1 overexpression in these two types of tumors. We also described this overexpression according to the patients and tumor indicators. Methods: This cross-sectional survey was performed on 30 consecutive patients with Ewing's sarcoma and 22 patients with rhabdomyosarcoma and hospitalized in Shafa hospital in Tehran between 2009 and 2014. The assessment of CD99 and cyclin D1 markers was based on immunohistochemical assessment using the formalin fixed and paraffin embedded tissue samples of the two tumors. Results: Almost all Ewing's sarcomas had membranous patterns of CD99 while this marker was negative in most patients with rhabdomyosarcoma. Therefore, detecting membranous CD99 could specifically detect Ewing's sarcoma and distinguish it from rhabdomyosarcoma. Moreover, contrary to rhabdomyosarcoma which is accompanied with lower cyclin D1 intensity, all Ewing's sarcomas were characterized by moderate to severe cyclin D1 intensity. Similarly, almost all those with Ewing's sarcoma had diffuse cyclin D1 extension; whereas, the pattern of cyclin D1 extension in rhab-domyosarcoma was mostly negative or focal. Conclusion: The detection of CD99 and cyclin D1 overexpression and their intensity and extension patterns can specifically distinguish Ewing's sarcoma from rhabdomyosarcoma. © 2020, Shiraz University of Medical Sciences. All rights reserved

    Childhood maltreatment and adulthood victimization:An evidence-based model

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    There is ample evidence showing that childhood maltreatment increases two to three fold the risk of victimization in adulthood. Various risk factors, including posttraumatic stress disorder (PTSD) symptoms, dissociation, self-blame, and alcohol abuse are related to revictimization. Although previous research examined associations between risk factors for revictimization, the evidence is limited and the proposed models mostly include a handful of risk factors. Therefore, it is critical to investigate a more comprehensive model explaining the link between childhood maltreatment and adulthood (re)victimization. Accordingly, this study tested a data-driven theoretical path model consisting of 33 variables (and their associations) that could potentially enhance understanding of factors explaining revictimization. Cross-sectional data derived from a multi-wave study were used for this investigation. Participants (N = 2156, age mean = 19.94, SD = 2.89) were first-year female psychology students in the Netherlands and New Zealand, who responded to a battery of questionnaires and performed two computer tasks. The path model created by structural equation modelling using modification indices showed that peritraumatic dissociation, PTSD symptoms, trauma load, loneliness, and drug use were important mediators. Attachment styles, maladaptive schemas, meaning in life, and sex motives connected childhood maltreatment to adulthood victimization via other factors (i.e., PTSD symptoms, risky sex behavior, loneliness, emotion dysregulation, and sex motives). The model indicated that childhood maltreatment was associated with cognitive patterns (e.g., anxious attachment style), which in turn were associated with emotional factors (e.g., emotion dysregulation), and then with behavioral factors (e.g., risky sex behavior) resulting in revictimization. The findings of the study should be interpreted in the light of the limitations. In particular, the cross-sectional design of the study hinders us from ascertaining that the mediators preceded the outcome variable.</p

    Rockfall analysis in the area of Kakia Skala, Greece

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    Because rockfalls cause significant hazard on human activities and infrastructure, the rockfall analysis is considered to be very important along roads and on other geotechnical works. Especially, in Greece owing to the complexity of geological structure, the tectonic characteristics, the climate and the high seismicity, this analysis is of great importance. This paper presents the topographical, geological, tectonic and seismic features and determines the Rock Mass Rating and Rockfall Hazard Rating System values of the tectonically disturbed limestones in the area of “Kakia Skala”, which is part of the “Patra–Athens–Thessaloniki–Evzoni (P.A.TH.E.)” motorway—one of the most major highways in Greece. For this reason, after geological and geomorphological investigations, bibliographic references and the characteristics of the road construction (tunnels, embankments, trenches, etc.), the most dangerous positions were identified (eight). Finally, the two most dangerous sites were selected for separate rockfall analysis. The RocFall software is used for the estimation of the unstable blocks trajectories and their kinematic characteristics. The appropriate support measure, with the right dimensions, is selected according to the kinetic energy of the falling rocks, and it is placed at the appropriate location. © 2021, Saudi Society for Geosciences

    Non-stationary signal analysis of the von Kármán vortex shedding in the wake of a fluttering airfoil

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    Stationary data lend themselves well to the Fourier decomposition into harmonic components. Conversely, spectral characteristics of non-stationary data vary with time, and hence do not generally admit the application of Fourier transform. In order to investigate the localized time-frequency characteristics of non-stationary data, the notions of instantaneous frequency and amplitude are invoked. These concepts are applied to the von Kármán vortex shedding observed in the wake of a selfsustained pitching airfoil. For this range of Reynolds numbers (104 -105), it has been reported that at any given airspeed the shedding frequency of the vortex street varies with angle of attack (AOA), ranging from the Strouhal number St ≈ 0:6 at zero AOA and tending to St ≈ 0:1 for high AOA. For the pitching motion, which originates from a positive energy transfer from the flow to the airfoil due to negative aerodynamic damping, the von Kármán vortex shedding frequency varies with pitch angle hence with time. Hilbert transform provides a robust estimate of instantaneous frequency through the definition of analytic signals. However, Hilbert transform provides meaningful instantaneous frequency for only monocomponent signals. To overcome this difficulty, the Hilbert-Huang transform is commonly exploited. In this paper, both the Hilbert and Hilbert-Huang transforms are applied in order to capture the instantaneous vortex shedding frequency. For multicomponent signals Empirical Mode Decomposition (EMD) splits the signal to monocomponent signals, namely Intrinsic Mode Functions, through a so-called sifting process. Application of Hilber

    Evaluation of Association between Perceived Stress, Anxiety, Depression, Salivary Alpha-Amylase and Salivary Cortisol with Chronic Periodontitis

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    Introduction: Chronic Periodontitis is a multifactorial inflammatory disease, which is caused by certain series of bacteria in oral biofilm and leads to teeth supporting tissue destruction. Stress, depression and anxiety can affect periodontium health through variable different mechanisms. Cortisol is secreted from adrenocorticotropic glands in pituitary gland and can be used as index to determine psychological stress rate. Alpha-amylase is an salivary gland enzyme which is regulated through sympatric nervous system. The aim of the following study is to compare between different biomarkers related to the emotional stress, anxiety and depression in saliva and their role on periodontal health and also the correlation between periodontal parameters, stress, depression and anxiety. Method: 90 patients with age ranged from 35 to 45 years were participated in the study. Salivary cortisol and alpha-amylase levels were measured in them. Levels of Stress, Anxiety and Depresion were evaluated using questionnaires. The relationship between psychological and biochemical factors with chronic Periodontitis were assessed. The results were analyzed by statistical analysis. Results: The mean concentration of salivary cortisol was 7.87±4.37 ng/ml in the case group and 4.33±2.11 ng/ml in the control group. The difference was statistically significant (p&lt;0.001). The mean concentration of salivary alphaamylase was 3569.27±101.22 U/L in the case group and 3343.44±171.09 U/L in the control group. The difference was statistically significant (p&lt;0.001). The mean stress score was 24.28±3.09 in the case group and 22.96±3.61 in the control group. The difference between two groups was statistically significant (p&lt;0.001). The difference between two groups was statistically significant (p&lt;0.001). The mean anxiety score was 44.11±4.59 in the case group and 36.47±4.30 in the control group, which was statistically significant (p&lt;0.001). The mean depression score was 19.96±3.58 in the case group and 13.13±3.91 in the control group. The difference between two groups was statistically significant (p&lt;0.001). Conclusion: The findings of these study showed that psychological factors like emotional stress, depression and anxiety and biochemical factors including salivary cortisol and alpha-amylase are higher in patients with moderate to severe chronic periodontitis in comparison to healthy people. also Anxiety and depression are stronger predictors of periodontitis than acute stress and cortisol.</jats:p
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