990 research outputs found

    Open source health systems

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    Current driven electrostatic and electromagnetic ion cyclotron instabilities

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    Growth rates and parameter dependences are calculated for the current driven instabilities of electrostatic (with finite-beta corrections) and electromagnetic ion cyclotron waves. For 0.25 (T sub e)/(T sub i) 2.5, ion cyclotron waves have large growth rates, while ion acoustic waves are still stable. In fusion devices, where electrostatic waves may be stable, electromagnetic ion cyclotron waves are unstable for beta sub i 0.001

    Influence of the Lower Hybrid Drift Instability on the onset of Magnetic Reconnection

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    Two-dimensional and three-dimensional kinetic simulation results reveal the importance of the Lower-Hybrid Drift Instability LHDI to the onset of magnetic reconnection. Both explicit and implicit kinetic simulations show that the LHDI heats electrons anisotropically and increases the peak current density. Linear theory predicts these modifications can increase the growth rate of the tearing instability by almost two orders of magnitude and shift the fastest growing modes to significantly shorter wavelengths. These predictions are confirmed by nonlinear kinetic simulations in which the growth and coalescence of small scale magnetic islands leads to a rapid onset of large scale reconnection

    Cross-cultural adaptation and validation of the “spinal cord injury-falls concern scale” in the Italian population

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    Study design: Psychometrics study. Objective: The objective of this study was to develop an Italian version of the Spinal Cord Injury-Falls Concern Scale (SCI-FCS) and examine its reliability and validity. Setting: Multicenter study in spinal units in Northern and Southern Italy. The scale also was administered to non-hospitalized outpatient clinic patients. Methods: The original scale was translated from English to Italian using the “Translation and Cultural Adaptation of Patient-Reported Outcomes Measures” guidelines. The reliability and validity of the culturally adapted scale were assessed following the “Consensus-Based Standards for the Selection of Health Status Measurement Instruments” checklist. The SCI-FCS-I internal consistency, inter-rater, and intra-rater reliability were examined using Cronbach’s alpha coefficient and the intraclass correlation coefficient, respectively. Concurrent validity was evaluated using Pearson’s correlation coefficient with the Italian version of the short form of the Wheelchair Use Confidence Scale for Manual Wheelchair Users (WheelCon-M-I-short form). Results: The Italian version of the SCI-FCS-I was administered to 124 participants from 1 June to 30 September 2017. The mean ± SD of the SCI-FCS-I score was 16.73 ± 5.88. All SCI-FCS items were either identical or similar in meaning to the original version’s items. Cronbach’s α was 0.827 (p < 0.01), the inter-rater reliability was 0.972 (p < 0.01), and the intra-rater reliability was 0.973 (p < 0.01). Pearson’s correlation coefficient of the SCI-FCS-I scores with the WheelCon-M-I-short form was 0.56 (p < 0.01). Conclusions: The SCI-FCS-I was found to be reliable and a valid outcome measure for assessing manual wheelchair concerns about falling in the Italian population

    Three-Dimensional Fermi Surface of Overdoped La-Based Cuprates

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    We present a soft x-ray angle-resolved photoemission spectroscopy study of the overdoped high-temperature superconductors La2x_{2-x}Srx_xCuO4_4 and La1.8x_{1.8-x}Eu0.2_{0.2}Srx_xCuO4_4. In-plane and out-of-plane components of the Fermi surface are mapped by varying the photoemission angle and the incident photon energy. No kzk_z dispersion is observed along the nodal direction, whereas a significant antinodal kzk_z dispersion is identified. Based on a tight-binding parametrization, we discuss the implications for the density of states near the van-Hove singularity. Our results suggest that the large electronic specific heat found in overdoped La2x_{2-x}Srx_xCuO4_4 can not be assigned to the van-Hove singularity alone. We therefore propose quantum criticality induced by a collapsing pseudogap phase as a plausible explanation for observed enhancement of electronic specific heat

    Role of surface roughness in hard x-ray emission from femtosecond laser produced copper plasmas

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    The hard x-ray emission in the energy range of 30-300 keV from copper plasmas produced by 100 fs, 806 nm laser pulses at intensities in the range of 10151016^{15}-10^{16} W cm2^{-2} is investigated. We demonstrate that surface roughness of the targets overrides the role of polarization state in the coupling of light to the plasma. We further show that surface roughness has a significant role in enhancing the x-ray emission in the above mentioned energy range.Comment: 5 pages, 4 figures, to appear in Phys. Rev.

    Putting into Question the Imaginary of Recovery: A Dialectical Reading of the Global Financial Crisis and its Aftermath

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    In this article we put into question the discourses that emerged during the Global Financial Crisis (GFC) and that coalesced around a particular socio-economic imaginary of ?recovery? over the period 2009-2012. Our reading of these discourses is very much guided by the notion of the dialectic as developed by Fredric Jameson, and as such this paper can be read as attempt to put his theoretical ideas to work. Through our dialectical reading we aim to create a certain estrangement effect that makes the imaginary of recovery seem very odd and unnatural. In order to achieve such an effect we postulate four theses which are deliberately antagonistic: first, that there has been no ?crisis of capitalism?; second, that we must change the valence of the GFC from negative to positive; third, that the relationship between finance capitalism and ?free markets? is deeply contradictory; and fourth, that we must resist the regulation discourse

    Prices, productivity, and wage bargaining in open economies

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    According to the standard union bargaining model, unemployment benefits should have big effects on wages, but product market prices and productivity should play no role in the wage bargain. We formulate an alternative strategic bargaining model, where labour and product market conditions together determine wages. A wage equation is derived and estimated on aggregate data for the Nordic countries. Wages are found to depend on unemployment and the replacement ratio, but also on productivity, international prices and exchange rates. There is evidence of considerable nominal wage rigidity. Exchange rate changes have large and persistent effects on competitiveness

    The mechanisms of action of metformin

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    Metformin is a widely-used drug that results in clear benefits in relation to glucose metabolism and diabetes-related complications. The mechanisms underlying these benefits are complex and still not fully understood. Physiologically, metformin has been shown to reduce hepatic glucose production, yet not all of its effects can be explained by this mechanism and there is increasing evidence of a key role for the gut. At the molecular level the findings vary depending on the doses of metformin used and duration of treatment, with clear differences between acute and chronic administration. Metformin has been shown to act via both AMP-activated protein kinase (AMPK)-dependent and AMPK-independent mechanisms; by inhibition of mitochondrial respiration but also perhaps by inhibition of mitochondrial glycerophosphate dehydrogenase, and a mechanism involving the lysosome. In the last 10 years, we have moved from a simple picture, that metformin improves glycaemia by acting on the liver via AMPK activation, to a much more complex picture reflecting its multiple modes of action. More work is required to truly understand how this drug works in its target population: individuals with type 2 diabetes

    Laser excitation of the n=3 level of positronium for antihydrogen production

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    We demonstrate the laser excitation of the n = 3 state of positronium (Ps) in vacuum. A combination of a specially designed pulsed slow positron beam and a high-efficiency converter target was used to produce Ps. Its annihilation was recorded by single-shot positronium annihilation lifetime spectroscopy. Pulsed laser excitation of the n = 3 level at a wavelength lambda approximate to 205 nm was monitored via Ps photoionization induced by a second intense laser pulse at lambda = 1064 nm. About 15% of the overall positronium emitted into vacuum was excited to n = 3 and photoionized. Saturation of both the n = 3 excitation and the following photoionization was observed and explained by a simple rate equation model. The positronium's transverse temperature was extracted by measuring the width of the Doppler-broadened absorption line. Moreover, excitation to Rydberg states n = 15 and 16 using n = 3 as the intermediate level was observed, giving an independent confirmation of excitation to the 3 P-3 state
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