Pure xenon hexafluoride prepared for thermal properties studies

Preparation of a xenon hexafluoride and sodium fluoride salt yields a sample of the highest possible purity for use in thermal measurements. The desired hexafluoride can easily be freed from the common contaminants, xenon tetra-fluoride, xenon difluoride, and xenon oxide tetrafluoride, because none of these compounds reacts with sodium fluoride

Quantum Metropolis Sampling

The original motivation to build a quantum computer came from Feynman who envisaged a machine capable of simulating generic quantum mechanical systems, a task that is believed to be intractable for classical computers. Such a machine would have a wide range of applications in the simulation of many-body quantum physics, including condensed matter physics, chemistry, and high energy physics. Part of Feynman's challenge was met by Lloyd who showed how to approximately decompose the time-evolution operator of interacting quantum particles into a short sequence of elementary gates, suitable for operation on a quantum computer. However, this left open the problem of how to simulate the equilibrium and static properties of quantum systems. This requires the preparation of ground and Gibbs states on a quantum computer. For classical systems, this problem is solved by the ubiquitous Metropolis algorithm, a method that basically acquired a monopoly for the simulation of interacting particles. Here, we demonstrate how to implement a quantum version of the Metropolis algorithm on a quantum computer. This algorithm permits to sample directly from the eigenstates of the Hamiltonian and thus evades the sign problem present in classical simulations. A small scale implementation of this algorithm can already be achieved with today's technologyComment: revised versio

Simulating adiabatic evolution of gapped spin systems

We show that adiabatic evolution of a low-dimensional lattice of quantum spins with a spectral gap can be simulated efficiently. In particular, we show that as long as the spectral gap \Delta E between the ground state and the first excited state is any constant independent of n, the total number of spins, then the ground-state expectation values of local operators, such as correlation functions, can be computed using polynomial space and time resources. Our results also imply that the local ground-state properties of any two spin models in the same quantum phase can be efficiently obtained from each other. A consequence of these results is that adiabatic quantum algorithms can be simulated efficiently if the spectral gap doesn't scale with n. The simulation method we describe takes place in the Heisenberg picture and does not make use of the finitely correlated state/matrix product state formalism.Comment: 13 pages, 2 figures, minor change

Timing accuracy of the Swift X-Ray Telescope in WT mode

The X-Ray Telescope (XRT) on board Swift was mainly designed to provide detailed position, timing and spectroscopic information on Gamma-Ray Burst (GRB) afterglows. During the mission lifetime the fraction of observing time allocated to other types of source has been steadily increased. In this paper, we report on the results of the in-flight calibration of the timing capabilities of the XRT in Windowed Timing read-out mode. We use observations of the Crab pulsar to evaluate the accuracy of the pulse period determination by comparing the values obtained by the XRT timing analysis with the values derived from radio monitoring. We also check the absolute time reconstruction measuring the phase position of the main peak in the Crab profile and comparing it both with the value reported in literature and with the result that we obtain from a simultaneous Rossi X-Ray Timing Explorer (RXTE) observation. We find that the accuracy in period determination for the Crab pulsar is of the order of a few picoseconds for the observation with the largest data time span. The absolute time reconstruction, measured using the position of the Crab main peak, shows that the main peak anticipates the phase of the position reported in literature for RXTE by ~270 microseconds on average (~150 microseconds when data are reduced with the attitude file corrected with the UVOT data). The analysis of the simultaneous Swift-XRT and RXTE Proportional Counter Array (PCA) observations confirms that the XRT Crab profile leads the PCA profile by ~200 microseconds. The analysis of XRT Photodiode mode data and BAT event data shows a main peak position in good agreement with the RXTE, suggesting the discrepancy observed in XRT data in Windowed Timing mode is likely due to a systematic offset in the time assignment for this XRT read out mode.Comment: 6 pages, 4 figures. Accepted for publication on Astronomy&Astrophysic

Late-Time X-ray Flares during GRB Afterglows: Extended Internal Engine Activity

Observations of gamma ray bursts (GRBs) with Swift produced the initially surprising result that many bursts have large X-ray flares superimposed on the underlying afterglow. These flares were sometimes intense, rapid, and late relative to the nominal prompt phase. The most intense of these flares was observed by XRT with a flux >500 the afterglow. This burst then surprised observers by flaring again after >10000 s. The intense flare can be most easily understood within the context of the standard fireball model, if the internal engine that powers the prompt GRB emission is still active at late times. Recent observations indicate that X-ray flares are detected in ~1/3 of XRT detected afterglows. By studying the properties of the varieties of flares (such as rise/fall time, onset time, spectral variability, etc.) and relating them to overall burst properties, models of flare production and the GRB internal engine can be constrained.Comment: To appear in the proceedings of the 16th Annual October Astrophysics Conference in Maryland "Gamma Ray Bursts in the Swift Era

High urinary tungsten concentration is associated with stroke in the National Health and Nutrition Examination Survey 1999-2010.

Published onlineClinical TrialMulticenter StudyResearch Support, Non-U.S. Gov'tBACKGROUND: In recent years there has been an exponential increase in tungsten demand, potentially increasing human exposure to the metal. Currently, the toxicology of tungsten is poorly understood, but mounting evidence suggests that both the elemental metal and its alloys have cytotoxic effects. Here, we investigate the association between tungsten and cardiovascular disease (CVD) or stroke using six waves of the National Health and Nutrition Examination Survey (NHANES). METHODS: We investigated associations using crude and adjusted logistic regression models in a cohort of 8614 adults (18-74 years) with 193 reported stroke diagnoses and 428 reported diagnoses of CVD. We also stratified our data to characterize associations in a subset of younger individuals (18-50 years). RESULTS: Elevated tungsten concentrations were strongly associated with an increase in the prevalence of stroke, independent of typical risk factors (Odds Ratio (OR): 1.66, 95% Confidence Interval (95% CI): 1.17, 2.34). The association between tungsten and stroke in the young age category was still evident (OR: 2.17, 95% CI: 1.33, 3.53). CONCLUSION: This study represents the most comprehensive analysis of the human health effects of tungsten to date. Individuals with higher urinary tungsten concentrations have double the odds of reported stroke. We hypothesize that the pathological pathway resulting from tungsten exposure may involve oxidative stress.This work was supported by funding from University of Exeter Medical School. No funding organization or sponsor played any part in the design or conduct of the study, in the analysis or interpretation of the data, or preparation, review, or approval of the manuscript. The European Centre for the Environment and Human Health (part of the University of Exeter Medical School) is supported by investment from the ERDF (European Regional Development Fund) and ESF (European Social Fund) Convergence Programmed for Cornwall and the Isles of Scilly. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

The seven year Swift-XRT point source catalog (1SWXRT)

Swift is a multi-wavelength observatory specifically designed for gamma-ray burst (GRB) astronomy that is operational since 2004. Swift is also a very flexible multi-purpose facility that supports a wide range of scientific fields such as active galactic nuclei, supernovae, cataclysmic variables, Galactic transients, active stars and comets. The Swift X-ray Telescope (XRT) has collected more than 150 Ms of observations in its first seven years of operations. We present the list of all the X-ray point sources detected in XRT imaging data taken in photon counting mode during the first seven years of Swift operations. All these point-like sources, excluding the Gamma-Ray Bursts (GRB), will be stored in a catalog publicly available (1SWXRT). We consider all XRT observations with exposure time > 500 s taken in the period 2005-2011. Data were reduced and analyzed with standard techniques and a list of detected sources for each observation was produced. A careful visual inspection was performed to remove extended, spurious and piled-up sources. Positions, count rates, fluxes and the corresponding uncertainties were computed. We have analyzed more than 35,000 XRT fields, with exposures ranging between 500 s and 100 ks, for a total exposure time of 140 Ms. The catalog includes ~ 89,000 entries, of which almost 85,000 are not affected by pile-up and are not GRBs. Since many XRT fields were observed several times, we have a total of ~36,000 distinct celestial sources. We computed count rates in three energy bands: 0.3-10 keV (Full, or F), 0.3-3 keV (Soft, or S) and 2-10 keV (Hard, or H). Each entry has a detection in at least one of these bands. In particular, we detect ~ 80,000, ~ 70,000 and ~ 25,500$ in the F, S and H band, respectively. Count rates were converted into fluxes in the 0.5-10, 0.5-2 and 2-10 keV bands. Some possible scientific uses of the catalog are also highlighted.Comment: 11 pages, 15 ps figures, accepted for publication in A&A. Abstract shortened with respect to the original versio

Patterns of participation over four rounds of annual fecal immunochemical test-based screening for colorectal cancer: what predicts rescreening?

Published online: 01 August 2017Background: Participation at the recommended intervals is critical for screening to be effective in reducing colorectal cancer (CRC) incidence. This study describes patterns of screening participation over four rounds of fecal immunochemical testing (FIT) to identify whether demographic variables and prior screening satisfaction are significantly associated with patterns of re-participation. Methods: Baseline surveys were mailed to 4000 South Australians randomly selected from the electoral-roll. Respondents (n = 1928/48.2%) were offered four annual FIT rounds. Screening participation and satisfaction at each round were recorded. Results: Study participation was 58.5, 66.9, 73.1 and 71.4% respectively over four rounds. Three participation patterns were described: consistent participation (43.1%), consistent non-participation (26.4%) and inconsistent participation (changeable; 30.5%), including intermittent and sustained change patterns. Sustained change described those who changed participatory behavior and then maintained for at least two rounds (n = 375/19.5%). Older people, and those not working were most likely to sustain participation. Younger invitees, especially men, were more likely to change participatory behavior and sustain the change. People with higher disadvantage, less education, not working and with no prior (pre-trial) screening experience were more likely to start participating and drop out. People dissatisfied with a prior screening test, including finding aspects embarrassing or unpleasant, were also more likely not to participate in annual screening or to drop out. Conclusions: The findings identify those at risk of non- or inconsistent participation in rescreening. They should aid targeting of interventions for demographic groups at risk and ensuring screening experiences are not perceived as unpleasant or difficult.Joanne M. Osborne, Carlene Wilson, Amy Duncan, Stephen R. Cole, Ingrid Flight, Deborah Turnbull, Donna L. Hughes and Graeme P. Youn

Typical local measurements in generalised probabilistic theories: emergence of quantum bipartite correlations

What singles out quantum mechanics as the fundamental theory of Nature? Here we study local measurements in generalised probabilistic theories (GPTs) and investigate how observational limitations affect the production of correlations. We find that if only a subset of typical local measurements can be made then all the bipartite correlations produced in a GPT can be simulated to a high degree of accuracy by quantum mechanics. Our result makes use of a generalisation of Dvoretzky's theorem for GPTs. The tripartite correlations can go beyond those exhibited by quantum mechanics, however.Comment: 5 pages, 1 figure v2: more details in the proof of the main resul