SYNTHESES OF SOME PHENOXATHIIN DERIVATIVES WITH ANTIMICROBIAL ACTIVITY

Antimicrobial activity has been studied on eighteen substances of phenoxathiin class (six of them being not yet described in the literature) evincing the fact that the oxidizing of the sulfur atom in position 10 leads to a severe decrease of the antibacterial activity.</jats:p

EXOTIC CONGENITAL SCOLIOSIS – THE EFFECTS OF EARLY ARTHRODESIS

Aim. The article presents the difficulties encountered in the treatment of exotic scoliosis and the optimal treatment options for this pathology. Material and method. The case presentation of an exotic scoliosis with T6-T11 vertebral block with hemivertebrae, rib fusions and rib agenesis on the concave side, L1-T12 butterfly vertebrae, L2 hemivertebra and lumbar rachischizis, associated with a diastematomyelic bony spur at T12-L1 level, previous operated, requiring surgical reintervention. Results. Surgical decisions not optimized for each patient may lead to worsening of evolution and raise difficulties in later treatment. Discussions. The resection of the hemivertebra and spinal fusion limited to 2 levels is the optimal treatment for congenital scoliosis that corrects the scoliosis curve and stops progression. The VEPTR device is the most effective choice to ensure pulmonary development compatible with life in patients with thoracic insufficiency syndrome. Conclusions. Exotic scoliosis is a challenging pathology that requires prognosis of development in order to be able to choose the optimal treatment to ensure the growth and development of the thoracic cavity, the pulmonary system and the spinal cords