Signatures of sneutrino dark matter in an extension of the CMSSM

Current data (LHC direct searches, Higgs mass, dark matter-related bounds) severely affect the constrained minimal SUSY standard model (CMSSM) with neutralinos as dark matter candidates. But the evidence for neutrino masses coming from oscillations requires extending the SM with at least right-handed neutrinos with a Dirac mass term. In turn, this implies extending the CMSSM with right-handed sneutrino superpartners, a scenario we dub $\tilde\nu$CMSSM. These additional states constitute alternative dark matter candidates of the superWIMP type, produced via the decay of the long-lived next-to-lightest SUSY particle (NLSP). Here we consider the interesting and likely case where the NLSP is a $\tilde{\tau}$: despite the modest extension with respect to the CMSSM this scenario has the distinctive signatures of heavy, stable charged particles. After taking into account the role played by neutrino mass bounds and the specific cosmological bounds from the big bang nucleosynthesis in selecting the viable parameter space, we discuss the excellent discovery prospects for this model at the future runs of the LHC. We show that it is possible to probe $\tilde{\tau}$ masses up to 600 GeV at the 14 TeV LHC with $\mathcal{L} = 1100$ fb$^{-1}$ when one considers a pair production of staus with two or more hard jets through all SUSY processes. We also show the complementary discovery prospects from a direct $\tilde{\tau}$ pair production, as well as at the new experiment MoEDAL.Comment: 31 pages, 6 figures and 5 tables; v2 : discussions and references added, conclusions unchanged. To appear in JHE

Molecular detection and phylogenetic analysis of Peste des petits ruminants virus circulating in small ruminants in eastern Amhara region, Ethiopia

Background: Peste des Petits Ruminants (PPR) is a severe, highly infectious and fatal viral disease of small ruminants. Four lineages of PPR virus have been identified globally based on sequence analysis of the nucleoprotein (N) and fusion (F) gene. The aim of this study was to isolate and genetically characterize recently circulating PPR virus in small ruminants in the eastern Amhara region in Ethiopia. A total of 28 anti-mortem samples (gum debris, nasal and ocular swab) were collected from clinically suspicious animals and examined for the presence of PPRV by a one-step RT-PCR assay. Samples positive with RT-PCR were subjected to isolation of the virus which were subsequently genetically characterized by sequencing of the nucleoprotein (N) gene and phylogenetic analysis of PPR virus (PPRV) strains. Results: Of the 28 clinical samples examined, 46.4% were positive with RT-PCR for viral nucleic acid. The PPRV was successfully isolated on CHS-20 cell line with the ovine signaling lymphocyte activation molecule (SLAM) receptor expressed on the cell surface and confirmed with RT-PCR and IFAT assay. The nucleotide sequence and phylogenetic analysis indicated that the PPRV obtained were clustered genetically with Lineage IV isolates of the virus. Conclusion: The successful isolation of the virus and molecular findings of this study confirmed active lineage IV PPRV infections among populations of sheep and goats in eastern Amhara, suggesting risks for potential spread of the disease to currently free areas. Thus, we recommend systematic vaccination to contain outbreaks in affected districts and geographically linked surrounding districts to which the disease could potentially spread due to different epidemiological linkages

Seven exercises planned to stimulate the flow of ideas in creative composition

Thesis (Ed.M.)--Boston Universit

Control of morbillivirus replication by RNAI

The Morbillivirus genus includes measles virus (MV), peste des petits ruminants virus (PPRV) and rinderpest virus (RPV). Although preventive vaccines are available against these three viruses, efficient therapeutics for virus control under emergency situations are desirable. Inhibition of morbillivirus replication can be achieved by post-transcriptional silencing of the nucleoprotein (N) gene by RNA interference (RNAi). The viral N protein, a well conserved protein among the genus, plays a central role in the replication of the virus. Using a comprehensive siRNA-based screening of the conserved sequences of the N gene, we have identified, three common positions on the N gene, for the design of siRNA evenly effectives for PPRV, RPV and MV. siRNA silencing resulted in more than 80% decrease of the viral replication in infected Vero cell, as shown by real-time quantitative PCR, flow cytometry and virus titration. In a second step, a recombinant replication-defective human type 5 adenovirus (Ad-5) encoding one of the functional sequences directed against the N gene of PPRV was constructed and shown to reduce the PPRV replication in vitro. These results illustrate that adenovirus vector could be a promising candidate for the development of siRNA antiviral treatments against morbilliviruses

Dirac Neutrino Dark Matter

We investigate the possibility that dark matter is made of heavy Dirac neutrinos with mass in the range [O(1) GeV- a few TeV] and with suppressed but non-zero coupling to the Standard Model Z as well as a coupling to an additional Z' gauge boson. The first part of this paper provides a model-independent analysis for the relic density and direct detection in terms of four main parameters: the mass, the couplings to the Z, to the Z' and to the Higgs. These WIMP candidates arise naturally as Kaluza-Klein states in extra-dimensional models with extended electroweak gauge group SU(2)_L* SU(2)_R * U(1). They can be stable because of Kaluza-Klein parity or of other discrete symmetries related to baryon number for instance, or even, in the low mass and low coupling limits, just because of a phase-space-suppressed decay width. An interesting aspect of warped models is that the extra Z' typically couples only to the third generation, thus avoiding the usual experimental constraints. In the second part of the paper, we illustrate the situation in details in a warped GUT model.Comment: 35 pages, 25 figures; v2: JCAP version; presentation and plots improved, results unchange

On Passion and Sports Fans:A Look at Football

The purpose of the present research was to test the applicability of the Dualistic Model of Passion (Vallerand et al., 2003) to being a sport (football) fan. The model posits that passion is a strong inclination toward an activity that individuals like (or even love), that they value, and in which they invest time and energy. Furthermore, two types of passion are proposed: harmonious and obsessive passion. While obsessive passion entails an uncontrollable urge to engage in the passionate activity, harmonious passion entails a sense of volition while engaging in the activity. Finally, the model posits that harmonious passion leads to more adaptive outcomes than obsessive passion. Three studies provided support for this dualistic conceptualization of passion. Study 1 showed that harmonious passion was positively associated with adaptive behaviours (e.g., celebrate the team’s victory), while obsessive passion was rather positively associated with maladaptive behaviours (e.g., to risk losing one’s employment to go to the team’s game). Study 2 used a short Passion Scale and showed that harmonious passion was positively related to the positive affective life of fans during the 2006 FIFA World Cup, psychological health (self-esteem and life satisfaction), and public displays of adaptive behaviours (e.g., celebrating one’s team victory in the streets), while obsessive passion was predictive of maladaptive affective life (e.g., hating opposing team’s fans) and behaviours (e.g., mocking the opposing team’s fans). Finally, Study 3 examined the role of obsessive passion as a predictor of partner’s conflict that in turn undermined partner’s relationship satisfaction. Overall, the present results provided support for the Dualistic Model of Passion. The conceptual and applied implications of the findings are discussed

D 5.5.2. Report on near-market consumer testing of new improved products and substitutes in Africa. Project AFTER “African Food Tradition rEvisited by Research”

In this deliverable, the reengineered products relating to groups 1 to 3 are tested by consumers in Africa in order to test whether the acceptance meets consumer needs. The summaries are by group. These products were widely different and tested in differing cultures and situations. A common feature, however, is that all products are already commonly consumed by the communities and accepted, particularly with respect to the baseline products. Some products were found to be more acceptable (Gowe and Akpan in Benin, Kenkey in Ghana, Kong and Lanhouin in Senegal, Bissap and Baobab in Senegal), some of similar acceptance (Kitoza in Madagascar) and some were less acceptable (Kishk Sa'eedi in Egypt and Jaabi in Cameroon). Ways forward are discussed in all cases. Group 1: The reengineered group 1 products had mixed acceptance to consumers. Ones that were highly accepted were the reengineered Akpan which was highly accepted regardless of age, gender, socio- professional category and possessions (goods) and the majority (84.9%) expressed an interest for purchasing the reengineered Akpan and the reengineered gowe (n=100 consumers) in Benin, which was strongly accepted and more so than the traditional gowe. However, the reengineered Kenkey in Ghana while being comparable acceptance to the traditional white kenkey this would only meet a niche market. However, for the reengineered Kishk Sa'eedi, it was less acceptable and the difference was due to sour taste and spicy flavour. Group 2:The group 2 products had mixed acceptance among consumers. In the case of Kong in and Lanhouin in Senegal, the reengineered products had improved acceptance while for kitoza in Madagascar, there was no improvement in acceptance apart from those in terms of quality and safety. More specifically, Kong made using liquid smoke novel technique (RLK) had by far the highest acceptance and could easily be integrated as part of the Senegalese cuisine. This shows that there is a potential for RLK on the Senegalese market. Two types of reengineered Lanhouin types (Lanhouin dry powder, Lanhouin dry fillet) were greatly acceptable and the powdered form more than the fillet. In the case of Kitoza, consumer acceptance studies showed that there was no significant difference between all samples tested. Group 3: Group 3 reengineered products had mixed acceptance among consumers. Re-engineered bissap (hibiscus drinks) in Senegal were positively appreciated by consumers in Senegal and better accepted than the traditional commercial infusion used as baseline comparison. However, the new drinks were not perceivably different from the baseline drink to consumers concerning both the traditional character and the nutritional and healthy attributes. The reengineered baobab drinks were positively appreciated by consumers in Senegal and significantly better appreciated than the traditional commercial ones earlier tested. Jaabi (Ziziphus mauritiana). The result is the proposition of a reengineered Yaabande presenting fine texture well appreciated by consumers. However, particle size was critical and this needed to be lower than 125μm. Due to this limit, processors have adopted the manual production of flour of particle size 250μm>Ø>125μm, which is less tiresome, though it appears in second rank in the preference of consumers. The detailed methodology for each product is given for Groups I, II and III respectively. Common to all of the methodologies is the Ethical assessment and consent which is listed as follows: Ethical assessment and consent. The studies have been assessed and approved by the University of Greenwich Research Ethics Committee and the Ethics Committee at CIRAD. Consent was sought from sensory panellists and from adult consumers participating in this study. Enumerators informed participants about the study and explained that their participation was entirely voluntary, that they could stop the interview at any point and that the responses would be anonymous

A striking correspondence between the dynamics generated by the vector fields and by the scalar parabolic equations

The purpose of this paper is to enhance a correspondence between the dynamics of the differential equations $\dot y(t)=g(y(t))$ on $\mathbb{R}^d$ and those of the parabolic equations $\dot u=\Delta u +f(x,u,\nabla u)$ on a bounded domain $\Omega$. We give details on the similarities of these dynamics in the cases $d=1$, $d=2$ and $d\geq 3$ and in the corresponding cases $\Omega=(0,1)$, $\Omega=\mathbb{T}^1$ and dim($\Omega$)$\geq 2$ respectively. In addition to the beauty of such a correspondence, this could serve as a guideline for future research on the dynamics of parabolic equations