Influence of the particle shape on the equilibrium morphologies of supracolloidal magnetic filaments

We investigate the equilibrium morphologies of linear and ring-shaped magnetic filaments made from crosslinked ferromagnetic spherical or ellipsoidal colloidal particles. Using Langevin dynamics simulations, we calculate the radius of gyration and total magnetic moment of a single filament at zero field and different temperatures, analyzing the influence of the particles shape, the strength of their magnetic moment and the filament length. Our results show that, among such parameters, the shape of the particles has the strongest qualitative impact on the equilibrium behavior of the filaments

Novel antibodies against RCD-8 as a tool to study processing bodies

Aim. To develop the model system for processing bodies (PBs) state monitoring and accomplish it in the future as a possible read-out of mTOR activity in mammalian cells. Methods. In course of this study we raised polyclonal antibodies against one of the PBs scaffold proteins – RCD-8 and employed cell imaging technique. Results. It has been shown that the obtained antibodies recognize the intracellular structures, namely PBs. The detected protein co-localized with known marker of PBs – DCP1a, and partly with marker of SGs – CPEB. Conclusions. Based on changes of PBs number and size in cells after exposure to known inductors or inhibitors of PB formation we prove the specificity of generated antibodies and possibility of their application for studies on the processing bodies dynamics controlled by mTOR-dependent signalin

Planet Consumption and Stellar Metallicity Enhancements

The evolution of a giant planet within the stellar envelope of a main-sequence star is investigated as a possible mechanism for enhancing the stellar metallicities of the parent stars of extrasolar planetary systems. Three-dimensional hydrodynamical simulations of a planet subject to impacting stellar matter indicate that the envelope of a Jupiter-like giant planet can be completely stripped in the outer stellar convection zone of a solar-mass star. In contrast, Jupiter-like and less massive Saturn-like giant planets are able to survive through the base of the convection zone of a 1.22 solar-mass star. Although strongly dependent on details of planetary interior models, partial or total dissolution of giant planets can result in significant enhancements in the metallicity of host stars with masses between about 1.0 and 1.3 solar masses. The implications of these results with regard to planetary orbital migration are briefly discussed.Comment: 11 pages, 2 figures, accepted for ApJ Letter

Classification of integrable discrete Klein-Gordon models

The Lie algebraic integrability test is applied to the problem of classification of integrable Klein-Gordon type equations on quad-graphs. The list of equations passing the test is presented containing several well-known integrable models. A new integrable example is found, its higher symmetry is presented.Comment: 12 pages, submitted to Physica Script

Synopsis of the tribe Stipeae (Poaceae) in Nepal

Volume: 128Start Page: 97End Page: 11

HCF-2 inhibits cell proliferation and activates differentiation-gene expression programs.

HCF-2 is a member of the host-cell-factor protein family, which arose in early vertebrate evolution as a result of gene duplication. Whereas its paralog, HCF-1, is known to act as a versatile chromatin-associated protein required for cell proliferation and differentiation, much less is known about HCF-2. Here, we show that HCF-2 is broadly present in human and mouse cells, and possesses activities distinct from HCF-1. Unlike HCF-1, which is excluded from nucleoli, HCF-2 is nucleolar-an activity conferred by one and a half C-terminal Fibronectin type 3 repeats and inhibited by the HCF-1 nuclear localization signal. Elevated HCF-2 synthesis in HEK-293 cells results in phenotypes reminiscent of HCF-1-depleted cells, including inhibition of cell proliferation and mitotic defects. Furthermore, increased HCF-2 levels in HEK-293 cells lead to inhibition of cell proliferation and metabolism gene-expression programs with parallel activation of differentiation and morphogenesis gene-expression programs. Thus, the HCF ancestor appears to have evolved into a small two-member protein family possessing contrasting nuclear versus nucleolar localization, and cell proliferation and differentiation functions