5,546 research outputs found

    Outcome Independence of Entanglement in One-Way Computation

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    We show that the various intermediate states appearing in the process of one-way computation at a given step of measurement are all equivalent modulo local unitary transformations. This implies, in particular, that all those intermediate states share the same entanglement irrespective of the measurement outcomes, indicating that the process of one-way computation is essentially unique with respect to local quantum operations.Comment: 6 pages, 4 figure

    Neutrino mass constraint from CMB and its degeneracy with other cosmological parameters

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    We show that the cosmic microwave background (CMB) data of WMAP can give subelectronvolt limit on the neutrino mass: m_nu < 0.63 eV (95% CL). We also investigate its degeneracy with other cosmological parameters. In particular, we show the Hubble constant derived from the WMAP data decreases considerably when the neutrino mass is a few times 0.1 eV.Comment: 3 pages, 2 figures, prepared for the TAUP2007 Proceeding

    Autoimmune hyperphosphatemic tumoral calcinosis in a patient with FGF23 autoantibodies

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    Hyperphosphatemic familial tumoral calcinosis (HFTC)/hyperostosis-hyperphosphatemia syndrome (HHS) is an autosomal recessive disorder of ectopic calcification due to deficiency of or resistance to intact fibroblast growth factor 23 (iFGF23). Inactivating mutations in FGF23, N-acetylgalactosaminyltransferase 3 (GALNT3), or KLOTHO (KL) have been reported as causing HFTC/HHS. We present what we believe is the first identified case of autoimmune hyperphosphatemic tumoral calcinosis in an 8-year-old boy. In addition to the classical clinical and biochemical features of hyperphosphatemic tumoral calcinosis, the patient exhibited markedly elevated intact and C-terminal FGF23 levels, suggestive of FGF23 resistance. However, no mutations in FGF23, KL, or FGF receptor 1 (FGFR1) were identified. He subsequently developed type 1 diabetes mellitus, which raised the possibility of an autoimmune cause for hyperphosphatemic tumoral calcinosis. Luciferase immunoprecipitation systems revealed markedly elevated FGF23 autoantibodies without detectable FGFR1 or Klotho autoantibodies. Using an in vitro FGF23 functional assay, we found that the FGF23 autoantibodies in the patient's plasma blocked downstream signaling via the MAPK/ERK signaling pathway in a dose-dependent manner. Thus, this report describes the first case, to our knowledge, of autoimmune hyperphosphatemic tumoral calcinosis with pathogenic autoantibodies targeting FGF23. Identification of this pathophysiology extends the etiologic spectrum of hyperphosphatemic tumoral calcinosis and suggests that immunomodulatory therapy may be an effective treatment

    An Analysis of the Quantum Penny Flip Game using Geometric Algebra

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    We analyze the quantum penny flip game using geometric algebra and so determine all possible unitary transformations which enable the player Q to implement a winning strategy. Geometric algebra provides a clear visual picture of the quantum game and its strategies, as well as providing a simple and direct derivation of the winning transformation, which we demonstrate can be parametrized by two angles. For comparison we derive the same general winning strategy by conventional means using density matrices.Comment: 8 Pages, 1 Figure, accepted for publication in the Journal of Physical Society of Japa

    The oscillation effects on thermalization of the neutrinos in the universe with low reheating temperature

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    We study how the oscillations of the neutrinos affect their thermalization process during the reheating period with temperature O(1) MeV in the early universe. We follow the evolution of the neutrino density matrices and investigate how the predictions of big bang nucleosynthesis vary with the reheating temperature. For the reheating temperature of several MeV, we find that including the oscillations makes different predictions, especially for 4^4He abundance. Also, the effects on the lower bound of the reheating temperature from cosmological observations are discussed.Comment: 24 pages, 8 figures; references and explanatory comments added, conclusion unchange

    Spatial chaos and complexity in the intracellular space of cancer and normal cells

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    BACKGROUND: One of the most challenging problems in biological image analysis is the quantification of the dynamical mechanism and complexity of the intracellular space. This paper investigates potential spatial chaos and complex behavior of the intracellular space of typical cancer and normal cell images whose structural details are revealed by the combination of scanning electron microscopy and focused ion beam systems. Such numerical quantifications have important implications for computer modeling and simulation of diseases. METHODS: Cancer cell lines derived from a human head and neck squamous cell carcinoma (SCC-61) and normal mouse embryonic fibroblast (MEF) cells produced by focused ion beam scanning electron microscopes were used in this study. Spatial distributions of the organelles of cancer and normal cells can be analyzed at both short range and long range of the bounded dynamical system of the image space, depending on the orientations of the spatial cell. A procedure was designed for calculating the largest Lyapunov exponent, which is an indicator of the potential chaotic behavior in intracellular images. Furthermore, the sample entropy and regularity dimension were applied to measure the complexity of the intracellular images. RESULTS: Positive values of the largest Lyapunov exponents (LLEs) of the intracellular space of the SCC-61 were obtained in different spatial orientations for both long-range and short-range models, suggesting the chaotic behavior of the cell. The MEF has smaller positive values of LLEs in the long range than those of the SCC-61, and zero vales of the LLEs in the short range analysis, suggesting a non-chaotic behavior. The intracellular space of the SCC-61 is found to be more complex than that of the MEF. The degree of complexity measured in the spatial distribution of the intracellular space in the diagonal direction was found to be approximately twice larger than the complexity measured in the horizontal and vertical directions. CONCLUSION: Initial findings are promising for characterizing different types of cells and therefore useful for studying cancer cells in the spatial domain using state-of-the-art imaging technology. The measures of the chaotic behavior and complexity of the spatial cell will help computational biologists gain insights into identifying associations between the oscillation patterns and spatial parameters of cells, and appropriate model for simulating cancer cell signaling networks for cancer treatment and new drug discovery

    Entanglement Measures for Intermediate Separability of Quantum States

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    We present a family of entanglement measures R_m which act as indicators for separability of n-qubit quantum states into m subsystems for arbitrary 2 \leq m \leq n. The measure R_m vanishes if the state is separable into m subsystems, and for m = n it gives the Meyer-Wallach measure while for m = 2 it reduces, in effect, to the one introduced recently by Love et al. The measures R_m are evaluated explicitly for the GHZ state and the W state (and its modifications, the W_k states) to show that these globally entangled states exhibit rather distinct behaviors under the measures, indicating the utility of the measures R_m for characterizing globally entangled states as well.Comment: 8 pages, 8 figure

    The Kepler Light Curve of V344 Lyrae: Constraining the Thermal-Viscous Limit Cycle Instability

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    We present time dependent modeling based on the accretion disk limit cycle model for a 270 d light curve of the short period SU UMa-type dwarf nova V344 Lyr taken by Kepler. The unprecedented precision and cadence (1 minute) far surpass that generally available for long term light curves. The data encompass two superoutbursts and 17 normal (i.e., short) outbursts. The main decay of the superoutbursts is nearly perfectly exponential, decaying at a rate ~12 d/mag, while the much more rapid decays of the normal outbursts exhibit a faster-than-exponential shape. Our modeling using the basic accretion disk limit cycle can produce the main features of the V344 Lyr light curve, including the peak outburst brightness. Nevertheless there are obvious deficiencies in our model light curves: (1) The rise times we calculate, both for the normal and superoutbursts, are too fast. (2) The superoutbursts are too short. (3) The shoulders on the rise to superoutburst have more structure than the shoulder in the observed superoutburst and are too slow, comprising about a third to half of the total viscous plateau, rather than the ~10% observed. However, one of the alpha_{cold} -> alpha_{hot} interpolation schemes we investigate (one that is physically motivated) does yield longer superoutbursts with suitably short, less structured shoulders.Comment: 39 pages, 9 figures, accepted in the Astrophysical Journa

    CDW Ordering in Stripe Phase of Underdoped Cuprates

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    The in-plane resistivity and out-of-plane resistivity of non-superconducting RBCO (R = Y, Tm) and Fe-doped Bi2212 single crystals are discussed. The comparison of electrical transport properties of the cuprates and quasi-one dimensional (1D) (TMTSF)2PF6 organic conductor suggests that RBCO and Bi2212 exhibit 1D transport properties, and the step rise at low temperatures in the resistivities of the cuprates and quasi-1D organic conductor is due to charge-density-wave ordering. We discuss also phonon-electron interactions in cuprates at low temperatures.Comment: 10 pages including 4 figure
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