Developmental contexts and features of elite academy football players: Coach and player perspectives

Player profiling can reap many benefits; through reflective coach-athlete dialogue that produces a profile the athlete has a raised awareness of their own development, while the coach has an opportunity to understand the athlete's viewpoint. In this study, we explored how coaches and players perceived the development features of an elite academy footballer and the contexts in which these features are revealed, in order to develop a player profile to be used for mentoring players. Using a Delphi polling technique, coaches and players experienced a number of 'rounds' of expressing their opinions regarding player development contexts and features, ultimately reduced into a consensus. Players and coaches had differing priorities on the key contexts of player development. These contexts, when they reflect the consensus between players and coaches were heavily dominated by ability within the game and training. Personal, social, school, and lifestyle contexts featured less prominently. Although 'discipline' was frequently mentioned as an important player development feature, coaches and players disagreed on the importance of 'training'

COPD patients hospitalized with exacerbations have greater cognitive impairment than patients hospitalized with decompensated heart failure

Purpose: People with COPD have cognitive dysfunction, which is greater in those hospitalized for exacerbations than in stable outpatients. We tested the hypothesis that cognitive dysfunction at exacerbation is a disease-specific feature of COPD, rather than a nonspecific feature of hospitalization for acute illness, by comparing cognition between patients hospitalized for acute COPD exacerbations and those with worsening heart failure (HF). Patients and methods: A total of 40 hospital inpatients were recruited, 20 patients with COPD exacerbations and 20 patients with congestive or left-sided HF. Exclusion criteria included previous stroke, known neurological disease, and marked alcohol excess. Participants completed the Montreal cognitive assessment (MoCA) and Hospital Anxiety and Depression Scale (HADS) and underwent spirometry and review of clinical records. Results: Age (mean±SD, COPD 73±10; HF 76±11 years), acute illness severity (Acute Physiology and Chronic Health Evaluation [APACHE]-II, COPD 15.4±3.5; HF 15.9±3.0), comorbidities (Charlson index, COPD 1.3±1.9; HF 1.6±1.5), and educational background were similar between COPD and HF groups. MoCA total was significantly lower in COPD than in HF (COPD 20.6±5.6; HF 24.8±3.5, P=0.007); however, significance was lost after correction for age, sex, and pack year smoking history. When compared with HF patients, the COPD cohort performed worse on the following domains of the MoCA: visuospatial function (median [IQR], COPD 0 [1]; HF 2 [1], P=0.003), executive function (COPD 2 [1]; HF 3 [1], P=0.035), and attention (COPD 4 [3]; HF 6 [2], P=0.020). Age (P=0.012) and random glucose concentration (P=0.041) were associated with cognitive function in whole group analysis, with pack year smoking history reaching borderline significance (P=0.050). Conclusion: Total MoCA score for COPD and HF indicated that both groups had mild cognitive impairment, although this was greater in people with COPD. Mechanisms underlying the observed cognitive dysfunction in COPD remain unclear but appear related to blood glucose concentrations and greater lifetime smoking load

Fate of drugs during wastewater treatment

This is the post-print version of the final paper published in TrAC Trends in Analytical Chemistry. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. Copyright @ 2013 Elsevier B.V.Recent trends in the determination of pharmaceutical drugs in wastewaters focus on the development of rapid multi-residue methods. This review addresses recent analytical trends in drug determination in environmental matrices used to facilitate fate studies. Analytical requirements for further fate evaluation and tertiary process selection and optimization are also discussed.EPSRC, Northumbrian Water, Anglian Water, Severn Trent Water, Yorkshire Water, and United Utilities

Anthropometric and Physical Profiles of English Academy Rugby Union Players.

The purpose of the present study was to evaluate the anthropometric and physical characteristics of English regional academy rugby union academy players by age category (under 16, under 18 and under 21s). Data were collected on 67 academy players at the beginning of the pre-season period and comprised anthropometric (height, body mass and sum of 8 skinfolds) and physical (5 m, 10 m, 20 m & 40 m sprint, acceleration, velocity & momentum; agility 505; vertical jump; yo-yo intermittent recovery test level 1; 30-15 Intermittent Fitness Test; absolute and relative 3 repetition maximum (3RM) front squat, split squat, bench press, prone row and chin; and isometric mid-thigh pull). One way analysis of variance demonstrated significant increases across the three age categories (p < 0.05) for height (e.g., 16s = 178.8 ± 7.1; 18s = 183.5 ± 7.2; 21s = 186.7 ± 6.61 cm), body mass (e.g., 16s = 79.4 ± 12.8; 18s = 88.3 ± 11.9; 21s = 98.3 ± 10.4kg), countermovement jump height and peak power, sprint momentum, velocity and acceleration; absolute, relative and isometric (e.g., 16s = 2157.9 ± 309.9; 18s = 2561.3 ± 339.4; 21s = 3104.5 ± 354.0 N) strength. Momentum, maximal speed and the ability to maintain acceleration were all discriminating factors between age categories, suggesting that these variables may be more important to monitor rather than sprint times. These findings highlight that anthropometric and physical characteristics develop across age categories and provide comparative data for English academy Rugby Union players

Detection of Cosmic Microwave Background Structure in a Second Field with the Cosmic Anisotropy Telescope

We describe observations at frequencies near 15 GHz of the second 2x2 degree field imaged with the Cambridge Cosmic Anisotropy Telescope (CAT). After the removal of discrete radio sources, structure is detected in the images on characteristic scales of about half a degree, corresponding to spherical harmonic multipoles in the approximate range l= 330--680. A Bayesian analysis confirms that the signal arises predominantly from the cosmic microwave background (CMB) radiation for multipoles in the lower half of this range; the average broad-band power in a bin with centroid l=422 (theta = 51') is estimated to be Delta_T/T=2.1^{+0.4}_{-0.5} x 10^{-5}. For multipoles centred on l=615 (theta =35'), we find contamination from Galactic emission is significant, and constrain the CMB contribution to the measured power in this bin to be Delta_T/T <2.0 x 10^{-5} (1-sigma upper limit). These new results are consistent with the first detection made by CAT in a completely different area of sky. Together with data from other experiments, this new CAT detection adds weight to earlier evidence from CAT for a downturn in the CMB power spectrum on scales smaller than 1 degree. Improved limits on the values of H_0 and Omega are determined using the new CAT data.Comment: 5 pages, 5 figures (gif), submitted to MNRA

Comprehensive Solution to the Cosmological Constant, Zero-Point Energy, and Quantum Gravity Problems

We present a solution to the cosmological constant, the zero-point energy, and the quantum gravity problems within a single comprehensive framework. We show that in quantum theories of gravity in which the zero-point energy density of the gravitational field is well-defined, the cosmological constant and zero-point energy problems solve each other by mutual cancellation between the cosmological constant and the matter and gravitational field zero-point energy densities. Because of this cancellation, regulation of the matter field zero-point energy density is not needed, and thus does not cause any trace anomaly to arise. We exhibit our results in two theories of gravity that are well-defined quantum-mechanically. Both of these theories are locally conformal invariant, quantum Einstein gravity in two dimensions and Weyl-tensor-based quantum conformal gravity in four dimensions (a fourth-order derivative quantum theory of the type that Bender and Mannheim have recently shown to be ghost-free and unitary). Central to our approach is the requirement that any and all departures of the geometry from Minkowski are to be brought about by quantum mechanics alone. Consequently, there have to be no fundamental classical fields, and all mass scales have to be generated by dynamical condensates. In such a situation the trace of the matter field energy-momentum tensor is zero, a constraint that obliges its cosmological constant and zero-point contributions to cancel each other identically, no matter how large they might be. Quantization of the gravitational field is caused by its coupling to quantized matter fields, with the gravitational field not needing any independent quantization of its own. With there being no a priori classical curvature, one does not have to make it compatible with quantization.Comment: Final version, to appear in General Relativity and Gravitation (the final publication is available at http://www.springerlink.com). 58 pages, revtex4, some additions to text and some added reference

Benefits of robotic cystectomy with intracorporeal diversion for patients with low cardiorespiratory fitness: A prospective cohort study

BACKGROUND: Patients undergoing radical cystectomy have associated comorbidities resulting in reduced cardiorespiratory fitness. Preoperative cardiopulmonary exercise testing (CPET) measures including anaerobic threshold (AT) can predict major adverse events (MAE) and hospital length of stay (LOS) for patients undergoing open and robotic cystectomy with extracorporeal diversion. Our objective was to determine the relationship between CPET measures and outcome in patients undergoing robotic radical cystectomy and intracorporeal diversion (intracorporeal robotic assisted radical cystectomy [iRARC]). METHODS: A single institution prospective cohort study in patients undergoing iRARC for muscle invasive and high-grade bladder cancer. Inclusion: patients undergoing standardised CPET before iRARC. Exclusions: patients not consenting to data collection. Data on CPET measures (AT, ventilatory equivalent for carbon dioxide [VE/VCO2] at AT, peak oxygen uptake [VO2]), and patient demographics prospectively collected. Outcome measurements included hospital LOS; 30-day MAE and 90-day mortality data, which were prospectively recorded. Descriptive and regression analyses were used to assess whether CPET measures were associated with or predicted outcomes. RESULTS: From June 2011 to March 2015, 128 patients underwent radical cystectomy (open cystectomy, n = 17; iRARC, n = 111). A total of 82 patients who underwent iRARC and CPET and consented to participation were included. Median (interquartile range): age = 65 (58–73); body mass index = 27 (23–30); AT = 10.0 (9–11), Peak VO2 = 15.0 (13–18.5), VE/VCO2 (AT) = 33.0 (30–38). 30-day MAE = 14/111 (12.6%): death = 2, multiorgan failure = 2, abscess = 2, gastrointestinal = 2, renal = 6; 90-day mortality = 3/111 (2.7%). AT, peak VO2, and VE/VCO2 (at AT) were not significant predictors of 30-day MAE or LOS. The results are limited by the absence of control group undergoing open surgery. CONCLUSIONS: Poor cardiorespiratory fitness does not predict increased hospital LOS or MAEs in patients undergoing iRARC. Overall, MAE and LOS comparable with other series

Induced measures in the space of mixed quantum states

We analyze several product measures in the space of mixed quantum states. In particular we study measures induced by the operation of partial tracing. The natural, rotationally invariant measure on the set of all pure states of a N x K composite system, induces a unique measure in the space of N x N mixed states (or in the space of K x K mixed states, if the reduction takes place with respect to the first subsystem). For K=N the induced measure is equal to the Hilbert-Schmidt measure, which is shown to coincide with the measure induced by singular values of non-Hermitian random Gaussian matrices pertaining to the Ginibre ensemble. We compute several averages with respect to this measure and show that the mean entanglement of $N \times N$ pure states behaves as lnN-1/2.Comment: 12 latex pages, 2 figures in epsf, submited to J. Phys. A. ver.3, some improvements and a few references adde

Access to interpreting services in England: secondary analysis of national data

Background: Overcoming language barriers to health care is a global challenge. There is great linguistic diversity in the major cities in the UK with more than 300 languages, excluding dialects, spoken by children in London alone. However, there is dearth of data on the number of non-English speakers for planning effective interpreting services. The aim was to estimate the number of people requiring language support amongst the minority ethnic communities in England. Methods: Secondary analysis of national representative sample of subjects recruited to the Health Surveys for England 1999 and 2004. Results: 298,432 individuals from the four main minority ethnic communities (Indian, Pakistani, Bangladeshi and Chinese) who may be unable to communicate effectively with a health professional. This represents 2,520,885 general practice consultations per year where interpreting services might be required. Conclusion: Effective interpreting services are required to improve access and health outcomes of non-English speakers and thereby facilitate a reduction in health inequalities