Jumping bristletail (Insecta: Apterygota: Microcoryphia) records in the southeastern United States

Few records of Microcoryphia exist for the southeastern United States, with named species being reported only from Arkansas, Tennessee, and the mid-Atlantic states, and with an unnamed species being reported from Georgia. Records are here provided from 291 specimens housed in the Mississippi Entomological Museum, including ten new species-level state records. This is also the first published report of the order Microcoryphia from Alabama and Mississippi. Species include the machilids Pedetontoides atlanticus Mendes in Alabama, Arkansas, Georgia, Mississippi, and North Carolina; Pedetontus cf. atlanticus in Kentucky; Pedetontus (Verhoeffilis) gershneri Allen in Arkansas; and Pedetontus (Pedetontus) saltator Wygodzinsky and Schmidt in Mississippi and North Carolina; and the meinertellid Machiloides banksi (Silvestri) in Alabama, Arkansas, Mississippi, and North Carolina

Dynamics of rapidly rotating Bose-Einstein condensates in a harmonic plus quartic trap

A two-dimensional rapidly rotating Bose-Einstein condensate in a harmonic plus quartic trap is expected to have unusual vortex states that do not occur in a pure harmonic trap. At a critical rotation speed $\Omega_h$, a central hole appears in the condensate, and at some faster rotation speed $\Omega_g$, the system undergoes a transition to a giant vortex state with pure irrotational flow. Using a time-dependent variational analysis, we study the behavior of an annular condensate with a single concentric ring of vortices. The transition to a giant vortex state is investigated by comparing the energy of the two equilibrium states (the ring of vortices and the giant vortex) and also by studying the dynamical stability of small excitation modes of the ring of vortices.Comment: 12pages, 4figure

Probabilities of spurious connections in gene networks: Application to expression time series

Motivation: The reconstruction of gene networks from gene expression microarrays is gaining popularity as methods improve and as more data become available. The reliability of such networks could be judged by the probability that a connection between genes is spurious, resulting from chance fluctuations rather than from a true biological relationship. Results: Unlike the false discovery rate and positive false discovery rate, the decisive false discovery rate (dFDR) is exactly equal to a conditional probability without assuming independence or the randomness of hypothesis truth values. This property is useful not only in the common application to the detection of differential gene expression, but also in determining the probability of a spurious connection in a reconstructed gene network. Estimators of the dFDR can estimate each of three probabilities: 1. The probability that two genes that appear to be associated with each other lack such association. 2. The probability that a time ordering observed for two associated genes is misleading. 3. The probability that a time ordering observed for two genes is misleading, either because they are not associated or because they are associated without a lag in time. The first probability applies to both static and dynamic gene networks, and the other two only apply to dynamic gene networks. Availability: Cross-platform software for network reconstruction, probability estimation, and plotting is free from http://www.davidbickel.com as R functions and a Java application.Comment: Like q-bio.GN/0404032, this was rejected in March 2004 because it was submitted to the math archive. The only modification is a corrected reference to q-bio.GN/0404032, which was not modified at al

Within- and between-pen transmission of Classical Swine Fever Virus: a new method to estimate the basic reproduction ratio from transmission experiments

We present a method to estimate basic reproduction ratio R0 from transmission experiments. By using previously published data of experiments with Classical Swine Fever Virus more extensively, we obtained smaller confidence intervals than the martingale method used in the original papers. Moreover, our method allows simultaneous estimation of a reproduction ratio within pens R0w and a modified reproduction ratio between pens R'0b. Resulting estimates of R0w and R'0b for weaner pigs were 100 (95% CI 54.4-186) and 7.77 (4.68-12.9), respectively. For slaughter pigs they were 15.5 (6.20-38.7) and 3.39 (1.54-7.45), respectively. We believe, because of the smaller confidence intervals we were able to obtain, that the method presented here is better suited for use in future experiments

The Trouble with Hubble Types in the Virgo Cluster

Quantitative measures of central light concentration and star formation activity are derived from R and Halpha surface photometry of 84 bright S0-Scd Virgo Cluster and isolated spiral galaxies. For isolated spirals, there is a good correlation between these two parameters and assigned Hubble types. In the Virgo Cluster, the correlation between central light concentration and star formation activity is significantly weaker. Virgo Cluster spirals have systematically reduced global star formation with respect to isolated spirals, with severe reduction in the outer disk, but normal or enhanced activity in the inner disk. Assigned Hubble types are thus inadequate to describe the range in morphologies of bright Virgo Cluster spirals. In particular, spirals with reduced global star formation activity are often assigned misleading early-type classifications, irrespective of their central light concentrations. 45+-25% of the galaxies classified as Sa in the Virgo Cluster sample have central light concentrations more characteristic of isolated Sb-Sc galaxies. The misleading classification of low concentration galaxies with low star formation rates as early-type spirals may account for part of the excess of `early-type' spiral galaxies in clusters. Thus the morphology-density relationship is not all due to a systematic increase in the bulge-to-disk ratio with environmental density.Comment: Accepted for publication in ApJ Letters. Latex aaspp4.sty, 9 pages, 2 Postscript (embedded) figures. Also available at http://www.astro.yale.edu/koopmann/preprint.htm

Quality of Radiomic Features in Glioblastoma Multiforme: Impact of Semi-Automated Tumor Segmentation Software.

ObjectiveThe purpose of this study was to evaluate the reliability and quality of radiomic features in glioblastoma multiforme (GBM) derived from tumor volumes obtained with semi-automated tumor segmentation software.Materials and methodsMR images of 45 GBM patients (29 males, 16 females) were downloaded from The Cancer Imaging Archive, in which post-contrast T1-weighted imaging and fluid-attenuated inversion recovery MR sequences were used. Two raters independently segmented the tumors using two semi-automated segmentation tools (TumorPrism3D and 3D Slicer). Regions of interest corresponding to contrast-enhancing lesion, necrotic portions, and non-enhancing T2 high signal intensity component were segmented for each tumor. A total of 180 imaging features were extracted, and their quality was evaluated in terms of stability, normalized dynamic range (NDR), and redundancy, using intra-class correlation coefficients, cluster consensus, and Rand Statistic.ResultsOur study results showed that most of the radiomic features in GBM were highly stable. Over 90% of 180 features showed good stability (intra-class correlation coefficient [ICC] ≥ 0.8), whereas only 7 features were of poor stability (ICC < 0.5). Most first order statistics and morphometric features showed moderate-to-high NDR (4 > NDR ≥1), while above 35% of the texture features showed poor NDR (< 1). Features were shown to cluster into only 5 groups, indicating that they were highly redundant.ConclusionThe use of semi-automated software tools provided sufficiently reliable tumor segmentation and feature stability; thus helping to overcome the inherent inter-rater and intra-rater variability of user intervention. However, certain aspects of feature quality, including NDR and redundancy, need to be assessed for determination of representative signature features before further development of radiomics

Interferometry using spatial adiabatic passage in quantum dot networks

We show that techniques of spatial adiabatic passage can be used to realise an electron interferometer in a geometry analogous to a conventional Aharonov-Bohm ring, with transport of the particle through the device modulated using coherent transport adiabatic passage. This device shows an interesting interplay between the adiabatic and non-adiabatic behaviour of the system. The transition between non-adiabatic and adiabatic behaviour may be tuned via system parameters and the total time over which the protocol is enacted. Interference effects in the final state populations analogous to the electrostatic Aharonov-Bohm effect are observed.Comment: Version accepted in Phys. Rev. B, 8 pages, 6 figure

RNA under Tension: Folding Landscapes, Kinetic Partitioning Mechanism, and Molecular Tensegrity

Non-coding RNA sequences play a great role in controlling a number of cellular functions, thus raising the need to understand their complex conformational dynamics in quantitative detail. In this perspective, we first show that single molecule pulling experiments when combined with with theory and simulations can be used to quantitatively explore the folding landscape of nucleic acid hairpins, and riboswitches with tertiary interactions. Applications to riboswitches, which are non-coding RNA elements that control gene expression by undergoing dynamical conformational changes in response to binding of metabolites, lead to an organization principle that assembly of RNA is determined by the stability of isolated helices. We also point out the limitations of single molecule pulling experiments, with molecular extension as the only accessible parameter, in extracting key parameters of the folding landscapes of RNA molecules.Comment: 24 pages, 6 figure