Towards a clinical trial ontology using a concern-oriented approach

Not yet availablePer ridurre i costi e migliorare la qualita\u27 della ricerca nei trial clinici (CT) e\u27 necessario un approccio piu\u27 sistematico all\u27automazione dei CT per rinforzare l\u27interoperabilita\u27 a vari livelli del processo di ricerca. Per questo scopo e\u27 stato sviluppato un modello concettuale di CT. Alla base di ogni approccio di modellizzazione ci sono criteri di partizione che ci permettono di dominare la complessita\u27 dell\u27universo da modellare. In questo rapporto noi introduciamo un metodo originale di analisi basato sui concern degli stakeholder per partizionare il domino concettuale dei CT in sotto-domini orientati agli stakeholder. Le rappresentazioni mentali degli stakeholder relative a ciascun concern sono identificati come cluster di concetti collegati ad altri concetti. Noi consideriamo ciascun cluster come una base razionale per il relativo concern. I concetti trovati nelle basi razionali popolano l\u27universo del discorso specifico per ogni stakeholder e compongono il vocabolario degli stakeholder. Alcuni concetti sono condivisi con altri stakeholder, mentre altri sono specifici di uno stakehoder; alcuni concetti sono specifici dei CT, mentre altri sono concetti medici o generali. In questo modo un\u27ontologia orientata ai concern per i CT puo\u27 essere creata. Il metodo e\u27 illustrato utilizzando i criteri di selezione dei soggetti, una componente di un progetto di CT, ma puo\u27 essere usato per ogni altra componente del protocollo del CT. La tassonomia del vocabolario dei concetti dei CT e la rete delle relative basi razionali ci fornisce una struttura possibile per lo sviluppo del software specialmente se si adotta una soluzione basata su architetture orientate ai servizi

The survey and mapping of sand-boil landforms related to the Emilia 2012 earthquakes: preliminary results.

Sand boils, which are also known as sand blows or sand volcanoes, are among the most common superficial effects induced by high-magnitude earthquakes. These generally occur in or close to alluvial plains when a strong earthquake (M >5) strikes on a lens of saturated and unconsolidated sand deposits that are constrained between silt-clay layers, where the sediments are converted into a fluid suspension. The liquefaction phenomena requires the presence of saturated and uncompacted sand, and a groundwater table near the ground surface. This geological–geomorphological setting is common and widespread for the Po Plain (Italy). The Po Plain (ca. 46,000 km2) represents 15% of the Italian territory. It hosts a population of about 20 million people (mean density of 450 people/km2) and many infrastructures. Thus, the Po Plain is an area of high vulnerability when considering the liquefaction potential in the case of a strong earthquake. Despite the potential, such phenomena are rarely observed in northern Italy, because strong earthquakes are not frequent in this region; e.g., historical data report soil liquefaction near Ferrara in 1570 (M 5.3) and in Argenta 1624 (M 5.5). In the Emilia quakes of May 20 and 29, 2012, the most widespread coseismic effects were soil liquefaction and ground cracks, which occurred over wide areas in the Provinces of Modena, Ferrara, Bologna, Reggio Emilia and Mantov

The survey and mapping of sand-boil landforms related to the Emilia 2012 earthquakes: preliminary results.

Sand boils, which are also known as sand blows or sand volcanoes, are among the most common superficial effects induced by high-magnitude earthquakes. These generally occur in or close to alluvial plains when a strong earthquake (M >5) strikes on a lens of saturated and unconsolidated sand deposits that are constrained between silt-clay layers, where the sediments are converted into a fluid suspension. The liquefaction phenomena requires the presence of saturated and uncompacted sand, and a groundwater table near the ground surface. This geological\u2013geomorphological setting is common and widespread for the Po Plain (Italy). The Po Plain (ca. 46,000 km2) represents 15% of the Italian territory. It hosts a population of about 20 million people (mean density of 450 people/km2) and many infrastructures. Thus, the Po Plain is an area of high vulnerability when considering the liquefaction potential in the case of a strong earthquake. Despite the potential, such phenomena are rarely observed in northern Italy, because strong earthquakes are not frequent in this region; e.g., historical data report soil liquefaction near Ferrara in 1570 (M 5.3) and in Argenta 1624 (M 5.5). In the Emilia quakes of May 20 and 29, 2012, the most widespread coseismic effects were soil liquefaction and ground cracks, which occurred over wide areas in the Provinces of Modena, Ferrara, Bologna, Reggio Emilia and Mantov