43 research outputs found

    Predictive Uncertainty-based Bias Mitigation in Ranking

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    Societal biases that are contained in retrieved documents have received increased interest. Such biases, which are often prevalent in the training data and learned by the model, can cause societal harms, by misrepresenting certain groups, and by enforcing stereotypes. Mitigating such biases demands algorithms that balance the trade-off between maximized utility for the user with fairness objectives, which incentivize unbiased rankings. Prior work on bias mitigation often assumes that ranking scores, which correspond to the utility that a document holds for a user, can be accurately determined. In reality, there is always a degree of uncertainty in the estimate of expected document utility. This uncertainty can be approximated by viewing ranking models through a Bayesian perspective, where the standard deterministic score becomes a distribution. In this work, we investigate whether uncertainty estimates can be used to decrease the amount of bias in the ranked results, while minimizing loss in measured utility. We introduce a simple method that uses the uncertainty of the ranking scores for an uncertainty-aware, post hoc approach to bias mitigation. We compare our proposed method with existing baselines for bias mitigation with respect to the utility-fairness trade-off, the controllability of methods, and computational costs. We show that an uncertainty-based approach can provide an intuitive and flexible trade-off that outperforms all baselines without additional training requirements, allowing for the post hoc use of this approach on top of arbitrary retrieval models

    Mechanical properties of sandwich panels constructed from polystyrene/cement mixed cores and thin cement sheet facings

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    © 2015, © The Author(s) 2015. Sandwich panels are made of two materials that are relatively weak in their separated state, but are improved when they are constructed together in a sandwich panel. Sandwich panels can be used for almost any section of a building including roofs, walls and floors. These building components are regularly required to provide insulation properties, weatherproofing properties and durability in addition to providing structural load bearing characteristics. Polystyrene/cement mixed cores and thin cement sheet facings sandwich panels are Australian products made of cement-polystyrene beaded mixture encapsulated between two thick cement board sheets. The structural properties of sandwich panels constructed of polystyrene/cement cores and thin cement sheet facings are relatively unknown. Therefore, in this study, to understand the mechanical behaviour and properties of those sandwich panels, a series of experimental tests have been performed and the outcomes have been explained and discussed. Based on the results of this study, values for modulus of elasticity and ultimate strength of the sandwich panels in dry and saturated conditions have been determined and proposed for practical applications

    Age and Sex in the Development of Hepatic Encephalopathy: Role of Alcohol

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    Hepatic encephalopathy (HE) is a neurological condition linked to liver failure. Acute HE (Type A) occurs with acute liver failure, while chronic HE (Type C) is tied to cirrhosis and portal hypertension. HE treatments lag due to gaps in understanding its development by gender and age. We studied how sex and age impact HE and its severity with combined liver toxins. Our findings indicate that drug-induced (thioacetamide, TAA) brain edema was more severe in aged males than in young males or young/aged female rats. However, adding alcohol (ethanol, EtOH) worsens TAA’s brain edema in both young and aged females, with females experiencing a more severe effect than males. These patterns also apply to Type A HE induced by azoxymethane (AZO) in mice. Similarly, TAA-induced behavioral deficits in Type C HE were milder in young and aged females than in males. Conversely, EtOH and TAA in young/aged males led to severe brain edema and fatality without noticeable behavioral changes. TAA metabolism was slower in aged males than in young or middle-aged rats. When TAA-treated aged male rats received EtOH, there was a slow and sustained plasma level of thioacetamide sulfoxide (TASO). This suggests that with EtOH, TAA-induced HE is more severe in aged males. TAA metabolism was similar in young, middle-aged, and aged female rats. However, with EtOH, young and aged females experience more severe drug-induced HE as compared to middle-aged adult rats. These findings strongly suggest that gender and age play a role in the severity of HE development and that the presence of one or more liver toxins may aggravate the severity of the disease progression

    Standardized multidisciplinary evaluation yields significant previously undiagnosed morbidity in adult women with Turner syndrome

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    Contains fulltext : 96365.pdf (publisher's version ) (Open Access)CONTEXT: Besides short stature and gonadal dysgenesis, Turner syndrome (TS) is associated with various abnormalities. Adults with TS have a reduced life expectancy, mainly related to structural abnormalities of the heart and aorta, and an increased risk of atherosclerosis. OBJECTIVE: Our objective was to investigate the yield of an initial standardized multidisciplinary screening in adult TS patients. DESIGN AND SETTING: This was an observational study at a multidisciplinary care unit for adult women with TS. PARTICIPANTS: Participants were adult women with TS (n = 150). Mean age was 31.0 +/- 10.4 yr, with 47% karyotype 45,X. INTERVENTIONS: All women were consulted by an endocrinologist, a gynecologist, a cardiologist, an otorhinolaryngologist, and when indicated, a psychologist. The screening included magnetic resonance imaging of the heart and aorta, echocardiography, electrocardiogram, dual-energy x-ray absorptiometry, renal ultrasound, audiogram, and laboratory investigations according to international expert recommendations. MAIN OUTCOME MEASURES: New diagnoses and prevalence of TS-associated morbidity were evaluated. RESULTS: Thirty percent of patients currently lacked medical follow-up, and 15% lacked estrogen replacement therapy in the recent last years. The following disorders were newly diagnosed: bicuspid aortic valve (n = 13), coarctation of the aorta (n = 9), elongation of the transverse aortic arch (n = 27), dilation of the aorta (n = 34), osteoporosis (n = 8), osteopenia (n = 56), renal abnormalities (n = 7), subclinical hypothyroidism (n = 33), celiac disease (n = 3), glucose intolerance (n = 12), dyslipidemia (n = 52), hypertension (n = 39), and hearing loss warranting a hearing aid (n = 8). Psychological consultation was needed in 23 cases. CONCLUSIONS: Standardized multidisciplinary evaluation of adult women with TS as advocated by expert opinion is effective and identifies significant morbidity. Girls with TS benefit from a careful transition to ongoing adult medical care
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