5,875 research outputs found

    Monitoring cardiovascular function in the primate under prolonged weightlessness

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    Monitoring cardiovascular function in primates under prolonged weightlessnes

    Modularization for the Cell Ontology

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    One of the premises of the OBO Foundry is that development of an orthogonal set of ontologies will increase domain expert contributions and logical interoperability, and decrease maintenance workload. For these reasons, the Cell Ontology (CL) is being re-engineered. This process requires the extraction of sub-modules from existing OBO ontologies, which presents a number of practical engineering challenges. These extracted modules may be intended to cover a narrow or a broad set of species. In addition, applications and resources that make use of the Cell Ontology have particular modularization requirements, such as the ability to extract custom subsets or unions of the Cell Ontology with other OBO ontologies. These extracted modules may be intended to cover a narrow or a broad set of species, which presents unique complications.

We discuss some of these requirements, and present our progress towards a customizable simple-to-use modularization tool that leverages existing OWL-based tools and opens up their use for the CL and other ontologies

    Probabilistic Prediction of Wheel Squeal under Field Humidity Variation

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    This research examines the effect of changes in coefficient of friction due to humidity on the likelihood of wheel squeal events occurring in practice. Theoretical mechanics based modeling is developed and compared to a database of field measurements of wheel squeal occurrences at a field site in Australia. In particular, a relatively simplified model of wheel squeal is developed based on existing literature but notably incorporates probabilistic mechanics to account for field parameter variations and hence allows direct comparisons with field data. The model is then tuned to field site conditions at which over 2 million wheel passes have been monitored for a period of 3 years. The comparison indicates that field measured trends for the effect of relative humidity on coefficient of friction and hence the occurrences of wheel squeal have been able to be predicted using the very efficient model

    A method of predicting variable speed rail corrugation growth using standard statistical moments

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    Wear-type rail corrugation is a significant problem in the railway transport industry. Some recent work has suggested that speed control can be used as an effective tool to minimize the rate of corrugation growth. This has brought about the need to model corrugation growth under variable passing speed. Variable speed rail corrugation growth modelling normally consists of either numerical simulation of a sequence of varied speed wheel passes or direct integration of a probabilistic passing speed distribution function; both of which are computationally expensive. This paper investigates the use of the statistical moments of the speed probability density function to greatly improve the computational speed of variable speed corrugation growth models and compares results of changing standard deviation and skewness to numerical integration models. It also identifies the effects of individual statistical moments on corrugation growth to provide better insight into control methods. The new modelling method correlated well with the numerical integration models for small standard deviations in speed (less than 10%) and highlighted a need to consider kurtosis in predicting the performance of speed control based corrugation mitigation schemes. For larger standard deviations in speed, higher than 4th order effects need to be considered

    The Ionization Fraction in Dense Molecular Gas II: Massive Cores

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    We present an observational and theoretical study of the ionization fraction in several massive cores located in regions that are currently forming stellar clusters. Maps of the emission from the J = 1-> O transitions of C18O, DCO+, N2H+, and H13CO+, as well as the J = 2 -> 1 and J = 3 -> 2 transitions of CS, were obtained for each core. Core densities are determined via a large velocity gradient analysis with values typically 10^5 cm^-3. With the use of observations to constrain variables in the chemical calculations we derive electron fractions for our overall sample of 5 cores directly associated with star formation and 2 apparently starless cores. The electron abundances are found to lie within a small range, -6.9 < log10(x_e) < -7.3, and are consistent with previous work. We find no difference in the amount of ionization fraction between cores with and without associated star formation activity, nor is any difference found in electron abundances between the edge and center of the emission region. Thus our models are in agreement with the standard picture of cosmic rays as the primary source of ionization for molecular ions. With the addition of previously determined electron abundances for low mass cores, and even more massive cores associated with O and B clusters, we systematically examine the ionization fraction as a function of star formation activity. This analysis demonstrates that the most massive sources stand out as having the lowest electron abundances (x_e < 10^-8).Comment: 35 pages (8 figures), using aaspp4.sty, to be published in Astrophysical Journa

    The effects of passing speed distribution on rail corrugation growth rate

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    The transportation phenomenon known as wear-type rail corrugation is a significant problem in railway engineering, which manifests as a periodic wear pattern developing on the surface of the wheel and rail with use. Some field studies and recent theoretical results by the current authors have suggested that uniformity in pass speed causes an increase in corrugation growth rate. This paper presents the predicted change in corrugation growth rate and dominant wavelengths with change in passing speed distribution, based on state of the art cornering growth modelling techniques
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