7,214 research outputs found
Text Summarization Techniques: A Brief Survey
In recent years, there has been a explosion in the amount of text data from a
variety of sources. This volume of text is an invaluable source of information
and knowledge which needs to be effectively summarized to be useful. In this
review, the main approaches to automatic text summarization are described. We
review the different processes for summarization and describe the effectiveness
and shortcomings of the different methods.Comment: Some of references format have update
Generalized Causal Set d'Alembertians
We introduce a family of generalized d'Alembertian operators in D-dimensional
Minkowski spacetimes which are manifestly Lorentz-invariant, retarded, and
non-local, the extent of the nonlocality being governed by a single parameter
. The prototypes of these operators arose in earlier work as averages of
matrix operators meant to describe the propagation of a scalar field in a
causal set. We generalize the original definitions to produce an infinite
family of ''Generalized Causet Box (GCB) operators'' parametrized by certain
coefficients , and we derive the conditions on the latter needed for
the usual d'Alembertian to be recovered in the infrared limit. The continuum
average of a GCB operator is an integral operator, and it is these continuum
operators that we mainly study. To that end, we compute their action on plane
waves, or equivalently their Fourier transforms g(p) [p being the
momentum-vector]. For timelike p, g(p) has an imaginary part whose sign depends
on whether p is past or future-directed. For small p, g(p) is necessarily
proportional to p.p, but for large p it becomes constant, raising the
possibility of a genuinely Lorentzian perturbative regulator for quantum field
theory. We also address the question of whether or not the evolution defined by
the GCB operators is stable, finding evidence that the original 4D causal set
d'Alembertian is unstable, while its 2D counterpart is stable.Comment: 26 pages, 4 figure
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Transcriptomic Profiles of Monocyte-Derived Macrophages in Response to Escherichia coli is Associated with the Host Genetics.
Reactive Nitrogen Species (RNS) are a group of bactericidal molecules produced by macrophages in response to pathogens in a process called oxidative burst. Nitric oxide (NO-) is a member of RNS produced from arginine by inducible Nitric Oxide Synthase (iNOS) enzyme. The activity of iNOS and production of NO- by macrophages following stimulation is one of the indicators of macrophage polarization towards M1/proinflammatory. Production of NO- by bovine monocyte-derived macrophage (MDM) and mouse peritoneal macrophages has been shown to be strongly associated with host genetic with the heritability of 0.776 in bovine MDM and 0.8 in mouse peritoneal macrophages. However, the mechanism of genetic regulation of macrophage response has remained less explored. In the current study, the transcriptome of bovine MDMs was compared between two extreme phenotypes that had been classified as high and low responder based on NO- production. The results showed that 179 and 392 genes were differentially expressed (DE) between high and low responder groups at 3 and 18 hours after exposure to Escherichia coli, respectively. A set of 11 Transcription Factors (TFs) (STAT1, IRF7, SPI1, STAT4, IRF1, HIF1A, FOXO3, REL, NFAT5, HIC1, and IRF4) at 3 hours and a set of 13 TFs (STAT1, IRF1, HIF1A, STAT4, ATF4, TP63, EGR1, CDKN2A, RBL1, E2F1, PRDM1, GATA3, and IRF4) at 18 hours after exposure to E. coli were identified to be differentially regulated between the high and low responder phenotypes. These TFs were found to be divided into two clusters of inflammatory- and hypoxia-related TFs. Functional analysis revealed that some key canonical pathways such as phagocytosis, chemotaxis, antigen presentation, and cell-to-cell signalling are enriched among the over-expressed genes by high responder phenotype. Based on the results of this study, it was inferred that the functional characteristics of bovine MDMs are associated with NO-based classification. Since NO- production is strongly associated with host genetics, this study for the first time shows the distinct proinflammatory profiles of macrophages are controlled by the natural genetic polymorphism in an outbred population. In addition, the results suggest that genetics can be considered as a new dimension in the current model of macrophage polarization which is currently described by the combination of stimulants, only
Electrical and terahertz magnetospectroscopy studies of laser-patterned micro- and nanostructures on InAs-based heterostructures
Nanostructures fabricated from narrow-gap semiconductors with strong
spin-orbit interaction (SOI), such as InAs, can be used to filter momentum
modes of electrons and offer the possibility to create and detect
spin-polarized currents entirely by electric fields. Here, we present
magnetotransport and THz magnetospectroscopy investigations of Hall-bars with
back-gates made from in InGaAs/InAlAs quantum well structures with a strained 4
nm InAs inserted channel. The two-dimensional electron gas is at 53 nm depth
and has a carrier density of about cm and mobility of
about cm/Vs, after illumination. Electrical and THz optical
transport measurements at low temperatures and in high magnetic fields reveal
an effective mass of 0.038 and an anisotropic -factor of up to 20,
larger than for bulk InAs or InAs-based heterostructures. We demonstrate that
quasi-one-dimensional channels can be formed by micro-laser lithography. The
population of subbands is controlled by in-plane gates. Contrary to previous
reports symmetric and asymmetric in-plane gate voltages applied to quasi-one
dimensional channels did not show indications of SOI-induced anomalies in the
conductance.Comment: v1 did not contain references due to filename mix-up; v3 is revision
following referee report; v4 is corrected version following acceptance; v5 is
the published versio
Three-Dimensional Bioprinting Materials with Potential Application in Preprosthetic Surgery
Current methods in handling maxillofacial defects are not robust and are highly dependent on the surgeon’s skills and the inherent potential in the patients’ bodies for regenerating lost tissues. Employing custom-designed 3D printed scaffolds that securely and effectively reconstruct the defects by using tissue engineering and regenerative medicine techniques can revolutionize preprosthetic surgeries. Various polymers, ceramics, natural and synthetic bioplastics, proteins, biomolecules, living cells, and growth factors as well as their hybrid structures can be used in 3D printing of scaffolds, which are still under development by scientists. These scaffolds not only are beneficial due to their patient-specific design, but also may be able to prevent micromobility, make tension free soft tissue closure, and improve vascularity. In this manuscript, a review of materials employed in 3D bioprinting including bioceramics, biopolymers, composites, and metals is conducted. A discussion of the relevance of 3D bioprinting using these materials for craniofacial interventions is included as well as their potential to create analogs to craniofacial tissues, their benefits, limitations, and their application
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