977 research outputs found
Level Crossing Rate of Macrodiversity System in the Presence of Multipath Fading and Shadowing
Macrodiversity system including macrodiversity SC receiver and two microdiversity SC receivers is considered in this paper. Received signal experiences, simultaneously, both, long term fading and short term fading. Microdiversity SC receivers reduces Rayleigh fading effects on system performance and macrodiversity SC receiver mitigate Gamma shadowing effects on system performance. Closed form expressions for level crossing rate of microdiversity SC receivers output signals envelopes are calculated. This expression is used for evaluation of level crossing rate of macrodiversity SC receiver output signal envelope. Numerical expressions are illustrated to show the influence of Gamma shadowing severity on level crossing rate
Compressive Inverse Scattering II. SISO Measurements with Born scatterers
Inverse scattering methods capable of compressive imaging are proposed and
analyzed. The methods employ randomly and repeatedly (multiple-shot) the
single-input-single-output (SISO) measurements in which the probe frequencies,
the incident and the sampling directions are related in a precise way and are
capable of recovering exactly scatterers of sufficiently low sparsity.
For point targets, various sampling techniques are proposed to transform the
scattering matrix into the random Fourier matrix. The results for point targets
are then extended to the case of localized extended targets by interpolating
from grid points. In particular, an explicit error bound is derived for the
piece-wise constant interpolation which is shown to be a practical way of
discretizing localized extended targets and enabling the compressed sensing
techniques.
For distributed extended targets, the Littlewood-Paley basis is used in
analysis. A specially designed sampling scheme then transforms the scattering
matrix into a block-diagonal matrix with each block being the random Fourier
matrix corresponding to one of the multiple dyadic scales of the extended
target. In other words by the Littlewood-Paley basis and the proposed sampling
scheme the different dyadic scales of the target are decoupled and therefore
can be reconstructed scale-by-scale by the proposed method. Moreover, with
probes of any single frequency \om the coefficients in the Littlewood-Paley
expansion for scales up to \om/(2\pi) can be exactly recovered.Comment: Add a new section (Section 3) on localized extended target
Covariation Among Vowel Height Effects on Acoustic Measures
Covariation among vowel height effects on vowel intrinsic fundamental frequency (IF0), voice onset time (VOT), and voiceless interval duration (VID) is analyzed to assess the plausibility of a common physiological mechanism underlying variation in these measures. Phrases spoken by 20 young adults, containing words composed of initial voiceless stops or /s/ and high or low vowels, were produced in habitual and voluntarily increased F0 conditions. High vowels were associated with increased IF0 and longer VIDs. VOT and VID exhibited significant covariation with IF0 only for males at habitua
THE PEAK WINDOWING FOR PAPR REDUCTION IN SOFTWARE DEFINED RADIO BASE STATIONS
The utilization of the techniques for Peak to Average Power Ratio (PAPR) reduction makes the wireless infrastructure conform to rigorous telecommunication standard specifications (error vector magnitude (EVM), bit error rate (BER), transmit spectrum mask (TSM)). In modern modulation schemes reduction of PAPR is important requirement for distortion free and energy-efficient operation of power amplifiers (PA). In this paper novel implementation of Peak Windowing method for PAPR reduction in Software Defined Radio (SDR) Base Stations (BS) is presented. The measurement results in terms of EVM and ACPR are given for 5MHz, 10MHz, 15MHz, 20MHz Long-Term Evolution (LTE) and Wideband Code Division Multiple Access (WCDMA) modulations. In case of 10MHz LTE signal, we achieved PAPR=8dB, EVM=2.0%, ACPR -52dBc at modulated PA output, antenna point
Epidermolysa bullosa in Danish Hereford calves is caused by a deletion in LAMC2 gene
BACKGROUND
Heritable forms of epidermolysis bullosa (EB) constitute a heterogeneous group of skin disorders of genetic aetiology that are characterised by skin and mucous membrane blistering and ulceration in response to even minor trauma. Here we report the occurrence of EB in three Danish Hereford cattle from one herd.
RESULTS
Two of the animals were necropsied and showed oral mucosal blistering, skin ulcerations and partly loss of horn on the claws. Lesions were histologically characterized by subepidermal blisters and ulcers. Analysis of the family tree indicated that inbreeding and the transmission of a single recessive mutation from a common ancestor could be causative. We performed whole genome sequencing of one affected calf and searched all coding DNA variants. Thereby, we detected a homozygous 2.4 kb deletion encompassing the first exon of the LAMC2 gene, encoding for laminin gamma 2 protein. This loss of function mutation completely removes the start codon of this gene and is therefore predicted to be completely disruptive. The deletion co-segregates with the EB phenotype in the family and absent in normal cattle of various breeds. Verifying the homozygous private variants present in candidate genes allowed us to quickly identify the causative mutation and contribute to the final diagnosis of junctional EB in Hereford cattle.
CONCLUSIONS
Our investigation confirms the known role of laminin gamma 2 in EB aetiology and shows the importance of whole genome sequencing in the analysis of rare diseases in livestock
Inter-individual Variation in Cancer and Cardiometabolic Health Outcomes in Response to Coffee Consumption : a Critical Review
Funding Sources None declared. Conflict of Interest None declared. Author Contributions E.V. and B.d.R. designed the study. E.V. created the search strategy under the supervision of B.d.R.E.V. and B.d.R. conducted the literature search, evaluated articles, and interpreted the data. E.V. drafted the manuscriptand B.d.R and J.M.G. reviewed and revised the article.Peer reviewedPostprin
The EMBARC European Bronchiectasis Registry:protocol for an international observational study
Bronchiectasis is one of the most neglected diseases in respiratory medicine. There are no approved therapies and few large-scale, representative epidemiological studies. The EMBARC (European Multicentre Bronchiectasis Audit and Research Collaboration) registry is a prospective, pan-European observational study of patients with bronchiectasis. The inclusion criterion is a primary clinical diagnosis of bronchiectasis consisting of: 1) a clinical history consistent with bronchiectasis; and 2) computed tomography demonstrating bronchiectasis. Core exclusion criteria are: 1) bronchiectasis due to known cystic fibrosis; 2) age <18 years; and 3) patients who are unable or unwilling to provide informed consent. The study aims to enrol 1000 patients by April 2016 across at least 20 European countries, and 10 000 patients by March 2020. Patients will undergo a comprehensive baseline assessment and will be followed up annually for up to 5 years with the goal of providing high-quality longitudinal data on outcomes, treatment patterns and quality of life. Data from the registry will be available in the form of annual reports. and will be disseminated in conference presentations and peer-reviewed publications. The European Bronchiectasis Registry aims to make a major contribution to understanding the natural history of the disease, as well as guiding evidence-based decision making and facilitating large randomised controlled trials.info:eu-repo/semantics/publishedVersio
Relationships Between Bone Treatment Conditions and Co2+ Sorption Capacities
Co-60 is an important radionuclide in spent nuclear fuel and liquid radioactive wastes. For the purification of water containing Co2+, ions sorption on hydroxyapatite (Ca-10(PO4)(6)(OH)(2)) can be applied. The process is particularly cost-effective if biological apatite from animal bones is utilized. In this study, dependence between bovine bone treatment conditions and Co2+, sorption was investigated as a function of initial metal concentration. Eight sorbents were previously prepared using fractional factorial design, by simultaneous variations of five process variables between two levels: factor A-the type of the chemical reagent (H2O2 or NaOH), factor B-reagent concentration (0.1 mol/L or 2 mol/L), factor C-reaction temperature (20(o)C or 60(o)C), factor D-contact time (1h or 3h) and factor E-sample annealing (without or at 400(o)C). At this point, the effects of treatment factors on Co2+, sorption efficiency were evaluated using statistical analysis. Amounts of Co2+ sorbed, amounts of released Ca2+ ions and final pH values were considered as system responses. The results showed that the impact of various treatment factors was different for different starting concentrations of Co2+. Consequently, no statistically important relations could be established between treatment conditions and Co2+, sorption from 10(-4) and 5*10(-4) mol/L solutions, whereas thermal treatment at 400(o)C was the only statistically significant factor influencing sorption from the most concentrated solution (5*10(-3) mol/L). Depending on initial Co2+, concentration, various factors had statistically significant effect on equilibrium pH values, whereas no relation was found between bone treatment conditions and the amounts of Ca2+, released during the sorption.3rd International Conference on Radiation and Applications in Various Fields of Research (RAD), Jun 08-12, 2015, Budva, Montenegr
Native Brazilian Passion Fruit (Passiflora tenuifila) Modulates Gene Expression Related with Reverse Cholesterol Transport and Improves Insulin Resistance Biomarkers in Humans.
This study aimed to evaluate the impact of the consumption of Passiflora tenuifila, a native species of passion fruit, rich in bioactive compounds, mainly proanthocyanidins, and fibers on hyperlipidemic overweight individuals
BUILDING BRIDGES FOR INNOVATION IN AGEING : SYNERGIES BETWEEN ACTION GROUPS OF THE EIP ON AHA
The Strategic Implementation Plan of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) proposed six Action Groups. After almost three years of activity, many achievements have been obtained through commitments or collaborative work of the Action Groups. However, they have often worked in silos and, consequently, synergies between Action Groups have been proposed to strengthen the triple win of the EIP on AHA. The paper presents the methodology and current status of the Task Force on EIP on AHA synergies. Synergies are in line with the Action Groups' new Renovated Action Plan (2016-2018) to ensure that their future objectives are coherent and fully connected. The outcomes and impact of synergies are using the Monitoring and Assessment Framework for the EIP on AHA (MAFEIP). Eight proposals for synergies have been approved by the Task Force: Five cross-cutting synergies which can be used for all current and future synergies as they consider overarching domains (appropriate polypharmacy, citizen empowerment, teaching and coaching on AHA, deployment of synergies to EU regions, Responsible Research and Innovation), and three cross-cutting synergies focussing on current Action Group activities (falls, frailty, integrated care and chronic respiratory diseases).Peer reviewe
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