Penutupan Karang di Pulau Baranglompo dan Pulau Bone Batang Berdasarkan Metode Reef Check

The Research on “Coral Coverage in Baranglompo Island and Bone Batang Island Based on Reef Check Method” was conductedin April 2016. The aims of this study was to determine and to compare the condition of reefs in Baranglompo and Bone BatangIslands based on the percentage of life coral cover by using Reef Check methods. This study also aims to determine whichfactors that most affect the percentage of coral cover on each island i.e: abiotic factors (temperature, salinity and substrate inthe form of rock, rubble, sand, silt/clay); biotic factors (soft coral, recent killed coral, algae, sponges, fish and invertebratesassociate) and anthropogenic factors (garbage, ilegal fishing/bombs, stun, anchors, nets) were also investigated. Percentage oflife coral cover obtained by Line Intercept Transect (LIT) along 100 meters at a depth of 3 meters and 10 meters. The resultsshowed that the condition of coral reefs in Baranglompo was classified as moderate with an average percentage coral coverageof 42% at a depth of 3 meters and 27% at a depth of 10 meters. While the condition of coral reefs in Pulau Bone Batang wasrelatively good with average coral cover of 51% at 3 meters depth and moderate with average coral cover of 39% at 10 metersdepth. Condition of coral reefs in Bone Batang is better than Baranglompo islands. Anthropogenic impacts in the form of wasteis the most influential factor on coral cover on the island Baranglompo. Whereas fishing activities by using dinamite are thefactors that most influence on coral cover on the island of Bone Batang

Struktur Komunitas Echinodermata di Padang Lamun Pulau Tanakeke Kabupaten Takalar Sulawesi Selatan

Penelitian tentang struktur komunitas Echinodermata di padang lamun perairan desa Balangdatu, Pulau Tanakeke kabupaten Takalar Sulawesi Selatan telah dilakukan pada bulan Oktober 2016 - Pebruari 2017. Tujuan penelitian ini adalah untuk mengetahui struktur komunitas Echinodermata di padang lamun pulau Tanakeke. Pengambilan sampel dilakukan dengan metode transek kombinasi plot dengan ukuran plot 2 x 2 meter pada tiga stasiun berbeda. Analisis data mencakup penghitungan nilai kepadatan, Indeks keanekaragaman dan Indeks penyebaran. Hasil penelitian menunjukkan terdapat 11 spesies Echinodermata dari 7 suku. Kepadatan jenis tertinggi ditemukan pada Ophiocoma erinaceus yaitu 7,85 ind/m2. Indeks keanekaragaman tergolong rendah menunjukkan kondisi lingkungan yang tertekan. Nilai Indeks penyebaran yang di seluruh stasiun lebih dari satu, menunjukkan bahwa pola penyebaran individu cenderung mengelompok

Associations of depressive symptoms, social engagement and support, and lifestyle behaviors among non-Hispanic black and Hispanic men with chronic conditions in the United States

Self-management of depressive symptoms is influenced by co-morbidity, social support, and health-related behaviors. Men are less likely to discuss depressive moods and seek healthcare. This study examines factors associated with depressive symptoms among non-Hispanic Black and Hispanic men ages ≥40 years with ≥1 chronic condition in the U. S. Data from 1,907 non-Hispanic Black (n = 1,117) and Hispanic (n = 790) males with chronic conditions were analyzed using logistic regression to assess depressive symptoms, identified as a Patient Health Questionnaire-2 score ≥3. One model was fitted for all men, then separate models were fitted for non-Hispanic Black and Hispanic men, respectively. The models adjusted for sociodemographic, disease characteristics, health status, social engagement and support, and lifestyle behaviors. In the full model, Hispanic men (OR = 1.39, p = 0.017) and those taking more medications (OR = 1.10, p = 0.010) were more likely to have depressive symptoms. Social disconnection (OR = 1.65, p < 0.001), reliance on others for health management (OR = 1.04, p < 0.001), limited activity due to health (OR = 3.15, p < 0.001), self-care barriers (OR = 1.16, p < 0.001), healthcare frustration (OR = 1.13, p < 0.001), prolonged sitting (OR = 1.01, p = 0.030), and tobacco use (OR = 1.56, p = 0.002) increased likelihood of depressive symptoms. Common and unique factors associated with depressive symptoms were identified in models for non-Hispanic Black and Hispanic men, respectively. Findings highlight the dynamic interplay between depressive symptoms, social engagement, and lifestyle behaviors among non-Hispanic Black and Hispanic men with complex disease profiles. Efforts are needed to address depressive symptomatology through self-managing conditions, strengthening supportive networks, and alleviating burdens associated with healthcare interactions

Correction: CD93 is expressed on chronic myeloid leukemia stem cells and identifies a quiescent population which persists after tyrosine kinase inhibitor therapy

Correction to: Leukemia https://doi.org/10.1038/s41375-019-0684-

Feasibility and long-term results of focused radioguided parathyroidectomy using a "low" 37 MBq (1 mCi) (99m)Tc-sestamibi protocol

Aim of the present study was to investigate the feasibility and long-term results of focused radioguided parathyroidectomy using a "low" 37 MBq (1 mCi) (99m)Tc-sestamibi dose protocol compared to conventional "high 740 MBq (20 mCi) (99m)Tc-sestamibi dose protocol" in patients with primary hyperparathyroidism (PHPT). The data of focused radioguided surgery obtained in a group of 320 consecutive PHPT patients with high probability of the presence of a solitary parathyroid adenoma (PA) were studied. All patients underwent preoperative imaging work-up of double-tracer (99m)Tc-pertechnetate/(99m)Tc-sestamibi subtraction parathyroid scintigraphy (Sestamibi scintigraphy) and high resolution neck ultrasound (US). In 301/320 patients (96.6%) focused minimally invasive radioguided surgery was successfully performed by administering a "low" 37 MBq (1 mCi) (99m)Tc-sestamibi dose in the operating room 10 minutes before operation. No major intraoperative complications were recorded. Focused radioguided surgery required a mean time of 32 min and a mean hospital stay of 1.2 days. Local anesthesia was applied in 75 patients, 66 of whom (88%) were patients older than 65 years with comorbidities contraindicating general anesthesia. No case of persistent or recurrent PHPT was observed during post-surgical follow-up (range = 18–70 months; mean +/- SD = 15.3 +/- 9.1 months). Radiation exposure dose to the operating surgeon was 1.2 μSi/hour with the "low 37 MBq (1 mCi) (99m)Tc-sestamibi dose", and less than 1.0 μSi/hour for the other operating-room personnel. Focused low dose radioguided parathyroidectomy is a safe and effective means to localize parathyroid adenomas in patients affected by solitary PA thus reducing by 20 fold the radiation exposure dose to the patients and operating room personnel

Islet Formation during the Neonatal Development in Mice

The islet of Langerhans is a unique micro-organ within the exocrine pancreas, which is composed of insulin-secreting beta-cells, glucagon-secreting alpha-cells, somatostatin-secreting delta-cells, pancreatic polypeptide-secreting PP cells and ghrelin-secreting epsilon-cells. Islets also contain non-endocrine cell types such as endothelial cells. However, the mechanism(s) of islet formation is poorly understood due to technical difficulties in capturing this dynamic event in situ. We have developed a method to monitor beta-cell proliferation and islet formation in the intact pancreas using transgenic mice in which the beta-cells are specifically tagged with a fluorescent protein. Endocrine cells proliferate contiguously, forming branched cord-like structures in both embryos and neonates. Our study has revealed long stretches of interconnected islets located along large blood vessels in the neonatal pancreas. Alpha-cells span the elongated islet-like structures, which we hypothesize represent sites of fission and facilitate the eventual formation of discrete islets. We propose that islet formation occurs by a process of fission following contiguous endocrine cell proliferation, rather than by local aggregation or fusion of isolated beta-cells and islets. Mathematical modeling of the fission process in the neonatal islet formation is also presented

Limitations of Tc99m-MIBI-SPECT Imaging Scans in Persistent Primary Hyperparathyroidism

In primary hyperparathyroidism (PHPT) the predictive value of technetium 99m sestamibi single emission computed tomography (Tc99m-MIBI-SPECT) for localizing pathological parathyroid glands before a first parathyroidectomy (PTx) is 83-100%. Data are scarce in patients undergoing reoperative parathyroidectomy for persistent hyperparathyroidism. The aim of the present study was to determine the value of Tc99m-MIBI-SPECT in localizing residual hyperactive parathyroid tissue in patients with persistent primary hyperparathyroidism (PHPT) after initial excision of one or more pathological glands. We retrospectively evaluated the localizing accuracy of Tc99m-MIBI-SPECT scans in 19 consecutive patients with persistent PHPT who had a scan before reoperative parathyroidectomy. We used as controls 23 patients with sporadic PHPT who had a scan before initial surgery. In patients with persistent PHPT, Tc99m-MIBI-SPECT accurately localized a pathological parathyroid gland in 33% of cases before reoperative parathyroidectomy, compared to 61% before first PTx for sporadic PHPT. The Tc99m-MIBI-SPECT scan accurately localized intra-thyroidal glands in 2 of 7 cases and a mediastinal gland in 1 of 3 cases either before initial or reoperative parathyroidectomy. Our data suggest that the accuracy of Tc99m-MIBI-SPECT in localizing residual hyperactive glands is significantly lower before reoperative parathyroidectomy for persistent PHPT than before initial surgery for sporadic PHPT. These findings should be taken in consideration in the preoperative workup of patients with persistent primary hyperparathyroidis

Associations of depressive symptoms, social engagement and support, and lifestyle behaviors among non-Hispanic black and Hispanic men with chronic conditions in the United States

IntroductionSelf-management of depressive symptoms is influenced by co-morbidity, social support, and health-related behaviors. Men are less likely to discuss depressive moods and seek healthcare. This study examines factors associated with depressive symptoms among non-Hispanic Black and Hispanic men ages ≥40 years with ≥1 chronic condition in the U. S.MethodsData from 1,907 non-Hispanic Black (n = 1,117) and Hispanic (n = 790) males with chronic conditions were analyzed using logistic regression to assess depressive symptoms, identified as a Patient Health Questionnaire-2 score ≥3. One model was fitted for all men, then separate models were fitted for non-Hispanic Black and Hispanic men, respectively. The models adjusted for sociodemographic, disease characteristics, health status, social engagement and support, and lifestyle behaviors.ResultsIn the full model, Hispanic men (OR = 1.39, p = 0.017) and those taking more medications (OR = 1.10, p = 0.010) were more likely to have depressive symptoms. Social disconnection (OR = 1.65, p < 0.001), reliance on others for health management (OR = 1.04, p < 0.001), limited activity due to health (OR = 3.15, p < 0.001), self-care barriers (OR = 1.16, p < 0.001), healthcare frustration (OR = 1.13, p < 0.001), prolonged sitting (OR = 1.01, p = 0.030), and tobacco use (OR = 1.56, p = 0.002) increased likelihood of depressive symptoms. Common and unique factors associated with depressive symptoms were identified in models for non-Hispanic Black and Hispanic men, respectively.ConclusionFindings highlight the dynamic interplay between depressive symptoms, social engagement, and lifestyle behaviors among non-Hispanic Black and Hispanic men with complex disease profiles. Efforts are needed to address depressive symptomatology through self-managing conditions, strengthening supportive networks, and alleviating burdens associated with healthcare interactions