15,343 research outputs found
The Evolution of Overconfidence
Confidence is an essential ingredient of success in a wide range of domains
ranging from job performance and mental health, to sports, business, and
combat. Some authors have suggested that not just confidence but
overconfidence-believing you are better than you are in reality-is advantageous
because it serves to increase ambition, morale, resolve, persistence, or the
credibility of bluffing, generating a self-fulfilling prophecy in which
exaggerated confidence actually increases the probability of success. However,
overconfidence also leads to faulty assessments, unrealistic expectations, and
hazardous decisions, so it remains a puzzle how such a false belief could
evolve or remain stable in a population of competing strategies that include
accurate, unbiased beliefs. Here, we present an evolutionary model showing
that, counter-intuitively, overconfidence maximizes individual fitness and
populations will tend to become overconfident, as long as benefits from
contested resources are sufficiently large compared to the cost of competition.
In contrast, "rational" unbiased strategies are only stable under limited
conditions. The fact that overconfident populations are evolutionarily stable
in a wide range of environments may help to explain why overconfidence remains
prevalent today, even if it contributes to hubris, market bubbles, financial
collapses, policy failures, disasters, and costly wars.Comment: Supplementary Information include
Topological code Autotune
Many quantum systems are being investigated in the hope of building a
large-scale quantum computer. All of these systems suffer from decoherence,
resulting in errors during the execution of quantum gates. Quantum error
correction enables reliable quantum computation given unreliable hardware.
Unoptimized topological quantum error correction (TQEC), while still effective,
performs very suboptimally, especially at low error rates. Hand optimizing the
classical processing associated with a TQEC scheme for a specific system to
achieve better error tolerance can be extremely laborious. We describe a tool
Autotune capable of performing this optimization automatically, and give two
highly distinct examples of its use and extreme outperformance of unoptimized
TQEC. Autotune is designed to facilitate the precise study of real hardware
running TQEC with every quantum gate having a realistic, physics-based error
model.Comment: 13 pages, 17 figures, version accepted for publicatio
A CLIPS-based tool for aircraft pilot-vehicle interface design
The Pilot-Vehicle Interface of modern aircraft is the cognitive, sensory, and psychomotor link between the pilot, the avionics modules, and all other systems on board the aircraft. To assist pilot-vehicle interface designers, a C Language Integrated Production System (CLIPS) based tool was developed that allows design information to be stored in a table that can be modified by rules representing design knowledge. Developed for the Apple Macintosh, the tool allows users without any CLIPS programming experience to form simple rules using a point and click interface
On the Nature of Precursors in the Radio Pulsar Profiles
In the average profiles of several radio pulsars, the main pulse is
accompanied by the preceding component. This so called precursor is known for
its distinctive polarization, spectral, and fluctuation properties. Recent
single-pulse observations hint that the sporadic activity at the extreme
leading edge of the pulse may be prevalent in pulsars. We for the first time
propose a physical mechanism of this phenomenon. It is based on the induced
scattering of the main pulse radiation into the background. We show that the
scattered component is directed approximately along the ambient magnetic field
and, because of rotational aberration in the scattering region, appears in the
pulse profile as a precursor to the main pulse. Our model naturally explains
high linear polarization of the precursor emission, its spectral and
fluctuation peculiarities as well as suggests a specific connection between the
precursor and the main pulse at widely spaced frequencies. This is believed to
stimulate multifrequency single-pulse studies of intensity modulation in
different pulsars.Comment: 5 pages, no figures. Accepted for publication in MNRAS Letter
Contamination
Soil contamination occurs when substances are added to soil, resulting in increases in concentrations
above background or reference levels. Pollution may follow from contamination when contaminants
are present in amounts that are detrimental to soil quality and become harmful to the environment or
human health. Contamination can occur via a range of pathways including direct application to land and
indirect application from atmospheric deposition.
Contamination was identified by SEPA (2001) as a significant threat to soil quality in many parts of
Scotland. Towers et al. (2006) identified four principal contamination threats to Scottish soils: acidification;
eutrophication; metals; and pesticides. The Scottish Soil Framework (Scottish Government, 2009) set out
the potential impact of these threats on the principal soil functions.
Severe contamination can lead to “contaminated land” [as defined under Part IIA of the Environmental
Protection Act (1990)]. This report does not consider the state and impacts of contaminated land on
the wider environment in detail. For further information on contaminated land, see ‘Dealing with Land
Contamination in Scotland’ (SEPA, 2009).
This chapter considers the causes of soil contamination and their environmental and socio-economic
impacts before going on to discuss the status of, and trends in, levels of contaminants in Scotland’s soils
Gene identification for the cblD defect of vitamin B12 metabolism
Background Vitamin B12 (cobalamin) is an essential cofactor in several metabolic pathways. Intracellular conversion of cobalamin to its two coenzymes, adenosylcobalamin in mitochondria and methylcobalamin in the cytoplasm, is necessary for the homeostasis of methylmalonic acid and homocysteine. Nine defects of intracellular cobalamin metabolism have been defined by means of somatic complementation analysis. One of these defects, the cblD defect, can cause isolated methylmalonic aciduria, isolated homocystinuria, or both. Affected persons present with multisystem clinical abnormalities, including developmental, hematologic, neurologic, and metabolic findings. The gene responsible for the cblD defect has not been identified.
Methods We studied seven patients with the cblD defect, and skin fibroblasts from each were investigated in cell culture. Microcell-mediated chromosome transfer and refined genetic mapping were used to localize the responsible gene. This gene was transfected into cblD fibroblasts to test for the rescue of adenosylcobalamin and methylcobalamin synthesis.
Results The cblD gene was localized to human chromosome 2q23.2, and a candidate gene, designated MMADHC (methylmalonic aciduria, cblD type, and homocystinuria), was identified in this region. Transfection of wild-type MMADHC rescued the cellular phenotype, and the functional importance of mutant alleles was shown by means of transfection with mutant constructs. The predicted MMADHC protein has sequence homology with a bacterial ATP-binding cassette transporter and contains a putative cobalamin binding motif and a putative mitochondrial targeting sequence.
Conclusions Mutations in a gene we designated MMADHC are responsible for the cblD defect in vitamin B12 metabolism. Various mutations are associated with each of the three biochemical phenotypes of the disorder
Formation of Multipartite Entanglement Using Random Quantum Gates
The formation of multipartite quantum entanglement by repeated operation of
one and two qubit gates is examined. The resulting entanglement is evaluated
using two measures: the average bipartite entanglement and the Groverian
measure. A comparison is made between two geometries of the quantum register: a
one dimensional chain in which two-qubit gates apply only locally between
nearest neighbors and a non-local geometry in which such gates may apply
between any pair of qubits. More specifically, we use a combination of random
single qubit rotations and a fixed two-qubit gate such as the controlled-phase
gate. It is found that in the non-local geometry the entanglement is generated
at a higher rate. In both geometries, the Groverian measure converges to its
asymptotic value more slowly than the average bipartite entanglement. These
results are expected to have implications on different proposed geometries of
future quantum computers with local and non-local interactions between the
qubits.Comment: 7 pages, 5 figure
Systematically searching for and assessing the literature for self-management of chronic pain: A lay users' perspective
© 2014 Schofield et al.; licensee BioMed Central Ltd. Background: The Engaging with older adults in the development of strategies for the self management of chronic pain (EOPIC) study aims to design and develop self management strategies to enable older adults to manage their own pain. Involving older adults in research into chronic pain management will better enable the identification and development of strategies that are more appropriate for their use, but how can perspectives really be utilised to the best possible outcomes?. Method. Seven older adults were recruited through a local advertising campaign to take part. We also invited participants from the local pain services, individuals who had been involved in earlier phase of the EOPIC study and a previous ESRC funded project. The group undertook library training and research skills training to facilitate searching of the literature and identified sources of material. A grading tool was developed using perceived essential criteria identified by the older adults and material was graded according to the criteria within this scale. Results: Fifty-seven resources from over twenty-eight sources were identified. These materials were identified as being easily accessible, readable and relevant. Many of the web based materials were not always easy to find or readily available so they were excluded by the participants. All but one were UK based. Forty-four items were identified as meeting the key criteria for inclusion in the study. This included five key categories as follows; books, internet, magazines, leaflets, CD's/Tapes. Conclusion: This project was able to identify a number of exemplars of self management material along with some general rules regarding the categories identified. We must point out that the materials identified were not age specific, were often locally developed and would need to be adapted to older adults with chronic pain. For copyright issues we have not included them in this paper. The key message is really related to the format rather than the content. However, the group acknowledge that these may vary according to the requirements of each individual older adult and therefore recommend the development of a leaflet to help others in their search for resources. This leaflet has been developed as part of Phase IV of the EOPIC study
Contamination of spacecraft by recontact of dumped liquids
Liquids partially freeze when dumped from spacecraft producing particles which are released into free space at various velocities. Recontact of these particles with the spacecraft is possible for specific particle sizes and velocities and, therefore, can become contamination for experiments within the spacecraft or released experiments as a result of waste and potable water dumped from Space Shuttle. An examination of dump characteristics was conducted on STS-29 using both on-board video records and ground based measurements. A preliminary analysis of data from this flight indicates particle velocities are in the range of 30 to 75 ft/sec and recontact is possible for limited particle sizes
Global control and fast solid-state donor electron spin quantum computing
We propose a scheme for quantum information processing based on donor
electron spins in semiconductors, with an architecture complementary to the
original Kane proposal. We show that a naive implementation of electron spin
qubits provides only modest improvement over the Kane scheme, however through
the introduction of global gate control we are able to take full advantage of
the fast electron evolution timescales. We estimate that the latent clock speed
is 100-1000 times that of the nuclear spin quantum computer with the ratio
approaching the level.Comment: 9 pages, 9 figure
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