Synthetic and antibacterial studies of rhodanine derivatives with indol-2,3-diones

1275-1278A facile synthesis of new isatylidene and quinoline derivatives is described by treatment of rhodanine with indol-2,3-diones via Knoevenagel condensation and Pfitzinger reaction respectively. The reaction of indol-2,3-dione derivatives with five membered heterocycles, viz rhodanine under normal and basic conditions is described. While refluxing with ethanol it afford 3,4-dihydro-3-[2-thioxo-4 –thiazolidinone]indol-2-one 3, under basic conditions l-methyl-2-thio-4-thiazolidino[5,4-b] quinoline-4-carboxylic acid 4 is obtained. The compounds 3 and 4 have been characterized by spectral studies and elemental analyses and screened for antibacterial activity

Health care and work with older adults and their caregivers

The population of older adults in the United States has grown exponentially over the past few decades. This chapter looks at the unique challenges of meeting the comprehensive healthcare needs of this population. It examines the implications for social policy and gerontological practice and highlights the current models of entitlements and support services for older adults. The chapter also illustrates knowledge and skills required by social workers in this field, and discusses the recommendations for holistic competence. It focuses on four federal social policies that have guided the development of healthcare in the United States. These policies have had a substantial impact on who is eligible for services, the type of services one is entitled to, the quality of services provided, and ultimately the lives of individuals affected by them. The four major social policies are Medicare, Medicaid, the Older Americans Act (OAA), and the Supplemental Nutritional Assistance Program (SNAP)